Q297B6 (Q297B6_DROPS) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
GA17282 EMBL EAL28290.2
EC=2.7.1.- EMBL EAL28290.2

Gene names

Name:	GA17282 FlyBase FBgn0077295
Synonyms:	Dpse\GA17282 EMBL EAL28290.2
ORF Names:	Dpse_GA17282 EMBL EAL28290.2

Organism

Drosophila pseudoobscura pseudoobscura (Fruit fly) [Reference proteome] EMBL EAL28290.2

Taxonomic identifier

46245 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Panarthropoda › Arthropoda › Mandibulata › Pancrustacea › Hexapoda › Insecta › Dicondylia › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Eremoneura › Cyclorrhapha › Schizophora › Acalyptratae › Ephydroidea › Drosophilidae › Drosophilinae › Drosophilini › Drosophilina › Drosophiliti › Drosophila › Sophophora › obscura group › pseudoobscura subgroup › Drosophila pseudoobscura

Protein attributes

Sequence length	466 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the hexokinase family. RuleBase RU004510

Ontologies

Keywords
Biological process	Glycolysis SAAS SAAS022672
Ligand	ATP-binding SAAS SAAS022672 Nucleotide-binding
Molecular function	Kinase SAAS SAAS022672 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	glycolysis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW kinase activity Inferred from electronic annotation. Source: UniProtKB-KW phosphotransferase activity, alcohol group as acceptor Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q297B6 [UniParc]. Last modified October 14, 2008. Version 2. Checksum: 240574A1D7B972FD	FASTA	466	52,304
	10 20 30 40 50 60 MAGPIFKPEV DFPEVYKLCQ MFVPSENDLV KVRDTMNREM TAGLSKEGHD RSSVPCYLSY 70 80 90 100 110 120 VQDLPSGRER GRFLALEMMP TNCRIMLVRF SSEKDVYMSS KCVIIPHSIA AAKGTELFNF 130 140 150 160 170 180 LASNIATFVK DKKVEKENLP MGIAFAFSLN KLALDVGILI AWTKEFGATG AIGKDVVQLL 190 200 210 220 230 240 RDALAKFPEI MVNILGIINV AIGSLLALCW TQPDTRIGLN MGNITNSCYV EEVDNCHMYT 250 260 270 280 290 300 GTNNKSIMIV NTDWAHFGDG GQLDFIRNEF DKTLDESSTN PGHRIYEKFS GALFISELVR 310 320 330 340 350 360 MVIVRLMRNG TIFEGQTLDL ISNQWRMDMS SVFDLDSDPP GVYTKAQEVM EKYRIRHCKE 370 380 390 400 410 420 RDLAAVRYIS NIILSRAAMM LSSGVACLIN RMKIAQISIS VDGGIYRLNQ TFQTVINKYT 430 440 450 460 LQLTDPRYKF EYVVNQDSCG VGAAIMAGLA HADKYRGESK IFELDF

References

[1]

"Comparative genome sequencing of Drosophila pseudoobscura: chromosomal, gene, and cis-element evolution." Richards S., Liu Y., Bettencourt B.R., Hradecky P., Letovsky S., Nielsen R., Thornton K., Hubisz M.J., Chen R., Meisel R.P., Couronne O., Hua S., Smith M.A., Zhang P., Liu J., Bussemaker H.J., van Batenburg M.F., Howells S.L. , Scherer S.E., Sodergren E., Matthews B.B., Crosby M.A., Schroeder A.J., Ortiz-Barrientos D., Rives C.M., Metzker M.L., Muzny D.M., Scott G., Steffen D., Wheeler D.A., Worley K.C., Havlak P., Durbin K.J., Egan A., Gill R., Hume J., Morgan M.B., Miner G., Hamilton C., Huang Y., Waldron L., Verduzco D., Clerc-Blankenburg K.P., Dubchak I., Noor M.A.F., Anderson W., White K.P., Clark A.G., Schaeffer S.W., Gelbart W.M., Weinstock G.M., Gibbs R.A. Genome Res. 15:1-18(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MV2-25 / Tucson 14011-0121.94.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CM000070 Genomic DNA. Translation: EAL28290.2.
RefSeq	XP_001359146.2. XM_001359109.2.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	7237.FBpp0284251.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	FBtr0285813; FBpp0284251; FBgn0077295.
GeneID	4802174.
KEGG	dpo:Dpse_GA17282.
Organism-specific databases
FlyBase	FBgn0077295. Dpse\GA17282.
Phylogenomic databases
InParanoid	Q297B6.
KO	K00844.
OrthoDB	EOG4TDZ1G.
Family and domain databases
InterPro	IPR001312. Hexokinase. IPR022673. Hexokinase_C. IPR022672. Hexokinase_N. [Graphical view]
PANTHER	PTHR19443. PTHR19443. 1 hit.
Pfam	PF00349. Hexokinase_1. 1 hit. PF03727. Hexokinase_2. 1 hit. [Graphical view]
PRINTS	PR00475. HEXOKINASE.
ProtoNet	Search...

Entry information

Entry name

Q297B6_DROPS

Accession

Primary (citable) accession number: Q297B6

Entry history

Integrated into UniProtKB/TrEMBL:	April 4, 2006
Last sequence update:	October 14, 2008
Last modified:	May 1, 2013
This is version 40 of the entry and version 2 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)