Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Interferon beta

Gene

interferon-beta-1

Organism
Sus scrofa (Pig)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionCytokineUniRule annotationSAAS annotation
Biological processAntiviral defenseUniRule annotationSAAS annotation

Enzyme and pathway databases

ReactomeiR-SSC-909733. Interferon alpha/beta signaling.
R-SSC-912694. Regulation of IFNA signaling.
R-SSC-918233. TRAF3-dependent IRF activation pathway.
R-SSC-933541. TRAF6 mediated IRF7 activation.
R-SSC-983231. Factors involved in megakaryocyte development and platelet production.

Names & Taxonomyi

Protein namesi
Submitted name:
Interferon betaImported
Submitted name:
Interferon, beta 1, fibroblastImported
Submitted name:
Interferon-beta-1Imported
Gene namesi
Name:interferon-beta-1Imported
Synonyms:IFN-betaImported, IFNBImported, IFNB1Imported, interferon-beta/ poIFN-betaImported
OrganismiSus scrofa (Pig)
Taxonomic identifieri9823 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaSuinaSuidaeSus
Proteomesi
  • UP000008227 Componenti: Chromosome 1

Subcellular locationi

  • Secreted SAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

SecretedSAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_501084287322 – 186Sequence analysisAdd BLAST165

Keywords - PTMi

Disulfide bondSAAS annotation

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9823.ENSSSCP00000005550.

Family & Domainsi

Sequence similaritiesi

Belongs to the alpha/beta interferon family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410J0RY. Eukaryota.
ENOG41113EJ. LUCA.
GeneTreeiENSGT00760000119150.
HOVERGENiHBG052086.
OMAiSSTGWNE.
OrthoDBiEOG091G0V76.
TreeFamiTF336177.

Family and domain databases

CDDicd00095. IFab. 1 hit.
InterProiView protein in InterPro
IPR009079. 4_helix_cytokine-like_core.
IPR000471. Interferon_alpha/beta/delta.
IPR015588. Interferon_beta.
PANTHERiPTHR11691. PTHR11691. 1 hit.
PTHR11691:SF56. PTHR11691:SF56. 1 hit.
PfamiView protein in Pfam
PF00143. Interferon. 1 hit.
PRINTSiPR00266. INTERFERONAB.
SMARTiView protein in SMART
SM00076. IFabd. 1 hit.
SUPFAMiSSF47266. SSF47266. 1 hit.
PROSITEiView protein in PROSITE
PS00252. INTERFERON_A_B_D. 1 hit.

Sequencei

Sequence statusi: Complete.

Q29412-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MANKCILQIA LLMCFSTTAL SMSYDVLRYQ QRSSNLACQK LLGQLPGTPQ
60 70 80 90 100
YCLEDRMNFE VPEEIMQPPQ FQKEDAVLII HEMLQQIFGI LRRNFSSTGW
110 120 130 140 150
NETVIKTILV ELDGQMDDLE TILEEIMEEE NFPRGDMTIL HLKKYYLSIL
160 170 180
QYLKSKEYRS CAWTVVQVEI LRNFSFLNRL TDYLRN
Length:186
Mass (Da):21,878
Last modified:November 1, 1996 - v1
Checksum:i5F16B8B3C3AE603D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FP102266 Genomic DNA. No translation available.
M86762 Genomic DNA. Translation: AAA31056.1.
S41178 Genomic DNA. Translation: AAB22723.1.
GQ415073 mRNA. Translation: ACV42408.1.
JN391525 Genomic DNA. Translation: AEO19707.1.
UniGeneiSsc.42778.

Genome annotation databases

EnsembliENSSSCT00000005691; ENSSSCP00000005550; ENSSSCG00000005163.

Similar proteinsi

Entry informationi

Entry nameiQ29412_PIG
AccessioniPrimary (citable) accession number: Q29412
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: August 30, 2017
This is version 115 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported