Q297H4 (Q297H4_DROPS) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
GA18262 EMBL EAL28231.1
EC=2.1.1.43 EMBL EAL28231.1

Gene names

Name:	Dpse\GA18262 EMBL EAL28231.1
ORF Names:	Dpse_GA18262 EMBL EAL28231.1, GA18262 FlyBase FBgn0078268

Organism

Drosophila pseudoobscura pseudoobscura (Fruit fly) [Reference proteome] EMBL EAL28231.1

Taxonomic identifier

46245 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Panarthropoda › Arthropoda › Mandibulata › Pancrustacea › Hexapoda › Insecta › Dicondylia › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Eremoneura › Cyclorrhapha › Schizophora › Acalyptratae › Ephydroidea › Drosophilidae › Drosophilinae › Drosophilini › Drosophilina › Drosophiliti › Drosophila › Sophophora › obscura group › pseudoobscura subgroup › Drosophila pseudoobscura

Protein attributes

Sequence length	232 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone]. SAAS SAAS007728 S-adenosyl-L-methionine + histone L-lysine = S-adenosyl-L-homocysteine + histone N(6)-methyl-L-lysine. RuleBase RU004542
Subcellular location	Nucleus By similarity RuleBase RU004542.
Sequence similarities	Contains 1 SET domain. RuleBase RU004538 SAAS SAAS001214 Contains 1 pre-SET domain. RuleBase RU004542 SAAS SAAS001214

Ontologies

Keywords
Cellular component	Chromosome SAAS SAAS007728 Nucleus RuleBase RU004542 SAAS SAAS007728
Molecular function	Methyltransferase SAAS SAAS007728 RuleBase RU004542 EMBL EAL28231.1 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	chromosome Inferred from electronic annotation. Source: UniProtKB-KW nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	histone-lysine N-methyltransferase activity Inferred from electronic annotation. Source: EC zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q297H4 [UniParc]. Last modified April 4, 2006. Version 1. Checksum: 3AF1A8CDF518295D	FASTA	232	26,479
	10 20 30 40 50 60 MAQSRMVVND DYEHPDHLEY ILESVLMPSD ESLDFNLLRN DYNSVLLHKC QCDKGGCANN 70 80 90 100 110 120 ERCSHGGAYE YCPDGKELIQ RQTNKTGNIP IVECNSFCEC RIEFCTNRLV QYGPRANLEV 130 140 150 160 170 180 FNSPTYKSKG VRTKVSIPCG AFICEYAGEI LTISEAKRRI VTNKKLGSMN YVLILNEYTK 190 200 210 220 230 TDDCYEVKRQ VTIIDPSRRG NIGRYINHSC DPNCQITAVR IDCPIPKICE FY

References

[1]

"Comparative genome sequencing of Drosophila pseudoobscura: chromosomal, gene, and cis-element evolution." Richards S., Liu Y., Bettencourt B.R., Hradecky P., Letovsky S., Nielsen R., Thornton K., Hubisz M.J., Chen R., Meisel R.P., Couronne O., Hua S., Smith M.A., Zhang P., Liu J., Bussemaker H.J., van Batenburg M.F., Howells S.L. , Scherer S.E., Sodergren E., Matthews B.B., Crosby M.A., Schroeder A.J., Ortiz-Barrientos D., Rives C.M., Metzker M.L., Muzny D.M., Scott G., Steffen D., Wheeler D.A., Worley K.C., Havlak P., Durbin K.J., Egan A., Gill R., Hume J., Morgan M.B., Miner G., Hamilton C., Huang Y., Waldron L., Verduzco D., Clerc-Blankenburg K.P., Dubchak I., Noor M.A.F., Anderson W., White K.P., Clark A.G., Schaeffer S.W., Gelbart W.M., Weinstock G.M., Gibbs R.A. Genome Res. 15:1-18(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MV2-25 / Tucson 14011-0121.94.

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Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CM000070 Genomic DNA. Translation: EAL28231.1.
RefSeq	XP_001359088.1. XM_001359051.2.
3D structure databases
ProteinModelPortal	Q297H4.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	FBtr0283340; FBpp0281778; FBgn0078268.
GeneID	4802104.
KEGG	dpo:Dpse_GA18262.
Organism-specific databases
FlyBase	FBgn0078268. Dpse\GA18262.
Phylogenomic databases
InParanoid	Q297H4.
KO	K11433.
OMA	SRRGNIG.
OrthoDB	EOG4VDNFF.
Family and domain databases
InterPro	IPR007728. Pre-SET_dom. IPR001214. SET_dom. [Graphical view]
Pfam	PF05033. Pre-SET. 1 hit. PF00856. SET. 1 hit. [Graphical view]
SMART	SM00317. SET. 1 hit. [Graphical view]
PROSITE	PS50867. PRE_SET. 1 hit. PS50280. SET. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q297H4_DROPS

Accession

Primary (citable) accession number: Q297H4

Entry history

Integrated into UniProtKB/TrEMBL:	April 4, 2006
Last sequence update:	April 4, 2006
Last modified:	May 29, 2013
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)