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Protein

Protein phosphatase 1H

Gene

ppm1h

Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Names & Taxonomyi

Protein namesi
Recommended name:
Protein phosphatase 1H (EC:3.1.3.16)
Gene namesi
Name:ppm1h
ORF Names:TEgg016i20.1
OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Taxonomic identifieri8364 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana
ProteomesiUP000008143 Componenti: Unassembled WGS sequence

Organism-specific databases

XenbaseiXB-GENE-5872503. ppm1h.

Subcellular locationi

  • Nucleus By similarity
  • Cytoplasm By similarity

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 510510Protein phosphatase 1HPRO_0000286607Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ28DF4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini73 – 503431PPM-type phosphatasePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the PP2C family.Curated
Contains 1 PPM-type phosphatase domain.PROSITE-ProRule annotation

Phylogenomic databases

HOVERGENiHBG105802.
InParanoidiQ28DF4.
KOiK17503.

Family and domain databases

Gene3Di3.60.40.10. 4 hits.
InterProiIPR015655. PP2C.
IPR001932. PPM-type_phosphatase_dom.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiPF00481. PP2C. 2 hits.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 4 hits.
PROSITEiPS51746. PPM_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q28DF4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFTRVKSAVV SFMGGIMAGS SGLEHVNGSD LPVRFSYTRP EFLGLSPDEI
60 70 80 90 100
ECSADHIARP ILILKETQRL PWSTGYAEVI NAGKSTHNED QASCEVVFVK
110 120 130 140 150
KKSGVQSTPN KNSSSKRRSS LPNAEGLQLK DNQEVDGITF HYWALFDGHA
160 170 180 190 200
GAGAAVVASK LLHHHIAEQI PDIIDILKNS AVLPPTCLGE EPESTSSNSR
210 220 230 240 250
TLTRAASLRG GSGAPGSPST PPTRFFTEKK IPHECLVIGA LENAFKEMDL
260 270 280 290 300
RIERERSTYS ISGGCTALIV VYLLGKLYVA NAGDSRAIII RNGEIIPMSS
310 320 330 340 350
EFTPETERQR LQYLAFLQPH LLGNEFTHLE FPRRVQRKEV GKMMLYRDFN
360 370 380 390 400
MTGWAYKTIE ENDLKFPLIY GEGKKARVMA TIGVTRGLGD HDLKVHDSNI
410 420 430 440 450
YIKPFLSSVP EVRVYDLVQH EHSADDVLVL ATDGLWDVLF NEEVLEAVTS
460 470 480 490 500
FLANCDPDDP HRYTLAAQDL VMRARGVLKD RGWRISNDRL GSGDDISVYV
510
IPLEHGNRVS
Length:510
Mass (Da):56,461
Last modified:April 4, 2006 - v1
Checksum:i1FA4AB5EF752A5A0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR855546 mRNA. Translation: CAJ82033.1.
RefSeqiNP_001017305.1. NM_001017305.2.
UniGeneiStr.27509.

Genome annotation databases

GeneIDi550059.
KEGGixtr:550059.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR855546 mRNA. Translation: CAJ82033.1.
RefSeqiNP_001017305.1. NM_001017305.2.
UniGeneiStr.27509.

3D structure databases

ProteinModelPortaliQ28DF4.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi550059.
KEGGixtr:550059.

Organism-specific databases

CTDi57460.
XenbaseiXB-GENE-5872503. ppm1h.

Phylogenomic databases

HOVERGENiHBG105802.
InParanoidiQ28DF4.
KOiK17503.

Family and domain databases

Gene3Di3.60.40.10. 4 hits.
InterProiIPR015655. PP2C.
IPR001932. PPM-type_phosphatase_dom.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiPF00481. PP2C. 2 hits.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 4 hits.
PROSITEiPS51746. PPM_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Sanger Xenopus tropicalis EST/cDNA project
    Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Egg.

Entry informationi

Entry nameiPPM1H_XENTR
AccessioniPrimary (citable) accession number: Q28DF4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: April 4, 2006
Last modified: July 22, 2015
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.