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Protein

Glycerol-3-phosphate dehydrogenase

Gene

Dpse\GA20935

Organism
Drosophila pseudoobscura pseudoobscura (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol.UniRule annotation

Cofactori

FADUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotationImported

Keywords - Ligandi

CalciumUniRule annotation, FlavoproteinUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glycerol-3-phosphate dehydrogenaseUniRule annotation (EC:1.1.5.3UniRule annotation)
Gene namesi
Name:Dpse\GA20935Imported
ORF Names:Dpse_GA20935Imported, GA20935Imported
OrganismiDrosophila pseudoobscura pseudoobscura (Fruit fly)Imported
Taxonomic identifieri46245 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
ProteomesiUP000001819 Componenti: Chromosome 3

Organism-specific databases

FlyBaseiFBgn0080924. Dpse\GA20935.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi7237.FBpp0278815.

Structurei

3D structure databases

ProteinModelPortaliQ28WL2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.UniRule annotation

Phylogenomic databases

InParanoidiQ28WL2.
KOiK00111.
OMAiKHLTESY.
OrthoDBiEOG74TWZ2.
PhylomeDBiQ28WL2.

Family and domain databases

Gene3Di1.10.238.10. 1 hit.
InterProiIPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
IPR006076. FAD-dep_OxRdtase.
IPR000447. G3P_DH_FAD-dep.
[Graphical view]
PfamiPF01266. DAO. 1 hit.
PF13499. EF-hand_7. 1 hit.
[Graphical view]
PRINTSiPR01001. FADG3PDH.
SMARTiSM00054. EFh. 2 hits.
[Graphical view]
PROSITEiPS00018. EF_HAND_1. 1 hit.
PS50222. EF_HAND_2. 2 hits.
PS00977. FAD_G3PDH_1. 1 hit.
PS00978. FAD_G3PDH_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q28WL2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSRMFKFGV TATSAAVGSV LAAWTLDHWN TPRVVNNAAV APPKRKRTLP
60 70 80 90 100
MRSEQIKSLM SGEEFDVLII GGGATGAGCA LDSVTRGMKT ALVELDDFAS
110 120 130 140 150
GTSSRSTKLI HGGVRYLQKA ILGLDLEQYR MVKEALQERA TMLESAPHLT
160 170 180 190 200
HPLPIMLPVY TWWQVPYFWV GIKAYDFVAG DRNVKSSYYL SKKDALELFP
210 220 230 240 250
MLKKDKLCGA IVYYDGQQDD ARMCLAVALT AARHGATVCN HVEVKELLKK
260 270 280 290 300
DDGTGKQVLC GAKLKDHISG KEFTVKAKCI VNATGPFTDS IRKMDNPSVK
310 320 330 340 350
SICCPSSGVH IVLPGYYSPD QMGLLDPSTS DGRVIFFLPW QRQTIAGTTD
360 370 380 390 400
LPCEITHNPI PTEDEIQFIL KEIKNYLNAD VEVRRGDVLS AWSGIRPLVS
410 420 430 440 450
DPNKDDTQSL ARNHIVHISP SNLITIAGGK WTTYRAMAEH TIDAAIKACN
460 470 480 490 500
LKPERAEAVT SYLKIEGGQG WTPTMYIRLV QDFGLECEVA QHLAKSYGDR
510 520 530 540 550
AFAVSKMASL TGKRWPIIGN RIHPEFPYID AEIRYGVREY ACTAVDMIAR
560 570 580 590 600
RLRLAFLNVQ AAQEALPVIV DIMGEELKWS KEEKERQIKV ATEFLANEMG
610 620 630 640 650
HSVNRTSKER IPIKLSKEEI QTYIKRFQLI DKDKKGYVSI NDIRRGLKSF
660 670 680 690 700
GESDVSGEQL HEILREIDTN MNGQVELDEY LQMMSAIKTG DVAYSRFARM
710 720
AELEEQKHEA ANLKQKISVD RSGGGL
Length:726
Mass (Da):80,901
Last modified:April 4, 2006 - v1
Checksum:iBBB0FEE46F7DE9BB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM000071 Genomic DNA. Translation: EAL26655.1.
RefSeqiXP_001362075.1. XM_001362038.2.

Genome annotation databases

EnsemblMetazoaiFBtr0280377; FBpp0278815; FBgn0080924.
GeneIDi4805720.
KEGGidpo:Dpse_GA20935.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM000071 Genomic DNA. Translation: EAL26655.1.
RefSeqiXP_001362075.1. XM_001362038.2.

3D structure databases

ProteinModelPortaliQ28WL2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7237.FBpp0278815.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0280377; FBpp0278815; FBgn0080924.
GeneIDi4805720.
KEGGidpo:Dpse_GA20935.

Organism-specific databases

FlyBaseiFBgn0080924. Dpse\GA20935.

Phylogenomic databases

InParanoidiQ28WL2.
KOiK00111.
OMAiKHLTESY.
OrthoDBiEOG74TWZ2.
PhylomeDBiQ28WL2.

Family and domain databases

Gene3Di1.10.238.10. 1 hit.
InterProiIPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
IPR006076. FAD-dep_OxRdtase.
IPR000447. G3P_DH_FAD-dep.
[Graphical view]
PfamiPF01266. DAO. 1 hit.
PF13499. EF-hand_7. 1 hit.
[Graphical view]
PRINTSiPR01001. FADG3PDH.
SMARTiSM00054. EFh. 2 hits.
[Graphical view]
PROSITEiPS00018. EF_HAND_1. 1 hit.
PS50222. EF_HAND_2. 2 hits.
PS00977. FAD_G3PDH_1. 1 hit.
PS00978. FAD_G3PDH_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Comparative genome sequencing of Drosophila pseudoobscura: chromosomal, gene, and cis-element evolution."
    Richards S., Liu Y., Bettencourt B.R., Hradecky P., Letovsky S., Nielsen R., Thornton K., Hubisz M.J., Chen R., Meisel R.P., Couronne O., Hua S., Smith M.A., Zhang P., Liu J., Bussemaker H.J., van Batenburg M.F., Howells S.L.
    , Scherer S.E., Sodergren E., Matthews B.B., Crosby M.A., Schroeder A.J., Ortiz-Barrientos D., Rives C.M., Metzker M.L., Muzny D.M., Scott G., Steffen D., Wheeler D.A., Worley K.C., Havlak P., Durbin K.J., Egan A., Gill R., Hume J., Morgan M.B., Miner G., Hamilton C., Huang Y., Waldron L., Verduzco D., Clerc-Blankenburg K.P., Dubchak I., Noor M.A.F., Anderson W., White K.P., Clark A.G., Schaeffer S.W., Gelbart W.M., Weinstock G.M., Gibbs R.A.
    Genome Res. 15:1-18(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MV2-25 / Tucson 14011-0121.94Imported.
  2. "Evolution of genes and genomes on the Drosophila phylogeny."
    Drosophila 12 genomes consortium
    Nature 450:203-218(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MV2-25Imported.

Entry informationi

Entry nameiQ28WL2_DROPS
AccessioniPrimary (citable) accession number: Q28WL2
Entry historyi
Integrated into UniProtKB/TrEMBL: April 4, 2006
Last sequence update: April 4, 2006
Last modified: January 7, 2015
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.