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Q297H4

- Q297H4_DROPS

UniProt

Q297H4 - Q297H4_DROPS

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Protein
Submitted name: GA18262
Gene
Dpse\GA18262, Dpse_GA18262, GA18262
Organism
Drosophila pseudoobscura pseudoobscura (Fruit fly)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].UniRule annotation
S-adenosyl-L-methionine + histone L-lysine = S-adenosyl-L-homocysteine + histone N(6)-methyl-L-lysine.

GO - Molecular functioni

  1. histone-lysine N-methyltransferase activity Source: UniProtKB-EC
  2. zinc ion binding Source: InterPro
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Keywords - Molecular functioni

    MethyltransferaseUniRule annotationImported, Transferase

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    GA18262Imported (EC:2.1.1.43Imported)
    Gene namesi
    Name:Dpse\GA18262Imported
    ORF Names:Dpse_GA18262Imported, GA18262Imported
    OrganismiDrosophila pseudoobscura pseudoobscura (Fruit fly)Imported
    Taxonomic identifieri46245 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
    ProteomesiUP000001819: Chromosome 2

    Organism-specific databases

    FlyBaseiFBgn0078268. Dpse\GA18262.

    Subcellular locationi

    Nucleus By similarity UniRule annotation

    GO - Cellular componenti

    1. chromosome Source: UniProtKB-KW
    2. nucleus Source: UniProtKB-SubCell
    Complete GO annotation...

    Keywords - Cellular componenti

    ChromosomeSAAS annotations, NucleusUniRule annotationSAAS annotations

    Interactioni

    Protein-protein interaction databases

    STRINGi7237.FBpp0281778.

    Structurei

    3D structure databases

    ProteinModelPortaliQ297H4.

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 SET domain.UniRule annotation
    Contains 1 pre-SET domain.UniRule annotation
    Contains SET domain.SAAS annotations
    Contains pre-SET domain.SAAS annotations

    Phylogenomic databases

    InParanoidiQ297H4.
    KOiK11433.
    OMAiRGNIGRY.
    OrthoDBiEOG744T8D.
    PhylomeDBiQ297H4.

    Family and domain databases

    InterProiIPR007728. Pre-SET_dom.
    IPR001214. SET_dom.
    [Graphical view]
    PfamiPF05033. Pre-SET. 1 hit.
    PF00856. SET. 1 hit.
    [Graphical view]
    SMARTiSM00317. SET. 1 hit.
    [Graphical view]
    PROSITEiPS50867. PRE_SET. 1 hit.
    PS50280. SET. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q297H4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAQSRMVVND DYEHPDHLEY ILESVLMPSD ESLDFNLLRN DYNSVLLHKC    50
    QCDKGGCANN ERCSHGGAYE YCPDGKELIQ RQTNKTGNIP IVECNSFCEC 100
    RIEFCTNRLV QYGPRANLEV FNSPTYKSKG VRTKVSIPCG AFICEYAGEI 150
    LTISEAKRRI VTNKKLGSMN YVLILNEYTK TDDCYEVKRQ VTIIDPSRRG 200
    NIGRYINHSC DPNCQITAVR IDCPIPKICE FY 232
    Length:232
    Mass (Da):26,479
    Last modified:April 4, 2006 - v1
    Checksum:i3AF1A8CDF518295D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CM000070 Genomic DNA. Translation: EAL28231.1.
    RefSeqiXP_001359088.1. XM_001359051.2.

    Genome annotation databases

    EnsemblMetazoaiFBtr0283340; FBpp0281778; FBgn0078268.
    GeneIDi4802104.
    KEGGidpo:Dpse_GA18262.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CM000070 Genomic DNA. Translation: EAL28231.1 .
    RefSeqi XP_001359088.1. XM_001359051.2.

    3D structure databases

    ProteinModelPortali Q297H4.
    ModBasei Search...

    Protein-protein interaction databases

    STRINGi 7237.FBpp0281778.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai FBtr0283340 ; FBpp0281778 ; FBgn0078268 .
    GeneIDi 4802104.
    KEGGi dpo:Dpse_GA18262.

    Organism-specific databases

    FlyBasei FBgn0078268. Dpse\GA18262.

    Phylogenomic databases

    InParanoidi Q297H4.
    KOi K11433.
    OMAi RGNIGRY.
    OrthoDBi EOG744T8D.
    PhylomeDBi Q297H4.

    Family and domain databases

    InterProi IPR007728. Pre-SET_dom.
    IPR001214. SET_dom.
    [Graphical view ]
    Pfami PF05033. Pre-SET. 1 hit.
    PF00856. SET. 1 hit.
    [Graphical view ]
    SMARTi SM00317. SET. 1 hit.
    [Graphical view ]
    PROSITEi PS50867. PRE_SET. 1 hit.
    PS50280. SET. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Comparative genome sequencing of Drosophila pseudoobscura: chromosomal, gene, and cis-element evolution."
      Richards S., Liu Y., Bettencourt B.R., Hradecky P., Letovsky S., Nielsen R., Thornton K., Hubisz M.J., Chen R., Meisel R.P., Couronne O., Hua S., Smith M.A., Zhang P., Liu J., Bussemaker H.J., van Batenburg M.F., Howells S.L.
      , Scherer S.E., Sodergren E., Matthews B.B., Crosby M.A., Schroeder A.J., Ortiz-Barrientos D., Rives C.M., Metzker M.L., Muzny D.M., Scott G., Steffen D., Wheeler D.A., Worley K.C., Havlak P., Durbin K.J., Egan A., Gill R., Hume J., Morgan M.B., Miner G., Hamilton C., Huang Y., Waldron L., Verduzco D., Clerc-Blankenburg K.P., Dubchak I., Noor M.A.F., Anderson W., White K.P., Clark A.G., Schaeffer S.W., Gelbart W.M., Weinstock G.M., Gibbs R.A.
      Genome Res. 15:1-18(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: MV2-25 / Tucson 14011-0121.94.
    2. "Evolution of genes and genomes on the Drosophila phylogeny."
      Drosophila 12 genomes consortium
      Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: MV2-25Imported.

    Entry informationi

    Entry nameiQ297H4_DROPS
    AccessioniPrimary (citable) accession number: Q297H4
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 4, 2006
    Last sequence update: April 4, 2006
    Last modified: September 3, 2014
    This is version 56 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    External Data

    Dasty 3

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