ID   ADEC1_JANSC             Reviewed;         594 AA.
AC   Q28VK7;
DT   26-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT   26-JUN-2007, sequence version 2.
DT   04-NOV-2008, entry version 15.
DE   RecName: Full=Adenine deaminase 1;
DE            Short=Adenase 1;
DE            Short=Adenine aminase 1;
DE            EC=3.5.4.2;
GN   Name=ade1; OrderedLocusNames=Jann_0338;
OS   Jannaschia sp. (strain CCS1).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales;
OC   Rhodobacteraceae; Jannaschia.
OX   NCBI_TaxID=290400;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Pitluck S., Brettin T.,
RA   Bruce D., Han C., Tapia R., Gilna P., Chertkov O., Saunders E.,
RA   Schmutz J., Larimer F., Land M., Kyrpides N., Lykidis A., Moran M.A.,
RA   Belas R., Ye W., Buchan A., Gonzalez J.M., Schell M.A., Richardson P.;
RT   "Complete sequence of chromosome of Jannaschia sp. CCS1.";
RL   Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: Adenine + H(2)O = hypoxanthine + NH(3).
CC   -!- COFACTOR: Manganese (By similarity).
CC   -!- SIMILARITY: Belongs to the adenine deaminase family.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; CP000264; ABD53255.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; YP_508280.1; -.
DR   GeneID; 3932779; -.
DR   GenomeReviews; CP000264_GR; Jann_0338.
DR   KEGG; jan:Jann_0338; -.
DR   HOGENOM; Q28VK7; -.
DR   BioCyc; JSP290400:JANN_0338-MON; -.
DR   GO; GO:0000034; F:adenine deaminase activity; IEA:HAMAP.
DR   GO; GO:0030145; F:manganese ion binding; IEA:UniProtKB-KW.
DR   HAMAP; MF_01518; -; 1.
DR   InterPro; IPR006680; Amidohydro_1.
DR   Pfam; PF01979; Amidohydro_1; 1.
DR   ProDom; PD001248; Amidohydro_like; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Hydrolase; Manganese.
FT   CHAIN         1    594       Adenine deaminase 1.
FT                                /FTId=PRO_0000292382.
SQ   SEQUENCE   594 AA;  63426 MW;  067D61344E0AF98F CRC64;
     MEPTPFPSWQ DVASALVATA AGRAPADLVI RGAKVVLVQT REVMDGWDVA IKHGRFAYVG
     PDASHCIGED TQVEELSGHY LIPGLCDGHM HIESGMLTPA EFTRAVIPHG TTSMFTDPHE
     IANVFGLRGV RLMHDEALLQ PINVFTQMPS CAPSAPGLET TGFEIGPDDV SEAMAWPGIV
     GLGEMMNFPG VVNGSQQMLA EIAATQAAGK TVGGHYASPD LGPAFHAYAA GGPADDHEGT
     SETDAMARMR QGMRSMIRLG SAWYDIESQI TAITERGLDP RNMIICTDDC FAKTLVEDGH
     MNRAVRHAID CGCDPLIALQ MATINTATHF GLEREIGQIA PGRRADMIVT RDLRTLPIEV
     VYARGQRVAQ FGECLVECPH LDWPTDTRHS VNLGKSLTAA DFEIRSDAAE VTANVIGVVE
     NQAPTKALTQ TLPVRHGVVE PDGIAQIALV ERHRGTGGVT NAFVSGFGYG PGMAMASTVA
     HDSHHMIVVG TDRAMMAKAA MRLGEVGGGI TLWQDGTERA LVELPIAGLM SDRPATEVAA
     KVTQLVEAME AAGCTLNNAY MQHSLLALVV IPELRISDLG LVDVRTFELT PVLP
//