Q28RJ8 (URE2_JANSC) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Urease subunit beta
EC=3.5.1.5

Alternative name(s):
Urea amidohydrolase subunit beta

Gene names

Name:	ureB
Ordered Locus Names:	Jann_1747

Organism

Jannaschia sp. (strain CCS1) [Complete proteome] [HAMAP]

Taxonomic identifier

290400 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Jannaschia

Protein attributes

Sequence length	101 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Urea + H2O = CO2 + 2 NH3. HAMAP-Rule MF_01954
Pathway	Nitrogen metabolism; urea degradation; CO(2) and NH(3) from urea (urease route): step 1/1. HAMAP-Rule MF_01954
Subunit structure	Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the urease beta subunit family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	urea catabolic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	urease activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 101	101	Urease subunit beta HAMAP-Rule MF_01954		PRO_0000239894

Sequences

	Sequence		Length	Mass (Da)
	Q28RJ8 [UniParc]. Last modified April 4, 2006. Version 1. Checksum: 75BB37079FA56B52	FASTA	101	10,776
	10 20 30 40 50 60 MIPGEVMPAD GTIELNAGAQ AVTLEVSNTG DRPIQVGSHY HFGEANGALD FDRDAARGMR 70 80 90 100 LDIAAGTAVR FEPGQTREVR LVPYGGARRV FGFNQTVMGD L

References

[1]

"Complete sequence of chromosome of Jannaschia sp. CCS1." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Chertkov O., Saunders E., Schmutz J., Larimer F. , Land M., Kyrpides N., Lykidis A., Moran M.A., Belas R., Ye W., Buchan A., Gonzalez J.M., Schell M.A., Richardson P. Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CCS1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000264 Genomic DNA. Translation: ABD54664.1.
RefSeq	YP_509689.1. NC_007802.1.
3D structure databases
ProteinModelPortal	Q28RJ8.
SMR	Q28RJ8. Positions 1-101.
ModBase	Search...
Protein-protein interaction databases
STRING	290400.Jann_1747.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABD54664; ABD54664; Jann_1747.
GeneID	3934195.
KEGG	jan:Jann_1747.
PATRIC	22147218. VBIJanSp43325_1879.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0832.
HOGENOM	HOG000077770.
KO	K01429.
OMA	REVYGFQ.
Enzyme and pathway databases
BioCyc	JSP290400:GI1R-1800-MONOMER.
UniPathway	UPA00258; UER00370.
Family and domain databases
Gene3D	2.10.150.10. 1 hit.
HAMAP	MF_01954. Urease_beta.
InterPro	IPR002019. Urease_beta. [Graphical view]
Pfam	PF00699. Urease_beta. 1 hit. [Graphical view]
SUPFAM	SSF51278. Urease_beta. 1 hit.
TIGRFAMs	TIGR00192. urease_beta. 1 hit.
ProtoNet	Search...

Entry information

Entry name

URE2_JANSC

Accession

Primary (citable) accession number: Q28RJ8

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 13, 2006
Last sequence update:	April 4, 2006
Last modified:	May 1, 2013
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program