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Protein

tRNA pseudouridine synthase B

Gene

truB

Organism
Jannaschia sp. (strain CCS1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.UniRule annotation

Catalytic activityi

tRNA uridine(55) = tRNA pseudouridine(55).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei47NucleophileUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

tRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase BUniRule annotation (EC:5.4.99.25UniRule annotation)
Alternative name(s):
tRNA pseudouridine(55) synthaseUniRule annotation
Short name:
Psi55 synthaseUniRule annotation
tRNA pseudouridylate synthaseUniRule annotation
tRNA-uridine isomeraseUniRule annotation
Gene namesi
Name:truBUniRule annotation
Ordered Locus Names:Jann_4034
OrganismiJannaschia sp. (strain CCS1)
Taxonomic identifieri290400 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeJannaschia
Proteomesi
  • UP000008326 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000846071 – 301tRNA pseudouridine synthase BAdd BLAST301

Interactioni

Protein-protein interaction databases

STRINGi290400.Jann_4034.

Structurei

3D structure databases

ProteinModelPortaliQ28K11.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D0T. Bacteria.
COG0130. LUCA.
HOGENOMiHOG000231225.
KOiK03177.
OMAiYELQFIR.
OrthoDBiPOG091H02G9.

Family and domain databases

HAMAPiMF_01080. TruB_bact. 1 hit.
InterProiIPR020103. PsdUridine_synth_cat_dom.
IPR002501. PsdUridine_synth_N.
IPR014780. tRNA_psdUridine_synth_TruB.
IPR032819. TruB_C.
[Graphical view]
PANTHERiPTHR13767. PTHR13767. 1 hit.
PfamiPF16198. TruB_C_2. 1 hit.
PF01509. TruB_N. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
TIGRFAMsiTIGR00431. TruB. 1 hit.

Sequencei

Sequence statusi: Complete.

Q28K11-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARRNKGRDI SGWVLVDKPA GLTSTAVVNK VRWCFDAKKA GHAGTLDPDA
60 70 80 90 100
TGMLPVALGE ATKTIAYMSD DLKAYTFRVR LGVSTKTDDA EGEVLETSDT
110 120 130 140 150
RPTDTEIEAA LPAFVGDIQQ VPPQFSAVKV DGERAYDIAR GGGEMELAAR
160 170 180 190 200
DLYVESLSVI GRPDADHVDL EFVCGSGGYV RSIARDLGQV LGCFGHVLWL
210 220 230 240 250
RRTWVGAFDI EDAVGLDRVE ALARTDALYA LLQPVGLALH ALPELRVTDA
260 270 280 290 300
GAARLRNGNP GGVLPGNVEY GDLAWASLNG TPVAVGRYRS GELHPERVFN

L
Length:301
Mass (Da):32,274
Last modified:April 4, 2006 - v1
Checksum:i6B5A32BE0F705FE2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000264 Genomic DNA. Translation: ABD56951.1.
RefSeqiWP_011457147.1. NC_007802.1.

Genome annotation databases

EnsemblBacteriaiABD56951; ABD56951; Jann_4034.
KEGGijan:Jann_4034.
PATRICi22152026. VBIJanSp43325_4249.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000264 Genomic DNA. Translation: ABD56951.1.
RefSeqiWP_011457147.1. NC_007802.1.

3D structure databases

ProteinModelPortaliQ28K11.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi290400.Jann_4034.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABD56951; ABD56951; Jann_4034.
KEGGijan:Jann_4034.
PATRICi22152026. VBIJanSp43325_4249.

Phylogenomic databases

eggNOGiENOG4105D0T. Bacteria.
COG0130. LUCA.
HOGENOMiHOG000231225.
KOiK03177.
OMAiYELQFIR.
OrthoDBiPOG091H02G9.

Family and domain databases

HAMAPiMF_01080. TruB_bact. 1 hit.
InterProiIPR020103. PsdUridine_synth_cat_dom.
IPR002501. PsdUridine_synth_N.
IPR014780. tRNA_psdUridine_synth_TruB.
IPR032819. TruB_C.
[Graphical view]
PANTHERiPTHR13767. PTHR13767. 1 hit.
PfamiPF16198. TruB_C_2. 1 hit.
PF01509. TruB_N. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
TIGRFAMsiTIGR00431. TruB. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiTRUB_JANSC
AccessioniPrimary (citable) accession number: Q28K11
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: April 4, 2006
Last modified: November 2, 2016
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.