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Protein
Submitted name:

Interferon beta

Gene

interferon-beta-1

Organism
Sus scrofa (Pig)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionCytokineUniRule annotationSAAS annotation
Biological processAntiviral defenseUniRule annotationSAAS annotation

Enzyme and pathway databases

ReactomeiR-SSC-909733 Interferon alpha/beta signaling
R-SSC-912694 Regulation of IFNA signaling
R-SSC-918233 TRAF3-dependent IRF activation pathway
R-SSC-933541 TRAF6 mediated IRF7 activation
R-SSC-983231 Factors involved in megakaryocyte development and platelet production

Names & Taxonomyi

Protein namesi
Submitted name:
Interferon betaImported
Submitted name:
Interferon-beta-1Imported
Gene namesi
Name:interferon-beta-1Imported
Synonyms:IFN-betaImported, IFNBImported, IFNB1Imported, interferon-beta/ poIFN-betaImported
OrganismiSus scrofa (Pig)Imported
Taxonomic identifieri9823 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaSuinaSuidaeSus
Proteomesi
  • UP000008227 Componenti: Chromosome 1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

SecretedSAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_501458609422 – 186Sequence analysisAdd BLAST165

Keywords - PTMi

Disulfide bondSAAS annotation

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9823.ENSSSCP00000005550

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili109 – 129Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the alpha/beta interferon family.UniRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis, SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410J0RY Eukaryota
ENOG41113EJ LUCA
GeneTreeiENSGT00760000119150
HOVERGENiHBG052086
OMAiCLKDRMN
OrthoDBiEOG091G0V76
TreeFamiTF336177

Family and domain databases

CDDicd00095 IFab, 1 hit
InterProiView protein in InterPro
IPR009079 4_helix_cytokine-like_core
IPR000471 Interferon_alpha/beta/delta
IPR015588 Interferon_beta
PANTHERiPTHR11691 PTHR11691, 1 hit
PTHR11691:SF43 PTHR11691:SF43, 1 hit
PfamiView protein in Pfam
PF00143 Interferon, 1 hit
PRINTSiPR00266 INTERFERONAB
SMARTiView protein in SMART
SM00076 IFabd, 1 hit
SUPFAMiSSF47266 SSF47266, 1 hit
PROSITEiView protein in PROSITE
PS00252 INTERFERON_A_B_D, 1 hit

Sequencei

Sequence statusi: Complete.

Q29412-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MANKCILQIA LLMCFSTTAL SMSYDVLRYQ QRSSNLACQK LLGQLPGTPQ
60 70 80 90 100
YCLEDRMNFE VPEEIMQPPQ FQKEDAVLII HEMLQQIFGI LRRNFSSTGW
110 120 130 140 150
NETVIKTILV ELDGQMDDLE TILEEIMEEE NFPRGDMTIL HLKKYYLSIL
160 170 180
QYLKSKEYRS CAWTVVQVEI LRNFSFLNRL TDYLRN
Length:186
Mass (Da):21,878
Last modified:November 1, 1996 - v1
Checksum:i5F16B8B3C3AE603D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AEMK02000004 Genomic DNA No translation available.
M86762 Genomic DNA Translation: AAA31056.1
S41178 Genomic DNA Translation: AAB22723.1
GQ415073 mRNA Translation: ACV42408.1
JN391525 Genomic DNA Translation: AEO19707.1
UniGeneiSsc.42778

Genome annotation databases

EnsembliENSSSCT00000005691; ENSSSCP00000005550; ENSSSCG00000005163

Similar proteinsi

Entry informationi

Entry nameiQ29412_PIG
AccessioniPrimary (citable) accession number: Q29412
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: May 23, 2018
This is version 124 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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