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Protein

Adenine deaminase 1

Gene

ade1

Organism
Jannaschia sp. (strain CCS1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Adenine + H2O = hypoxanthine + NH3.UniRule annotation

Cofactori

Mn2+UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Manganese

Names & Taxonomyi

Protein namesi
Recommended name:
Adenine deaminase 1UniRule annotation (EC:3.5.4.2UniRule annotation)
Short name:
Adenase 1UniRule annotation
Short name:
Adenine aminase 1UniRule annotation
Gene namesi
Name:ade1UniRule annotation
Ordered Locus Names:Jann_0338
OrganismiJannaschia sp. (strain CCS1)
Taxonomic identifieri290400 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeJannaschia
Proteomesi
  • UP000008326 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002923821 – 594Adenine deaminase 1Add BLAST594

Interactioni

Protein-protein interaction databases

STRINGi290400.Jann_0338.

Structurei

3D structure databases

ProteinModelPortaliQ28VK7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the adenine deaminase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CPN. Bacteria.
COG1001. LUCA.
HOGENOMiHOG000276949.
KOiK01486.
OrthoDBiPOG091H00I8.

Family and domain databases

CDDicd01295. AdeC. 1 hit.
Gene3Di2.30.40.10. 2 hits.
HAMAPiMF_01518. Adenine_deamin. 1 hit.
InterProiIPR006679. Adenine_deam.
IPR026912. Adenine_deam_C.
IPR006680. Amidohydro-rel.
IPR011059. Metal-dep_hydrolase_composite.
IPR032466. Metal_Hydrolase.
[Graphical view]
PfamiPF13382. Adenine_deam_C. 1 hit.
PF01979. Amidohydro_1. 1 hit.
[Graphical view]
SUPFAMiSSF51338. SSF51338. 2 hits.
SSF51556. SSF51556. 1 hit.

Sequencei

Sequence statusi: Complete.

Q28VK7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEPTPFPSWQ DVASALVATA AGRAPADLVI RGAKVVLVQT REVMDGWDVA
60 70 80 90 100
IKHGRFAYVG PDASHCIGED TQVEELSGHY LIPGLCDGHM HIESGMLTPA
110 120 130 140 150
EFTRAVIPHG TTSMFTDPHE IANVFGLRGV RLMHDEALLQ PINVFTQMPS
160 170 180 190 200
CAPSAPGLET TGFEIGPDDV SEAMAWPGIV GLGEMMNFPG VVNGSQQMLA
210 220 230 240 250
EIAATQAAGK TVGGHYASPD LGPAFHAYAA GGPADDHEGT SETDAMARMR
260 270 280 290 300
QGMRSMIRLG SAWYDIESQI TAITERGLDP RNMIICTDDC FAKTLVEDGH
310 320 330 340 350
MNRAVRHAID CGCDPLIALQ MATINTATHF GLEREIGQIA PGRRADMIVT
360 370 380 390 400
RDLRTLPIEV VYARGQRVAQ FGECLVECPH LDWPTDTRHS VNLGKSLTAA
410 420 430 440 450
DFEIRSDAAE VTANVIGVVE NQAPTKALTQ TLPVRHGVVE PDGIAQIALV
460 470 480 490 500
ERHRGTGGVT NAFVSGFGYG PGMAMASTVA HDSHHMIVVG TDRAMMAKAA
510 520 530 540 550
MRLGEVGGGI TLWQDGTERA LVELPIAGLM SDRPATEVAA KVTQLVEAME
560 570 580 590
AAGCTLNNAY MQHSLLALVV IPELRISDLG LVDVRTFELT PVLP
Length:594
Mass (Da):63,426
Last modified:June 26, 2007 - v2
Checksum:i067D61344E0AF98F
GO

Sequence cautioni

The sequence ABD53255 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000264 Genomic DNA. Translation: ABD53255.1. Different initiation.
RefSeqiWP_044006214.1. NC_007802.1.

Genome annotation databases

EnsemblBacteriaiABD53255; ABD53255; Jann_0338.
KEGGijan:Jann_0338.
PATRICi22144278. VBIJanSp43325_0414.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000264 Genomic DNA. Translation: ABD53255.1. Different initiation.
RefSeqiWP_044006214.1. NC_007802.1.

3D structure databases

ProteinModelPortaliQ28VK7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi290400.Jann_0338.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABD53255; ABD53255; Jann_0338.
KEGGijan:Jann_0338.
PATRICi22144278. VBIJanSp43325_0414.

Phylogenomic databases

eggNOGiENOG4105CPN. Bacteria.
COG1001. LUCA.
HOGENOMiHOG000276949.
KOiK01486.
OrthoDBiPOG091H00I8.

Family and domain databases

CDDicd01295. AdeC. 1 hit.
Gene3Di2.30.40.10. 2 hits.
HAMAPiMF_01518. Adenine_deamin. 1 hit.
InterProiIPR006679. Adenine_deam.
IPR026912. Adenine_deam_C.
IPR006680. Amidohydro-rel.
IPR011059. Metal-dep_hydrolase_composite.
IPR032466. Metal_Hydrolase.
[Graphical view]
PfamiPF13382. Adenine_deam_C. 1 hit.
PF01979. Amidohydro_1. 1 hit.
[Graphical view]
SUPFAMiSSF51338. SSF51338. 2 hits.
SSF51556. SSF51556. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiADEC1_JANSC
AccessioniPrimary (citable) accession number: Q28VK7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: June 26, 2007
Last modified: November 2, 2016
This is version 53 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.