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Q28VK7 (ADEC1_JANSC) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Adenine deaminase 1

Short name=Adenase 1
Short name=Adenine aminase 1
EC=3.5.4.2
Gene names
Name:ade1
Ordered Locus Names:Jann_0338
OrganismJannaschia sp. (strain CCS1) [Complete proteome] [HAMAP]
Taxonomic identifier290400 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeJannaschia

Protein attributes

Sequence length594 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Adenine + H2O = hypoxanthine + NH3. HAMAP MF_01518

Cofactor

Manganese By similarity. HAMAP MF_01518

Sequence similarities

Belongs to the adenine deaminase family.

Sequence caution

The sequence ABD53255.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   LigandManganese
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processadenine catabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular functionadenine deaminase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 594594Adenine deaminase 1 HAMAP MF_01518
PRO_0000292382

Sequences

Sequence LengthMass (Da)Tools
Q28VK7 [UniParc].

Last modified June 26, 2007. Version 2.
Checksum: 067D61344E0AF98F

FASTA59463,426
        10         20         30         40         50         60 
MEPTPFPSWQ DVASALVATA AGRAPADLVI RGAKVVLVQT REVMDGWDVA IKHGRFAYVG 

        70         80         90        100        110        120 
PDASHCIGED TQVEELSGHY LIPGLCDGHM HIESGMLTPA EFTRAVIPHG TTSMFTDPHE 

       130        140        150        160        170        180 
IANVFGLRGV RLMHDEALLQ PINVFTQMPS CAPSAPGLET TGFEIGPDDV SEAMAWPGIV 

       190        200        210        220        230        240 
GLGEMMNFPG VVNGSQQMLA EIAATQAAGK TVGGHYASPD LGPAFHAYAA GGPADDHEGT 

       250        260        270        280        290        300 
SETDAMARMR QGMRSMIRLG SAWYDIESQI TAITERGLDP RNMIICTDDC FAKTLVEDGH 

       310        320        330        340        350        360 
MNRAVRHAID CGCDPLIALQ MATINTATHF GLEREIGQIA PGRRADMIVT RDLRTLPIEV 

       370        380        390        400        410        420 
VYARGQRVAQ FGECLVECPH LDWPTDTRHS VNLGKSLTAA DFEIRSDAAE VTANVIGVVE 

       430        440        450        460        470        480 
NQAPTKALTQ TLPVRHGVVE PDGIAQIALV ERHRGTGGVT NAFVSGFGYG PGMAMASTVA 

       490        500        510        520        530        540 
HDSHHMIVVG TDRAMMAKAA MRLGEVGGGI TLWQDGTERA LVELPIAGLM SDRPATEVAA 

       550        560        570        580        590 
KVTQLVEAME AAGCTLNNAY MQHSLLALVV IPELRISDLG LVDVRTFELT PVLP 

« Hide

References

[1]"Complete sequence of chromosome of Jannaschia sp. CCS1."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Chertkov O., Saunders E., Schmutz J., Larimer F. expand/collapse author list , Land M., Kyrpides N., Lykidis A., Moran M.A., Belas R., Ye W., Buchan A., Gonzalez J.M., Schell M.A., Richardson P.
Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CCS1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000264 Genomic DNA. Translation: ABD53255.1. Different initiation.
RefSeqYP_508280.1. NC_007802.1.

3D structure databases

ProteinModelPortalQ28VK7.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ28VK7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3932779.
GenomeReviewsGene locus Jann_0338 in contig CP000264_GR.
KEGGjan:Jann_0338.
PATRIC22144278. VBIJanSp43325_0414.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1001.
HOGENOMHBG725357.
ProtClustDBCLSK862922.

Enzyme and pathway databases

BioCycJSP290400:JANN_0338-MONOMER.

Family and domain databases

HAMAPMF_01518. Adenine_deamin.
[Tree]
InterProIPR006679. Adenine_deam.
IPR006680. Amidohydro_1.
IPR011059. Metal-dep_hydrolase_composite.
[Graphical view]
KOK01486.
PfamPF01979. Amidohydro_1. 1 hit.
[Graphical view]
SUPFAMSSF51338. Metalo_hydrolase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameADEC1_JANSC
AccessionPrimary (citable) accession number: Q28VK7
Entry history
Integrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: June 26, 2007
Last modified: January 25, 2012
This is version 29 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families