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Q28VQ2 (Q28VQ2_JANSC) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 46. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ferrochelatase HAMAP MF_00323
EC=4.99.1.1 HAMAP MF_00323
Alternative name(s):
Heme synthase HAMAP MF_00323
Protoheme ferro-lyase HAMAP MF_00323
Gene names
Name:hemH HAMAP MF_00323
Ordered Locus Names:Jann_0293
OrganismJannaschia sp. (strain CCS1) [Complete proteome] [HAMAP]
Taxonomic identifier290400 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Jannaschia

Protein attributes

Sequence length370 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the ferrous insertion into protoporphyrin IX By similarity. HAMAP MF_00323

Catalytic activity

Protoheme + 2 H+ = protoporphyrin + Fe2+. HAMAP MF_00323 SAAS SAAS001015

Pathway

Porphyrin metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1. HAMAP MF_00323 SAAS SAAS001015

Subcellular location

Cytoplasm By similarity HAMAP MF_00323.

Sequence similarities

Belongs to the ferrochelatase family. HAMAP MF_00323 RuleBase RU004185

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding2391Iron By similarity HAMAP MF_00323
Metal binding3201Iron By similarity HAMAP MF_00323

Sequences

Sequence LengthMass (Da)Tools
Q28VQ2 [UniParc].

Last modified April 4, 2006. Version 1.
Checksum: 84FBC429DCBF15BE

FASTA37041,618
        10         20         30         40         50         60 
MNMMPAGDAP ALMDTDAPAL TTTDAPALAH APSDHPRVKM GKVGVLLANL GTPDNYDYWS 

        70         80         90        100        110        120 
MRRYLNEFLS DKRVIDYSPW IWQPLLQLVI LSKRPFSSGA AYKSIWNHEA GESPLATITK 

       130        140        150        160        170        180 
DQTAKMKALM ADRYGDDVVV DYCMRYGNPS TKSKVDELVA QGCTKILFFP LYPQYAGATS 

       190        200        210        220        230        240 
ATACDQFFRS LENIKWQPQV RTVEPYYANP LYIDALAQSI ERAYAAMDVK PDLLVTSYHG 

       250        260        270        280        290        300 
VPKRYLMEGD PYHCQCQKTS RLLKERLGWD DTQIVTTFQS KFGPEEWLQP YTVEEVARLA 

       310        320        330        340        350        360 
EKGKKRIAVC APAFSADCIE TLEEINEEIR ESFEEAGGES FTYIPCLNDD DAHMNALATV 

       370 
VDDNLRGWIG

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References

[1]"Complete sequence of chromosome of Jannaschia sp. CCS1."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Chertkov O., Saunders E., Schmutz J., Larimer F. expand/collapse author list , Land M., Kyrpides N., Lykidis A., Moran M.A., Belas R., Ye W., Buchan A., Gonzalez J.M., Schell M.A., Richardson P.
Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CCS1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000264 Genomic DNA. Translation: ABD53210.1.
RefSeqYP_508235.1. NC_007802.1.

3D structure databases

ProteinModelPortalQ28VQ2.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ28VQ2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3932731.
GenomeReviewsGene locus Jann_0293 in contig CP000264_GR.
KEGGjan:Jann_0293.
PATRIC22144178. VBIJanSp43325_0366.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0276.
HOGENOMHBG697135.
OMAIRPAKSA.
PhylomeDBQ28VQ2.
ProtClustDBPRK00035.

Family and domain databases

HAMAPMF_00323. Ferrochelatase.
[Tree]
InterProIPR001015. Ferrochelatase.
[Graphical view]
KOK01772.
PANTHERPTHR11108. Ferrochelatase. 1 hit.
PfamPF00762. Ferrochelatase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00109. HemH. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ28VQ2_JANSC
AccessionPrimary (citable) accession number: Q28VQ2
Entry history
Integrated into UniProtKB/TrEMBL: April 4, 2006
Last sequence update: April 4, 2006
Last modified: December 14, 2011
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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