Q28SA3 (Q28SA3_JANSC) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Choline dehydrogenase RuleBase RU003969
EC=1.1.99.1 RuleBase RU003969

Gene names

Ordered Locus Names:

Jann_1492

Organism

Jannaschia sp. (strain CCS1) [Complete proteome] [HAMAP]

Taxonomic identifier

290400 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Jannaschia

Protein attributes

Sequence length	556 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine By similarity. SAAS SAAS007867
Catalytic activity	Choline + acceptor = betaine aldehyde + reduced acceptor. RuleBase RU003969 SAAS SAAS007867
Cofactor	FAD By similarity. SAAS SAAS007867 RuleBase RU003968
Pathway	Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine aldehyde from choline (cytochrome c reductase route): step 1/1. RuleBase RU003969 SAAS SAAS007867
Sequence similarities	Belongs to the GMC oxidoreductase family. RuleBase RU003968

Ontologies

Keywords
Ligand	FAD SAAS SAAS011533 Flavoprotein SAAS SAAS011533 RuleBase RU003968
Molecular function	Oxidoreductase SAAS SAAS007867
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycine betaine biosynthetic process from choline Inferred from electronic annotation. Source: InterPro
Molecular function	choline dehydrogenase activity Inferred from electronic annotation. Source: EC flavin adenine dinucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q28SA3 [UniParc]. Last modified April 4, 2006. Version 1. Checksum: 4BAEE97BAD278E17	FASTA	556	60,731
	10 20 30 40 50 60 MEADYVVIGA GSAGCAVTYR LAEAGKSVLV VEHGGSDWGP FINMPAALSY PMGMKRYDWG 70 80 90 100 110 120 YVTEPEPHMN NRVMACPRGK VVGGSSSING MIYVRGHARD FDTWAEMGAD GWSYADVLPY 130 140 150 160 170 180 FKRAETWHGD AGEPAFRGSD GPVHVTRGTR KNPLYQAFID AGMQAGYGAT DDYNGYRQEG 190 200 210 220 230 240 FGAFEMTVYK GKRWSAASAY LRPALAKPNC DMVRGLVQRI EFKEGRATGV RLADGSLIRV 250 260 270 280 290 300 RCEVVLCAGA INSPKILMLS GIGPAKHLAE HGISVVADRA GVGQNLQDHL EMYIQYAASK 310 320 330 340 350 360 PVSIAPYWSL WGKAAVGAQW LFTKTGLGAT NNFESCGFIR SSAGVEYPDI QYHFLPIAIR 370 380 390 400 410 420 YDGQMPPGGH GFQAHTGPMR SPSRGEITLR SQDPAQAPKI QFNYMSHEKD WRDFRRAIRL 430 440 450 460 470 480 TREIFATEPM AEYVDHEIQP GDAAQFDDAL DAVIREHAES AYHPCGTARV GQRNDPMSVV 490 500 510 520 530 540 DPQTSVIGVS SLRVADSSIF PLIPNGNLNA PSIMVGEKAA DHILGRRVPA ENLTPWIAPD 550 WQSTQRESHA VKAAAE

References

[1]

"Complete sequence of chromosome of Jannaschia sp. CCS1." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Chertkov O., Saunders E., Schmutz J., Larimer F. , Land M., Kyrpides N., Lykidis A., Moran M.A., Belas R., Ye W., Buchan A., Gonzalez J.M., Schell M.A., Richardson P. Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CCS1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000264 Genomic DNA. Translation: ABD54409.1.
RefSeq	YP_509434.1. NC_007802.1.
3D structure databases
ProteinModelPortal	Q28SA3.
ModBase	Search...
Protein-protein interaction databases
STRING	Q28SA3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3933939.
GenomeReviews	Gene locus Jann_1492 in contig CP000264_GR.
KEGG	jan:Jann_1492.
PATRIC	22146694. VBIJanSp43325_1618.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2303.
HOGENOM	HBG734713.
OMA	GPFIQMP.
PhylomeDB	Q28SA3.
ProtClustDB	PRK02106.
Family and domain databases
InterPro	IPR011533. Choline_dehydrogenase. IPR012132. GMC_OxRdtase. IPR000172. GMC_OxRdtase_N. IPR007867. GMC_OxRtase_C. [Graphical view]
KO	K00108.
Pfam	PF05199. GMC_oxred_C. 1 hit. PF00732. GMC_oxred_N. 1 hit. [Graphical view]
PIRSF	PIRSF000137. Alcohol_oxidase. 1 hit.
TIGRFAMs	TIGR01810. BetA. 1 hit.
PROSITE	PS00623. GMC_OXRED_1. 1 hit. PS00624. GMC_OXRED_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q28SA3_JANSC

Accession

Primary (citable) accession number: Q28SA3

Entry history

Integrated into UniProtKB/TrEMBL:	April 4, 2006
Last sequence update:	April 4, 2006
Last modified:	December 14, 2011
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)