ID   PLD6_XENTR              Reviewed;         210 AA.
AC   Q28DT3;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   04-APR-2006, sequence version 1.
DT   16-JUN-2009, entry version 23.
DE   RecName: Full=Phospholipase D6;
DE            Short=PLD 6;
DE            EC=3.1.4.4;
DE   AltName: Full=Choline phosphatase 6;
DE   AltName: Full=Phosphatidylcholine-hydrolyzing phospholipase D6;
GN   Name=pld6; ORFNames=TGas067k05.1;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae;
OC   Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Gastrula;
RG   Sanger Xenopus tropicalis EST/cDNA project;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: A phosphatidylcholine + H(2)O = choline + a
CC       phosphatidate.
CC   -!- SUBCELLULAR LOCATION: Membrane; Single-pass membrane protein
CC       (Potential).
CC   -!- SIMILARITY: Belongs to the Phospholipase D family.
CC   -!- SIMILARITY: Contains 1 PLD phosphodiesterase domain.
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DR   EMBL; CR848611; CAJ83564.1; -; mRNA.
DR   RefSeq; NP_001016875.1; -.
DR   UniGene; Str.27332; -.
DR   GeneID; 549629; -.
DR   KEGG; xtr:549629; -.
DR   Xenbase; XB-FEAT-5729936; pld6.
DR   HOVERGEN; Q28DT3; -.
DR   OMA; Q28DT3; FPSQVTC.
DR   BRENDA; 3.1.4.4; 279072.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0070290; F:NAPE-specific phospholipase D activity; IEA:EC.
DR   GO; GO:0004630; F:phospholipase D activity; IEA:EC.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   InterPro; IPR001736; PLipase_D/transphosphatidylase.
DR   SMART; SM00155; PLDc; 1.
DR   PROSITE; PS50035; PLD; 1.
PE   2: Evidence at transcript level;
KW   Hydrolase; Lipid degradation; Membrane; Transmembrane.
FT   CHAIN         1    210       Phospholipase D6.
FT                                /FTId=PRO_0000325914.
FT   TRANSMEM      7     24       Potential.
FT   DOMAIN      138    165       PLD phosphodiesterase.
FT   ACT_SITE    143    143       Potential.
FT   ACT_SITE    145    145       Potential.
FT   ACT_SITE    150    150       Potential.
SQ   SEQUENCE   210 AA;  23883 MW;  1FA19F73A80D7063 CRC64;
     MLLWGRWKVA AGLAGLALSL ELLLRYMRRR KPIREVLFFP APVTCIEPVL YPMKQCSCPL
     PHTDSAFSRL LLLLLRAQRS LELCVFTFSC PSLARAVLLL HTRGVRVRVI TDNDYMAASG
     SQIGPLRSAG VAVRHDQSSG YMHHKFAVVD GTVVLTGSLN WTVQATQTNR ENILITDDRV
     IVKAYQQEFE RLWQEYDPAS YDFFPEKENK
//