Q28VK7 (ADEC1_JANSC) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Adenine deaminase 1
Short name=Adenase 1
Short name=Adenine aminase 1
EC=3.5.4.2

Gene names

Name:	ade1
Ordered Locus Names:	Jann_0338

Organism

Jannaschia sp. (strain CCS1) [Complete proteome] [HAMAP]

Taxonomic identifier

290400 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Jannaschia

Protein attributes

Sequence length	594 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Adenine + H2O = hypoxanthine + NH3. HAMAP MF_01518
Cofactor	Manganese By similarity. HAMAP MF_01518
Sequence similarities	Belongs to the adenine deaminase family.
Sequence caution	The sequence ABD53255.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Ligand	Manganese
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	adenine catabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	adenine deaminase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 594	594	Adenine deaminase 1 HAMAP MF_01518		PRO_0000292382

Sequences

	Sequence		Length	Mass (Da)
	Q28VK7 [UniParc]. Last modified June 26, 2007. Version 2. Checksum: 067D61344E0AF98F	FASTA	594	63,426
	10 20 30 40 50 60 MEPTPFPSWQ DVASALVATA AGRAPADLVI RGAKVVLVQT REVMDGWDVA IKHGRFAYVG 70 80 90 100 110 120 PDASHCIGED TQVEELSGHY LIPGLCDGHM HIESGMLTPA EFTRAVIPHG TTSMFTDPHE 130 140 150 160 170 180 IANVFGLRGV RLMHDEALLQ PINVFTQMPS CAPSAPGLET TGFEIGPDDV SEAMAWPGIV 190 200 210 220 230 240 GLGEMMNFPG VVNGSQQMLA EIAATQAAGK TVGGHYASPD LGPAFHAYAA GGPADDHEGT 250 260 270 280 290 300 SETDAMARMR QGMRSMIRLG SAWYDIESQI TAITERGLDP RNMIICTDDC FAKTLVEDGH 310 320 330 340 350 360 MNRAVRHAID CGCDPLIALQ MATINTATHF GLEREIGQIA PGRRADMIVT RDLRTLPIEV 370 380 390 400 410 420 VYARGQRVAQ FGECLVECPH LDWPTDTRHS VNLGKSLTAA DFEIRSDAAE VTANVIGVVE 430 440 450 460 470 480 NQAPTKALTQ TLPVRHGVVE PDGIAQIALV ERHRGTGGVT NAFVSGFGYG PGMAMASTVA 490 500 510 520 530 540 HDSHHMIVVG TDRAMMAKAA MRLGEVGGGI TLWQDGTERA LVELPIAGLM SDRPATEVAA 550 560 570 580 590 KVTQLVEAME AAGCTLNNAY MQHSLLALVV IPELRISDLG LVDVRTFELT PVLP

References

[1]

"Complete sequence of chromosome of Jannaschia sp. CCS1." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Chertkov O., Saunders E., Schmutz J., Larimer F. , Land M., Kyrpides N., Lykidis A., Moran M.A., Belas R., Ye W., Buchan A., Gonzalez J.M., Schell M.A., Richardson P. Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CCS1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000264 Genomic DNA. Translation: ABD53255.1. Different initiation.
RefSeq	YP_508280.1. NC_007802.1.
3D structure databases
ProteinModelPortal	Q28VK7.
ModBase	Search...
Protein-protein interaction databases
STRING	Q28VK7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3932779.
GenomeReviews	Gene locus Jann_0338 in contig CP000264_GR.
KEGG	jan:Jann_0338.
PATRIC	22144278. VBIJanSp43325_0414.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1001.
HOGENOM	HBG725357.
ProtClustDB	CLSK862922.
Enzyme and pathway databases
BioCyc	JSP290400:JANN_0338-MONOMER.
Family and domain databases
HAMAP	MF_01518. Adenine_deamin. [Tree]
InterPro	IPR006679. Adenine_deam. IPR006680. Amidohydro_1. IPR011059. Metal-dep_hydrolase_composite. [Graphical view]
KO	K01486.
Pfam	PF01979. Amidohydro_1. 1 hit. [Graphical view]
SUPFAM	SSF51338. Metalo_hydrolase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ADEC1_JANSC

Accession

Primary (citable) accession number: Q28VK7

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 26, 2007
Last sequence update:	June 26, 2007
Last modified:	January 25, 2012
This is version 29 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program