Q29097 (Q29097_PIG) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: P-selectin EMBL AAA79007.1
Organism	Sus scrofa (Pig) EMBL AAA79007.1
Taxonomic identifier	9823 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Laurasiatheria › Cetartiodactyla › Suina › Suidae › Sus

Protein attributes

Sequence length	646 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 C-type lectin domain. SAAS SAAS001304

Ontologies

Keywords
Domain	EGF-like domain SAAS SAAS000436 Repeat SAAS SAAS001304 Signal EMBL AAA79007.1 Sushi SAAS SAAS000436
Ligand	Lectin SAAS SAAS001304 EMBL AAA79007.1
PTM	Disulfide bond SAAS SAAS000436
Gene Ontology (GO)
Biological_process	cell adhesion Inferred from electronic annotation. Source: InterPro
Cellular_component	membrane Inferred from electronic annotation. Source: InterPro
Molecular_function	carbohydrate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 41	41	Potential EMBL AAA79007.1
	Chain	42 – 646	605	P-selectin EMBL AAA79007.1		PRO_5000142712

Sequences

	Sequence		Length	Mass (Da)
	Q29097 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 3863F4AFE09F0BB6	FASTA	646	71,128
	10 20 30 40 50 60 MASCLKAICN WRFQRVSFRT VQLLFFNALI SDLMNQKGVA AWTYNYSTSA YSWNTSRVFC 70 80 90 100 110 120 QRYFTDLVAI QNKKEIAYLN DVIPYYSSYY WIGMRKINNK WTWVGTKKTL TQEAENWAKN 130 140 150 160 170 180 EPNNESNNQD CVEMYIKSPL APGKWNDEPC VKRKRALCYT ASCQSTSCSK QGECTETIGN 190 200 210 220 230 240 YTCSCYSGFY GPRCEYVKEC GEFKLPQYVL TNCSHPLGNF SFNSQCSFHC AEGYTLNGPS 250 260 270 280 290 300 ELECLASGNW THPPPQCVAV QCPALKSPEK GNMACLHSEK AFQYQSSCNF SCEEGYALVG 310 320 330 340 350 360 PEVVQCQASG MWTAPVPVCK AITCEPLESP VRGSMDCFPS SRAFQYNTSC SFRCAKGFTL 370 380 390 400 410 420 RGADTVRCSN LGQWTAPAPV CQALQCQDLP APEKAQVNCS HPFGAFRYQS TCSFTCDEGS 430 440 450 460 470 480 SLVGASVLQC LETGNWSAPA PECQGISIVS APPPEVRCPA LITPEQGTMH CQHHLGTFGL 490 500 510 520 530 540 NTTCYFRCKT GFTIMGNNAL RCRSSGQWTA VAPVCRAVKC YELHITGPIV MNCSNPWGSF 550 560 570 580 590 600 SYGSTCSFHC PEGQLLNGSE LTVCKENGEW STTMPTCLAG PLTIQEALTY FGGAVASTTG 610 620 630 640 LVMGGTLLAL LRKRRRQKDD GKSPLSPQSH LGTYGVFTNA AFDPNP

References

[1]	"Adhesion of human neutrophils to complement-stimulated porcine endothelial cells is mediated by surface bound C3b and porcine P-selectin." Rollins S.A., Johnson K.K., Birks C.W., Matis L.A., Rother R.P. Submitted (OCT-1995) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Aorta EMBL AAA79007.1.
[2]	"TNF-alpha, IL-4, and IFN-gamma regulate differential expression of P- and E-selectin expression by porcine aortic endothelial cells." Stocker C.J., Sugars K.L., Harari O.A., Landis R.C., Morley B.J., Haskard D.O. J. Immunol. 164:3309-3315(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Tissue: Aorta EMBL AAF43272.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L39075 Genomic DNA. Translation: AAA79007.1. AF163766 mRNA. Translation: AAF43272.1.
RefSeq	NP_999243.1. NM_214078.1.
UniGene	Ssc.290.
3D structure databases
HSSP	HSSP built from PDB template 1FSB based on UniProtKB P16109.
ProteinModelPortal	Q29097.
SMR	Q29097. Positions 42-199.
ModBase	Search...
Protein-protein interaction databases
STRING	9823.ENSSSCP00000006702.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	397150.
KEGG	ssc:397150.
Organism-specific databases
CTD	6403.
Phylogenomic databases
eggNOG	NOG242963.
HOGENOM	HOG000236254.
HOVERGEN	HBG052375.
KO	K06496.
Family and domain databases
Gene3D	3.10.100.10. 1 hit.
InterPro	IPR001304. C-type_lectin. IPR016186. C-type_lectin-like. IPR018378. C-type_lectin_CS. IPR016187. C-type_lectin_fold. IPR000742. EG-like_dom. IPR013032. EGF-like_CS. IPR002396. Selectin_superfamily. IPR000436. Sushi_SCR_CCP. [Graphical view]
Pfam	PF00059. Lectin_C. 1 hit. PF00084. Sushi. 6 hits. [Graphical view]
PRINTS	PR00343. SELECTIN.
SMART	SM00032. CCP. 6 hits. SM00034. CLECT. 1 hit. SM00181. EGF. 1 hit. [Graphical view]
SUPFAM	SSF56436. C-type_lectin_fold. 1 hit. SSF57535. Complement_control_module. 6 hits.
PROSITE	PS00615. C_TYPE_LECTIN_1. 1 hit. PS50041. C_TYPE_LECTIN_2. 1 hit. PS00022. EGF_1. 1 hit. PS01186. EGF_2. 1 hit. PS50026. EGF_3. 1 hit. PS50923. SUSHI. 6 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q29097_PIG

Accession

Primary (citable) accession number: Q29097

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1996
Last sequence update:	November 1, 1996
Last modified:	April 3, 2013
This is version 88 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)