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Q28RJ8 (URE2_JANSC) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Urease subunit beta

EC=3.5.1.5
Alternative name(s):
Urea amidohydrolase subunit beta
Gene names
Name:ureB
Ordered Locus Names:Jann_1747
OrganismJannaschia sp. (strain CCS1) [Complete proteome] [HAMAP]
Taxonomic identifier290400 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeJannaschia

Protein attributes

Sequence length101 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Urea + H2O = CO2 + 2 NH3. HAMAP-Rule MF_01954

Pathway

Nitrogen metabolism; urea degradation; CO(2) and NH(3) from urea (urease route): step 1/1. HAMAP-Rule MF_01954

Subunit structure

Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme By similarity.

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_01954.

Sequence similarities

Belongs to the urease beta subunit family.

Ontologies

Keywords
   Cellular componentCytoplasm
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processurea catabolic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionurease activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 101101Urease subunit beta HAMAP-Rule MF_01954
PRO_0000239894

Sequences

Sequence LengthMass (Da)Tools
Q28RJ8 [UniParc].

Last modified April 4, 2006. Version 1.
Checksum: 75BB37079FA56B52

FASTA10110,776
        10         20         30         40         50         60 
MIPGEVMPAD GTIELNAGAQ AVTLEVSNTG DRPIQVGSHY HFGEANGALD FDRDAARGMR 

        70         80         90        100 
LDIAAGTAVR FEPGQTREVR LVPYGGARRV FGFNQTVMGD L 

« Hide

References

[1]"Complete sequence of chromosome of Jannaschia sp. CCS1."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Chertkov O., Saunders E., Schmutz J., Larimer F. expand/collapse author list , Land M., Kyrpides N., Lykidis A., Moran M.A., Belas R., Ye W., Buchan A., Gonzalez J.M., Schell M.A., Richardson P.
Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CCS1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000264 Genomic DNA. Translation: ABD54664.1.
RefSeqYP_509689.1. NC_007802.1.

3D structure databases

ProteinModelPortalQ28RJ8.
SMRQ28RJ8. Positions 1-101.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING290400.Jann_1747.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABD54664; ABD54664; Jann_1747.
GeneID3934195.
KEGGjan:Jann_1747.
PATRIC22147218. VBIJanSp43325_1879.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0832.
HOGENOMHOG000077770.
KOK01429.
OMAREVYGFQ.
OrthoDBEOG69PQ9G.

Enzyme and pathway databases

BioCycJSP290400:GI1R-1759-MONOMER.
UniPathwayUPA00258; UER00370.

Family and domain databases

Gene3D2.10.150.10. 1 hit.
HAMAPMF_01954. Urease_beta.
InterProIPR002019. Urease_beta.
[Graphical view]
PfamPF00699. Urease_beta. 1 hit.
[Graphical view]
SUPFAMSSF51278. SSF51278. 1 hit.
TIGRFAMsTIGR00192. urease_beta. 1 hit.
ProtoNetSearch...

Entry information

Entry nameURE2_JANSC
AccessionPrimary (citable) accession number: Q28RJ8
Entry history
Integrated into UniProtKB/Swiss-Prot: June 13, 2006
Last sequence update: April 4, 2006
Last modified: February 19, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways