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Protein

Exodeoxyribonuclease 7 large subunit

Gene

xseA

Organism
Jannaschia sp. (strain CCS1)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.UniRule annotationSAAS annotation

Catalytic activityi

Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates.UniRule annotationSAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionExonucleaseUniRule annotationSAAS annotation, Hydrolase, Nuclease

Names & Taxonomyi

Protein namesi
Recommended name:
Exodeoxyribonuclease 7 large subunitUniRule annotation (EC:3.1.11.6UniRule annotation)
Alternative name(s):
Exodeoxyribonuclease VII large subunitUniRule annotation
Short name:
Exonuclease VII large subunitUniRule annotation
Gene namesi
Name:xseAUniRule annotation
Ordered Locus Names:Jann_3300Imported
OrganismiJannaschia sp. (strain CCS1)Imported
Taxonomic identifieri290400 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeJannaschia
Proteomesi
  • UP000008326 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Heterooligomer composed of large and small subunits.UniRule annotation

Protein-protein interaction databases

STRINGi290400.Jann_3300.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini16 – 109tRNA_anti_2InterPro annotationAdd BLAST94
Domaini132 – 493Exonuc_VII_LInterPro annotationAdd BLAST362

Sequence similaritiesi

Belongs to the XseA family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105DVS. Bacteria.
COG1570. LUCA.
HOGENOMiHOG000229266.
KOiK03601.
OMAiNARRRWP.
OrthoDBiPOG091H02EK.

Family and domain databases

CDDicd04489. ExoVII_LU_OBF. 1 hit.
HAMAPiMF_00378. Exonuc_7_L. 1 hit.
InterProiView protein in InterPro
IPR003753. Exonuc_VII_L.
IPR020579. Exonuc_VII_lsu_C.
IPR025824. OB-fold_nuc-bd_dom.
PANTHERiPTHR30008. PTHR30008. 1 hit.
PfamiView protein in Pfam
PF02601. Exonuc_VII_L. 1 hit.
PF13742. tRNA_anti_2. 1 hit.
TIGRFAMsiTIGR00237. xseA. 1 hit.

Sequencei

Sequence statusi: Complete.

Q28M45-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDDLIDDEGT GNSPEFTVSE ISGAVKRTVE GAFAHVRVRG EVGRLSLPRS
60 70 80 90 100
GHIYLDLKDD RSVLASVVWK GVANRLTHRP EEGMEVIATG RLTTFPGQSK
110 120 130 140 150
YQLVIDDLQP AGAGALMAML EKRRKALAAE GLFDDARKQP LPFLPEVIGV
160 170 180 190 200
VTSPSGAVIR DILHRLRDRF PRKVLIWPVA VQGAKCGPDV ANAIRGFNAL
210 220 230 240 250
TPGGALPRPD LLIVARGGGS LEDLWGFNEE EVVRATADST IPLISAVGHE
260 270 280 290 300
TDTTLIDYAS DYRAPTPTGA AEKAVPVRMD MLNWLRQQEG ILTRAMTGAL
310 320 330 340 350
TMRAQRLADL SRALPRSDAL MEPARQRLDL AGLRLAPALA SRTKDARAQL
360 370 380 390 400
DRLAARLDPA LDRAVARKRL ALGERAAGLT PARLANVVRQ GRRDLDRLTV
410 420 430 440 450
RLDPQRLTAR TSKMEERLGQ ARARFAQAAN LSVRKRREAL DSLDRLRRTL
460 470 480 490 500
GYTETLGRGY AVIRAGEDVL TSKAAASAHA AMEIQFSDGR LGVTPTGATP
510
KAVKKAPKAK LPKDQGSLF
Length:519
Mass (Da):56,333
Last modified:April 4, 2006 - v1
Checksum:i4835B37C2F6EED1A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000264 Genomic DNA. Translation: ABD56217.1.
RefSeqiWP_011456419.1. NC_007802.1.

Genome annotation databases

EnsemblBacteriaiABD56217; ABD56217; Jann_3300.
KEGGijan:Jann_3300.

Similar proteinsi

Entry informationi

Entry nameiQ28M45_JANSC
AccessioniPrimary (citable) accession number: Q28M45
Entry historyiIntegrated into UniProtKB/TrEMBL: April 4, 2006
Last sequence update: April 4, 2006
Last modified: October 25, 2017
This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported