Q28S37 (Q28S37_JANSC) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Error-prone DNA polymerase HAMAP MF_01902
EC=2.7.7.7 HAMAP MF_01902

Gene names

Name:	dnaE2 HAMAP MF_01902
Ordered Locus Names:	Jann_1558

Organism

Jannaschia sp. (strain CCS1) [Complete proteome] [HAMAP]

Taxonomic identifier

290400 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Jannaschia

Protein attributes

Sequence length	1097 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase By similarity. HAMAP MF_01902
Catalytic activity	Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). HAMAP MF_01902 SAAS SAAS004013
Subcellular location	Cytoplasm By similarity HAMAP MF_01902 SAAS SAAS004013.
Sequence similarities	Belongs to the DNA polymerase type-C family. DnaE2 subfamily. HAMAP MF_01902

Ontologies

Keywords
Biological process	DNA damage DNA repair HAMAP MF_01902 SAAS SAAS004013 DNA replication HAMAP MF_01902 SAAS SAAS004013
Cellular component	Cytoplasm HAMAP MF_01902 SAAS SAAS004013
Molecular function	DNA-directed DNA polymerase HAMAP MF_01902 SAAS SAAS004013 Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA repair Inferred from electronic annotation. Source: HAMAP DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	3'-5' exonuclease activity Inferred from electronic annotation. Source: InterPro DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed DNA polymerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q28S37 [UniParc]. Last modified April 4, 2006. Version 1. Checksum: 9EDBEFC2896ED394	FASTA	1,097	123,185
	10 20 30 40 50 60 MDNQRPRRTI EEGGFKPNPK ADYVELGLTT CFSFLHGASD AVDLATTAHG LGYDKLGCAD 70 80 90 100 110 120 LNTMAGVVRL HAEALKAQIT PVIGCRLRLV TGEDFLAYPR DRAAYGRLCT LLSKGKMTDV 130 140 150 160 170 180 DGAWQAKGAC DITLDDLAGH SKDVQLIALP GPRLDHFEAG FKRLIRALPT LRHIAVSYLY 190 200 210 220 230 240 EGDDRARINR LDRLAQAHGL GIMATNDVRY HAPDRRPLQD VMTCILHKTT IQKAGFLLNA 250 260 270 280 290 300 NAERHLKSPA QMIQLFAQWP HAIRATRAIA DACTFDLREL AYEYPKETVP EGRTPQGYLE 310 320 330 340 350 360 ELTWKGAARR YPDGIPDAIS TTLRKELALI KKMDIPQYFL TIEQIVDYAR HKCDPPILCQ 370 380 390 400 410 420 GRGSAANSAV CYVLGITAVD PNTNDLLFER FISEERKEPP DIDVDFEHER REEVIQHIYN 430 440 450 460 470 480 RYGRDRAALC ATVIHYRPRM AVREVGKVMG LSEDITSALA KTIWGSWGRE VGAREAAEAG 490 500 510 520 530 540 IDLKDPLMAR TIKLADQMIG MPRHLGQHVG GFILTEKKLN ETVPIGNGAM ADRTFIEWDK 550 560 570 580 590 600 DDIDELRILK VDILALGMLT CIRKAFDLIK AHYGRTLTLA SIEQGDRATY DMLCKGDSLG 610 620 630 640 650 660 VFQVESRAQM NMLPRLKPRE FYDLVIQVAI VRPGPIQGDM VHPYLRRRAG KEPEDYPSPK 670 680 690 700 710 720 PPHDPEELRK VLSRTKGVPI FQEQAMKLAM VAAEFSPDEA NQLRKAMATF RSKGTIGELE 730 740 750 760 770 780 EKMVSRMINR GYDPEFAHRC FNQIKGFGDY GFPESHAASF AHLVYISSWI KCHYPDVFCA 790 800 810 820 830 840 ALLNSQPMGF YAPAQIVRDA REHGVIVRAA DVNYSGWDTT LEPVGQGQFA VRLGQRQIDG 850 860 870 880 890 900 MRQDVADRIV TARHTPFTDL IDLRQRAQTD AGSLRKLAAA DAMRSMMLDR RQALWETRAL 910 920 930 940 950 960 HDAQDLPLFA EQKDEGDEIR FDLPEMPICE HVVADYQTTR LSLKAHPMSF LRKSMERQGY 970 980 990 1000 1010 1020 HHTGALAHMR NGQSVKLAGI VLIRQRPGSA KGVCFITVED EIGVANLVVW PKVMEAFRKV 1030 1040 1050 1060 1070 1080 IMGARIIDVR GVVQRSDDVI HVVAHHLADR SDALERLSND IMEPPLARAD EVKRALPHGT 1090 HGHPRNVRVI PKSRDFH

References

[1]

"Complete sequence of chromosome of Jannaschia sp. CCS1." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Chertkov O., Saunders E., Schmutz J., Larimer F. , Land M., Kyrpides N., Lykidis A., Moran M.A., Belas R., Ye W., Buchan A., Gonzalez J.M., Schell M.A., Richardson P. Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CCS1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000264 Genomic DNA. Translation: ABD54475.1.
RefSeq	YP_509500.1. NC_007802.1.
3D structure databases
ProteinModelPortal	Q28S37.
ModBase	Search...
Protein-protein interaction databases
STRING	Q28S37.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3934006.
GenomeReviews	Gene locus Jann_1558 in contig CP000264_GR.
KEGG	jan:Jann_1558.
PATRIC	22146818. VBIJanSp43325_1679.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0587.
HOGENOM	HBG734490.
OMA	LATNRNG.
ProtClustDB	CLSK773035.
Family and domain databases
HAMAP	MF_01902. DNApol_error_prone. [Tree]
InterPro	IPR011708. DNA_pol3_alpha. IPR023073. DNA_pol_error_prone. IPR012340. NA-bd_OB-fold. IPR004365. NA-bd_OB_tRNA-helicase. IPR004013. PHP_C. IPR003141. Pol/His_phosphatase_N. IPR004805. PolC_alpha. [Graphical view]
Gene3D	G3DSA:2.40.50.140. OB_NA_bd_sub. 1 hit.
KO	K14162.
Pfam	PF07733. DNA_pol3_alpha. 1 hit. PF02811. PHP. 1 hit. PF01336. tRNA_anti. 1 hit. [Graphical view]
SMART	SM00481. POLIIIAc. 1 hit. [Graphical view]
TIGRFAMs	TIGR00594. Polc. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q28S37_JANSC

Accession

Primary (citable) accession number: Q28S37

Entry history

Integrated into UniProtKB/TrEMBL:	April 4, 2006
Last sequence update:	April 4, 2006
Last modified:	December 14, 2011
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)