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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Jannaschia sp. (strain CCS1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei341 – 3411Proton donorUniRule annotation
Active sitei372 – 3721UniRule annotation
Active sitei501 – 5011UniRule annotation

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciJSP290400:GI1R-1986-MONOMER.
UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:Jann_1971
OrganismiJannaschia sp. (strain CCS1)
Taxonomic identifieri290400 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeJannaschia
ProteomesiUP000008326 Componenti: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 537537Glucose-6-phosphate isomerasePRO_0000252625Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi290400.Jann_1971.

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261371.
KOiK01810.
OMAiFELANDC.
OrthoDBiEOG64R61J.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q28QX4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGEIWSELKA HHSAKSRRKM LDLFEKGNRV QAFSATVDGL YFDFSKTNLD
60 70 80 90 100
DGALSLLLEL ARVKGVESRR AAMFAGDKIN ETEGRAVLHT ALRAPAGPIK
110 120 130 140 150
VDGQDIMPGV LETRARCFTF AQQVRDGSFT AQGGRITDVV NIGIGGSDLG
160 170 180 190 200
PAMATLALAP YHDGPRLHYV SNVDGADMNG ALQGIDPKTT LVIVASKTFT
210 220 230 240 250
TIETMTNAQT ARDWMAQDVA DPSAQFVALS SSTEKAGAFG IPPERTFGFE
260 270 280 290 300
DWVGGRYSLW GPIGLGLMIA IGPEAFQQFL DGAATMDRHF QEADLADNLP
310 320 330 340 350
VLLALVGMWH NQVEGHATRA VLPYDNRLSR LPAYLQQLEM ESNGKSVAMD
360 370 380 390 400
GSALQQNSGP VVWGEPGTNG QHAFYQLIHQ GTRVVPCEFL VAAKGHEPDL
410 420 430 440 450
THHHRLLVAN CLAQSEALMR GRSMEEARAL MAAKGLEGAE LERQAAHRVF
460 470 480 490 500
PGNRPSTTLL YDQLTPFTLG QIIALYEHRV FVEGVILGIN SFDQWGVELG
510 520 530
KELATALEPV LTGKDDGAGK DGSTLALVDA VKAVGGI
Length:537
Mass (Da):57,868
Last modified:April 4, 2006 - v1
Checksum:i8D46DF039CE1FCE0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000264 Genomic DNA. Translation: ABD54888.1.
RefSeqiWP_011455093.1. NC_007802.1.
YP_509913.1. NC_007802.1.

Genome annotation databases

EnsemblBacteriaiABD54888; ABD54888; Jann_1971.
GeneIDi3934422.
KEGGijan:Jann_1971.
PATRICi22147692. VBIJanSp43325_2113.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000264 Genomic DNA. Translation: ABD54888.1.
RefSeqiWP_011455093.1. NC_007802.1.
YP_509913.1. NC_007802.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi290400.Jann_1971.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABD54888; ABD54888; Jann_1971.
GeneIDi3934422.
KEGGijan:Jann_1971.
PATRICi22147692. VBIJanSp43325_2113.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261371.
KOiK01810.
OMAiFELANDC.
OrthoDBiEOG64R61J.

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.
BioCyciJSP290400:GI1R-1986-MONOMER.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CCS1.

Entry informationi

Entry nameiG6PI_JANSC
AccessioniPrimary (citable) accession number: Q28QX4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 17, 2006
Last sequence update: April 4, 2006
Last modified: April 1, 2015
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.