Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q28SE4 (Q28SE4_JANSC) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 41. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Probable L-aspartate dehydrogenase HAMAP MF_01265
EC=1.4.1.21 HAMAP MF_01265
Gene names
Name:nadX HAMAP MF_01265
Ordered Locus Names:Jann_1451
OrganismJannaschia sp. (strain CCS1) [Complete proteome] [HAMAP]
Taxonomic identifier290400 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Jannaschia

Protein attributes

Sequence length253 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate By similarity. HAMAP MF_01265

Catalytic activity

L-aspartate + H2O + NAD(P)+ = oxaloacetate + NH3 + NAD(P)H. HAMAP MF_01265

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; iminoaspartate from L-aspartate (dehydrogenase route): step 1/1. HAMAP MF_01265

Miscellaneous

The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia By similarity. HAMAP MF_01265

Sequence similarities

Belongs to the L-aspartate dehydrogenase family. HAMAP MF_01265

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site2051 By similarity HAMAP MF_01265
Binding site1091NAD; via amide nitrogen By similarity HAMAP MF_01265
Binding site1751NAD By similarity HAMAP MF_01265

Sequences

Sequence LengthMass (Da)Tools
Q28SE4 [UniParc].

Last modified April 4, 2006. Version 1.
Checksum: 0ED80FE1BCF24F74

FASTA25325,575
        10         20         30         40         50         60 
MRVGIIGKGA IAGYVTAQIA AMADVSIAAR VLRQPVDGAV TDVADLPALD LLIDCAGHAG 

        70         80         90        100        110        120 
LSAHGPQALA REIDVLTLSL GALADAALSQ RLAEAATQGA ARLHLASGAI GALDALRAAK 

       130        140        150        160        170        180 
AGGLTRVTYT GRKPPAGWRG SPAEDVLDLS SLTEATPHFE GSARNAALRY PKNANVAAAV 

       190        200        210        220        230        240 
ALAGLGFDDT QVALIADPNA AGNIHEITAE GTFGQLAFTI TGNSLPDNPR SSALAAMSAI 

       250 
AAIRQLHDPI RFA

« Hide

References

[1]"Complete sequence of chromosome of Jannaschia sp. CCS1."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Chertkov O., Saunders E., Schmutz J., Larimer F. expand/collapse author list , Land M., Kyrpides N., Lykidis A., Moran M.A., Belas R., Ye W., Buchan A., Gonzalez J.M., Schell M.A., Richardson P.
Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CCS1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000264 Genomic DNA. Translation: ABD54368.1.
RefSeqYP_509393.1. NC_007802.1.

3D structure databases

ProteinModelPortalQ28SE4.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ28SE4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3933898.
GenomeReviewsGene locus Jann_1451 in contig CP000264_GR.
KEGGjan:Jann_1451.
PATRIC22146608. VBIJanSp43325_1575.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1712.
HOGENOMHBG649642.
OMAECAGHSA.
ProtClustDBPRK13303.

Family and domain databases

HAMAPMF_01265. NadX.
[Tree]
InterProIPR005106. Asp/hSer_DH_NAD-bd.
IPR002811. Asp_DH.
IPR011182. Asp_DH_NAD_syn.
IPR020626. Asp_DH_NAD_syn_prok.
[Graphical view]
KOK06989.
PfamPF01958. DUF108. 1 hit.
PF03447. NAD_binding_3. 1 hit.
[Graphical view]
PIRSFPIRSF005227. Asp_dh_NAD_syn. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ28SE4_JANSC
AccessionPrimary (citable) accession number: Q28SE4
Entry history
Integrated into UniProtKB/TrEMBL: April 4, 2006
Last sequence update: April 4, 2006
Last modified: December 14, 2011
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info