Q28Y79 (Q28Y79_DROPS) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Glucose-6-phosphate isomerase RuleBase RU000612
EC=5.3.1.9 RuleBase RU000612

Gene names

Name:	GA20931 FlyBase FBgn0080920
Synonyms:	Dpse\GA20931 EMBL EAL26086.1
ORF Names:	Dpse_GA20931 EMBL EAL26086.1

Organism

Drosophila pseudoobscura pseudoobscura (Fruit fly)

Taxonomic identifier

46245 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	559 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-glucose 6-phosphate = D-fructose 6-phosphate. RuleBase RU000612
Pathway	Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. RuleBase RU000612
Subcellular location	Cytoplasm By similarity RuleBase RU003642.
Sequence similarities	Belongs to the GPI family. RuleBase RU000612

Ontologies

Keywords
Biological process	Gluconeogenesis RuleBase RU000612 Glycolysis RuleBase RU000612
Molecular function	Isomerase RuleBase RU000612
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	gluconeogenesis Inferred from electronic annotation. Source: UniProtKB-KW glycolysis Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	glucose-6-phosphate isomerase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q28Y79 [UniParc]. Last modified April 4, 2006. Version 1. Checksum: 452429594BC391D4	FASTA	559	62,242
	10 20 30 40 50 60 MAGTPLPPLN EEPAFKKLQD YYDANHNKIV IKDLFVNDPK RFSKFSLRLR TPNDGEILLD 70 80 90 100 110 120 YSKNRVNDDV WNLLIDLAKS RRVEPARDAM FSGQHINITE NRAVLHTALR NRSADAVLVD 130 140 150 160 170 180 NKDVMPDVRA ELQHMKEFTN KVISGVWRGS TGKQITDVVN IGIGGSDLGP LMVTEALKPY 190 200 210 220 230 240 GKGLYSHFVS NIDGTHMAEV LKKVNYETTL FIIASKTFTT QETITNATSA KTWLLEHAKD 250 260 270 280 290 300 ADAVAKHFVA LSTNKEKVTA FGIDSANMFG FWDWVGGRYS LWSAIGLSIC LSIGFENFEQ 310 320 330 340 350 360 LLDGAHYMDN HFKTSPLDKN APVILALLGV WYSNFYNAET HALLPYDQYL HRFAAYFQQG 370 380 390 400 410 420 DMESNGKFVS KSGKPVKYST GPIVWGEPGT NGQHAFYQLI HQGTRLIPCD FIAPAQTHNP 430 440 450 460 470 480 IAGGKHHKIL LSNFLAQTEA LMAGKTSDEA KQELTKAGLC GNELENLLPH KVFAGNRPTN 490 500 510 520 530 540 SIVVKKVSPF TLGALIALYE HKIFVQGIIW DINSFDQWGV ELGKQLAKAI EPELDTCVEV 550 SSHDSSTNGL INFLKANWK

References

[1]

"Comparative genome sequencing of Drosophila pseudoobscura: chromosomal, gene, and cis-element evolution." Richards S., Liu Y., Bettencourt B.R., Hradecky P., Letovsky S., Nielsen R., Thornton K., Hubisz M.J., Chen R., Meisel R.P., Couronne O., Hua S., Smith M.A., Zhang P., Liu J., Bussemaker H.J., van Batenburg M.F., Howells S.L. , Scherer S.E., Sodergren E., Matthews B.B., Crosby M.A., Schroeder A.J., Ortiz-Barrientos D., Rives C.M., Metzker M.L., Muzny D.M., Scott G., Steffen D., Wheeler D.A., Worley K.C., Havlak P., Durbin K.J., Egan A., Gill R., Hume J., Morgan M.B., Miner G., Hamilton C., Huang Y., Waldron L., Verduzco D., Clerc-Blankenburg K.P., Dubchak I., Noor M.A.F., Anderson W., White K.P., Clark A.G., Schaeffer S.W., Gelbart W.M., Weinstock G.M., Gibbs R.A. Genome Res. 15:1-18(2005) [PubMed: 15632085] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MV2-25 / Tucson 14011-0121.94.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CM000071 Genomic DNA. Translation: EAL26086.1.
RefSeq	XP_001361508.1. XM_001361471.2.
3D structure databases
ProteinModelPortal	Q28Y79.
SMR	Q28Y79. Positions 9-555.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4805043.
GenomeReviews	Gene locus GA20931 in contig CM000071_GR.
KEGG	dpo:Dpse_GA20931.
Organism-specific databases
FlyBase	FBgn0080920. Dpse\GA20931.
Phylogenomic databases
InParanoid	Q28Y79.
OMA	NSLPAWT.
OrthoDB	EOG4JSXMP.
PhylomeDB	Q28Y79.
Family and domain databases
HAMAP	MF_00473. G6P_isomerase. [Tree]
InterPro	IPR001672. G6P_Isomerase. IPR023096. G6P_Isomerase_C. IPR018189. Phosphoglucose_isomerase_CS. [Graphical view]
Gene3D	G3DSA:1.10.1390.10. G6P_Isomerase_C. 1 hit.
KO	K01810.
PANTHER	PTHR11469. G6P_Isomerase. 1 hit.
Pfam	PF00342. PGI. 1 hit. [Graphical view]
PRINTS	PR00662. G6PISOMERASE.
PROSITE	PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit. PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit. PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q28Y79_DROPS

Accession

Primary (citable) accession number: Q28Y79

Entry history

Integrated into UniProtKB/TrEMBL:	April 4, 2006
Last sequence update:	April 4, 2006
Last modified:	January 25, 2012
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)