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Q28S88 (SYR_JANSC) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:Jann_1507
OrganismJannaschia sp. (strain CCS1) [Complete proteome] [HAMAP]
Taxonomic identifier290400 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeJannaschia

Protein attributes

Sequence length575 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 575575Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_0000242033

Regions

Motif131 – 14111"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
Q28S88 [UniParc].

Last modified April 4, 2006. Version 1.
Checksum: 35AD4B1913885F38

FASTA57562,834
        10         20         30         40         50         60 
MTLFAEIRDT VLAAIDTLVA DNVLPSGLEM RAVTVEPPRD ASHGDMATNA AMVLAKPAGM 

        70         80         90        100        110        120 
KPRDIAEALA AKLADDARID TVDVAGPGFL NLRLSGDVWR GVIADALTQG EAYGRSKIGA 

       130        140        150        160        170        180 
GKRVNVEYVS ANPTGPLHVG HTRGAVFGDA LASLLDVAGY DVTREYYIND GGAQVDVLVR 

       190        200        210        220        230        240 
SVYLRYLEAH GQDVAFEDGT YPGDYLIDVG QALKDKVGDA FVDKGEQFWL AEIREFATEQ 

       250        260        270        280        290        300 
MMDLIRKDLA LLGVEMDVFY SEKSLYGTGR IEAAIDDLRG KGLIYEGYLE PPKGKTPEDW 

       310        320        330        340        350        360 
EPREQTLFKS TEHGDDVDRP VMKSDGSWTY FAPDIAYHFD KVSRGFDELI DVFGADHGGY 

       370        380        390        400        410        420 
VKRMKAAVSA LSGGDVPLDV KLTQLVKLRR GDEELKMSKR AGTFVTLADV VEMVGADVTR 

       430        440        450        460        470        480 
FHMLTRKNDA PLDFDVDKVR EQSKDNPVWY VQYAHARIKS VLRKAEEAGM SPDPANLNAV 

       490        500        510        520        530        540 
NDPAELALAA KIAEYPRLIE IAAKGNEPHR VAFYLFDLAS DFHGLWNKGN AETHLRFFQD 

       550        560        570 
DDPSATSGKL CLISAVAIVI SNGLGILGVT PVDQM 

« Hide

References

[1]"Complete sequence of chromosome of Jannaschia sp. CCS1."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Chertkov O., Saunders E., Schmutz J., Larimer F. expand/collapse author list , Land M., Kyrpides N., Lykidis A., Moran M.A., Belas R., Ye W., Buchan A., Gonzalez J.M., Schell M.A., Richardson P.
Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CCS1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000264 Genomic DNA. Translation: ABD54424.1.
RefSeqYP_509449.1. NC_007802.1.

3D structure databases

ProteinModelPortalQ28S88.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING290400.Jann_1507.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABD54424; ABD54424; Jann_1507.
GeneID3933954.
KEGGjan:Jann_1507.
PATRIC22146724. VBIJanSp43325_1633.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247214.
KOK01887.
OMANPNGPLH.
OrthoDBEOG6JB13C.
ProtClustDBPRK01611.

Enzyme and pathway databases

BioCycJSP290400:GI1R-1518-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_JANSC
AccessionPrimary (citable) accession number: Q28S88
Entry history
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: April 4, 2006
Last modified: April 16, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries