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Q28RA9

- PUR5_JANSC

UniProt

Q28RA9 - PUR5_JANSC

Protein

Phosphoribosylformylglycinamidine cyclo-ligase

Gene

purM

Organism
Jannaschia sp. (strain CCS1)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 58 (01 Oct 2014)
      Sequence version 1 (04 Apr 2006)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. phosphoribosylformylglycinamidine cyclo-ligase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. 'de novo' IMP biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Ligase

    Keywords - Biological processi

    Purine biosynthesis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciJSP290400:GI1R-1851-MONOMER.
    UniPathwayiUPA00074; UER00129.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoribosylformylglycinamidine cyclo-ligaseUniRule annotation (EC:6.3.3.1UniRule annotation)
    Alternative name(s):
    AIR synthaseUniRule annotation
    AIRSUniRule annotation
    Phosphoribosyl-aminoimidazole synthetaseUniRule annotation
    Gene namesi
    Name:purMUniRule annotation
    Ordered Locus Names:Jann_1836
    OrganismiJannaschia sp. (strain CCS1)
    Taxonomic identifieri290400 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeJannaschia
    ProteomesiUP000008326: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 349349Phosphoribosylformylglycinamidine cyclo-ligasePRO_0000258362Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi290400.Jann_1836.

    Structurei

    3D structure databases

    ProteinModelPortaliQ28RA9.
    SMRiQ28RA9. Positions 8-346.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the AIR synthase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0150.
    HOGENOMiHOG000229090.
    KOiK01933.
    OMAiISAHEMH.
    OrthoDBiEOG61CM1V.

    Family and domain databases

    Gene3Di3.30.1330.10. 1 hit.
    3.90.650.10. 1 hit.
    HAMAPiMF_00741_B. AIRS_B.
    InterProiIPR010918. AIR_synth_C_dom.
    IPR000728. AIR_synth_N_dom.
    IPR004733. PurM_cligase.
    IPR016188. PurM_N-like.
    [Graphical view]
    PfamiPF00586. AIRS. 1 hit.
    PF02769. AIRS_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF55326. SSF55326. 1 hit.
    SSF56042. SSF56042. 1 hit.
    TIGRFAMsiTIGR00878. purM. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q28RA9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTDSKPDALT YADAGVDIDA GNALVDRIKP AAAATNRAGV MAGLGGFGAL    50
    FDLKAAGYDD PVLVAATDGV GTKLKIAIDT GNFDTIGVDL VAMCVNDLVC 100
    QGAEPLFFLD YFATGKLDVD DAARIVEGIA AGCKASGCAL IGGETAEMPG 150
    MYAPGDFDLA GFSVGAMERG RALPDGVAEG DVLLGLASDG VHSNGYSLVR 200
    RVVERSGLAW DAPAPFAQSS LGEALLAPTR LYVQPALAAI RAGGVHALAH 250
    ITGGGLTENI PRVLPDGLGV DIDLSSWSLP PVFGWLAQEG ALDQAELLKT 300
    FNAGLGMVLV VSADAVDGLT WTLEDAGESV HRIGTVTAGA GVRYSGSLG 349
    Length:349
    Mass (Da):35,418
    Last modified:April 4, 2006 - v1
    Checksum:i123016D0B626BB29
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000264 Genomic DNA. Translation: ABD54753.1.
    RefSeqiWP_011454958.1. NC_007802.1.
    YP_509778.1. NC_007802.1.

    Genome annotation databases

    EnsemblBacteriaiABD54753; ABD54753; Jann_1836.
    GeneIDi3934287.
    KEGGijan:Jann_1836.
    PATRICi22147404. VBIJanSp43325_1969.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000264 Genomic DNA. Translation: ABD54753.1 .
    RefSeqi WP_011454958.1. NC_007802.1.
    YP_509778.1. NC_007802.1.

    3D structure databases

    ProteinModelPortali Q28RA9.
    SMRi Q28RA9. Positions 8-346.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 290400.Jann_1836.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABD54753 ; ABD54753 ; Jann_1836 .
    GeneIDi 3934287.
    KEGGi jan:Jann_1836.
    PATRICi 22147404. VBIJanSp43325_1969.

    Phylogenomic databases

    eggNOGi COG0150.
    HOGENOMi HOG000229090.
    KOi K01933.
    OMAi ISAHEMH.
    OrthoDBi EOG61CM1V.

    Enzyme and pathway databases

    UniPathwayi UPA00074 ; UER00129 .
    BioCyci JSP290400:GI1R-1851-MONOMER.

    Family and domain databases

    Gene3Di 3.30.1330.10. 1 hit.
    3.90.650.10. 1 hit.
    HAMAPi MF_00741_B. AIRS_B.
    InterProi IPR010918. AIR_synth_C_dom.
    IPR000728. AIR_synth_N_dom.
    IPR004733. PurM_cligase.
    IPR016188. PurM_N-like.
    [Graphical view ]
    Pfami PF00586. AIRS. 1 hit.
    PF02769. AIRS_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF55326. SSF55326. 1 hit.
    SSF56042. SSF56042. 1 hit.
    TIGRFAMsi TIGR00878. purM. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: CCS1.

    Entry informationi

    Entry nameiPUR5_JANSC
    AccessioniPrimary (citable) accession number: Q28RA9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 31, 2006
    Last sequence update: April 4, 2006
    Last modified: October 1, 2014
    This is version 58 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3