ID   Q28RS1_JANSC            Unreviewed;       731 AA.
AC   Q28RS1;
DT   04-APR-2006, integrated into UniProtKB/TrEMBL.
DT   04-APR-2006, sequence version 1.
DT   27-MAR-2024, entry version 84.
DE   SubName: Full=Adenylate/guanylate cyclase {ECO:0000313|EMBL:ABD54591.1};
GN   OrderedLocusNames=Jann_1674 {ECO:0000313|EMBL:ABD54591.1};
OS   Jannaschia sp. (strain CCS1).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Roseobacteraceae; Jannaschia.
OX   NCBI_TaxID=290400 {ECO:0000313|EMBL:ABD54591.1, ECO:0000313|Proteomes:UP000008326};
RN   [1] {ECO:0000313|Proteomes:UP000008326}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CCS1 {ECO:0000313|Proteomes:UP000008326};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Pitluck S., Brettin T., Bruce D.,
RA   Han C., Tapia R., Gilna P., Chertkov O., Saunders E., Schmutz J.,
RA   Larimer F., Land M., Kyrpides N., Lykidis A., Moran M.A., Belas R., Ye W.,
RA   Buchan A., Gonzalez J.M., Schell M.A., Richardson P.;
RT   "Complete sequence of chromosome of Jannaschia sp. CCS1.";
RL   Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ABD54591.1, ECO:0000313|Proteomes:UP000008326}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CCS1 {ECO:0000313|EMBL:ABD54591.1,
RC   ECO:0000313|Proteomes:UP000008326};
RX   PubMed=17526795; DOI=10.1128/AEM.02580-06;
RA   Moran M.A., Belas R., Schell M.A., Gonzalez J.M., Sun F., Sun S.,
RA   Binder B.J., Edmonds J., Ye W., Orcutt B., Howard E.C., Meile C.,
RA   Palefsky W., Goesmann A., Ren Q., Paulsen I., Ulrich L.E., Thompson L.S.,
RA   Saunders E., Buchan A.;
RT   "Ecological genomics of marine Roseobacters.";
RL   Appl. Environ. Microbiol. 73:4559-4569(2007).
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DR   EMBL; CP000264; ABD54591.1; -; Genomic_DNA.
DR   RefSeq; WP_011454796.1; NC_007802.1.
DR   AlphaFoldDB; Q28RS1; -.
DR   STRING; 290400.Jann_1674; -.
DR   KEGG; jan:Jann_1674; -.
DR   eggNOG; COG2114; Bacteria.
DR   eggNOG; COG4252; Bacteria.
DR   HOGENOM; CLU_000445_85_1_5; -.
DR   OrthoDB; 9789782at2; -.
DR   Proteomes; UP000008326; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd07302; CHD; 1.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR007890; CHASE2.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR   PANTHER; PTHR43081:SF1; PH-SENSITIVE ADENYLATE CYCLASE RV1264; 1.
DR   Pfam; PF05226; CHASE2; 1.
DR   Pfam; PF00211; Guanylate_cyc; 1.
DR   SMART; SM01080; CHASE2; 1.
DR   SMART; SM00044; CYCc; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008326};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        354..373
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        380..401
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        407..430
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          473..605
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
SQ   SEQUENCE   731 AA;  77319 MW;  890DBCF670A14104 CRC64;
     MARLTFALGL LVTVAMVVLT AFPPPILDRA RDAVFDGYQR SAPRAYDPDA PVHIIDIDEA
     ALETYGQWPW PRSYMAEMTD RLFDHGAAAV GFDVLFPEPD RTSPDLIVES WTRFADAPAP
     VLPDLGIAPH DSRFAQSMQG RAVVLSVAGG LEGTMPEAVA GFAVTGATPT TLTTYPGAIS
     NLEELTAAAS GIGTISLGRN ADGITRTVPM VSEFGGVLIP SLSAELLRVA QGAGGHILKT
     TEASGEVSGG TVAATAMQTG ALAFPLEADG RFRLYYAGYQ PERVTPAGEL FDADGIDPAL
     QQRLAGRIIL VGSSAQGLFD IRTTPLDGQI AGVTLHAEII EQIVTGSFLS RPDWMRGLEI
     LIVALTGLAL TILNRMERPL LGLSAALAFG GGSVVGGILA FTSLGMLFSP VMTVLTATLV
     YLPGTTLGYL AKERARRSIR ERFARFLPPP LIAEIEKNPA AALTPEGAER DLTVMFVDMR
     GFSTVTEGMP PDRVVTLVNT FLSAVAEALV DHGATIDKFM GDAVMAFWNA PIERDDHAVA
     ALGALHAIND AAEQANFLLT SQGLPRVTLG VGLNTGPASV GLMGSRDRLS YTCIGDSVTL
     AARLEGLTRI YGTRNCVGPN TVAQCPAHLQ AVTLDLIAVK GFARAVEVST VLPRATPGLE
     EFSAALALAR TIFVARDWDG AEAAMMQVAK IKVPTCNTGL LAQLYLDRIA AYKEIPPPEG
     WQGEFVALSK R
//