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Protein
Submitted name:

E-selectin

Gene
N/A
Organism
Sus scrofa (Pig)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandLectinImported

Names & Taxonomyi

Protein namesi
Submitted name:
E-selectinImported
OrganismiSus scrofa (Pig)Imported
Taxonomic identifieri9823 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaSuinaSuidaeSus

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei430 – 452HelicalSequence analysisAdd BLAST23

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_500420390023 – 482Sequence analysisAdd BLAST460

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi166 ↔ 175PROSITE-ProRule annotation
Disulfide bondi208 ↔ 235PROSITE-ProRule annotation
Disulfide bondi271 ↔ 298PROSITE-ProRule annotation
Disulfide bondi334 ↔ 361PROSITE-ProRule annotation
Disulfide bondi393 ↔ 420PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationSAAS annotation

Proteomic databases

PaxDbiQ28982.

Interactioni

Protein-protein interaction databases

STRINGi9823.ENSSSCP00000006699.

Structurei

3D structure databases

ProteinModelPortaliQ28982.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini20 – 140C-type lectinInterPro annotationAdd BLAST121
Domaini140 – 176EGF-likeInterPro annotationAdd BLAST37
Domaini179 – 237Sushi (CCP/SCR)InterPro annotationAdd BLAST59
Domaini251 – 300Sushi (CCP/SCR)InterPro annotationAdd BLAST50
Domaini301 – 363Sushi (CCP/SCR)InterPro annotationAdd BLAST63
Domaini364 – 422Sushi (CCP/SCR)InterPro annotationAdd BLAST59

Keywords - Domaini

EGF-like domainPROSITE-ProRule annotationSAAS annotation, RepeatSAAS annotation, SignalSequence analysis, SushiPROSITE-ProRule annotation, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG4297. Eukaryota.
ENOG410XPJ1. LUCA.
HOGENOMiHOG000236254.
HOVERGENiHBG052375.

Family and domain databases

CDDicd00033. CCP. 4 hits.
cd03592. CLECT_selectins_like. 1 hit.
Gene3Di3.10.100.10. 1 hit.
InterProiView protein in InterPro
IPR001304. C-type_lectin-like.
IPR016186. C-type_lectin-like/link.
IPR018378. C-type_lectin_CS.
IPR016187. CTDL_fold.
IPR013032. EGF-like_CS.
IPR000742. EGF-like_dom.
IPR033991. Selectin_CTLD.
IPR002396. Selectin_superfamily.
IPR000436. Sushi_SCR_CCP_dom.
PfamiView protein in Pfam
PF00059. Lectin_C. 1 hit.
PF00084. Sushi. 4 hits.
PRINTSiPR00343. SELECTIN.
SMARTiView protein in SMART
SM00032. CCP. 4 hits.
SM00034. CLECT. 1 hit.
SUPFAMiSSF56436. SSF56436. 1 hit.
SSF57535. SSF57535. 4 hits.
PROSITEiView protein in PROSITE
PS00615. C_TYPE_LECTIN_1. 1 hit.
PS50041. C_TYPE_LECTIN_2. 1 hit.
PS00022. EGF_1. 1 hit.
PS01186. EGF_2. 1 hit.
PS50026. EGF_3. 1 hit.
PS50923. SUSHI. 4 hits.

Sequencei

Sequence statusi: Complete.

Q28982-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIASQFLSAL PLVLLLLRES GAWSYSASTE TMTFDDASAY CQQRYTHLVA
60 70 80 90 100
IQNHAEIEYL NSTFNYSASY YWIGIRKING TWTWIGTKKA LTPEATNWAP
110 120 130 140 150
GEPNNKQSNE DCVEIYIKRD KDSGKWNDER CSKKKLALCY TAACTPTSCS
160 170 180 190 200
GHGECIETIN SSTCQCYPGF RGLQCEQVVE CDALENPVNG VVTCPQSLPW
210 220 230 240 250
NTTCAFECKE GFELIGPEHL QCTSSGSWDG KKPTCKAVTC DTVGHPQNGD
260 270 280 290 300
VSCNHSSIGE FAYKSTCHFT CAEGFGLQGP AQIECTAQGQ WTQQAPVCKA
310 320 330 340 350
VKCPAVSQPK NGLVKFTHSP TGEFTYKSSC AFSCEEGFEL RGSAQLACTS
360 370 380 390 400
QGQWTQEVPS CQVVQCSSLE VPREINMSCS GEPVFGAVCT FACPEGWMLN
410 420 430 440 450
GSVALTCGAT GHWSGMLPTC EAPAESKIPL AMGLAAGGVS FMTSASFLLW
460 470 480
LLKRLRKRAK NLFLPAAPNA FNPMDPTKCL LT
Length:482
Mass (Da):52,341
Last modified:November 1, 1996 - v1
Checksum:i97DC5D70BF115944
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U37521 Genomic DNA. Translation: AAC48680.1.
PIRiJC5092.
UniGeneiSsc.16297.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U37521 Genomic DNA. Translation: AAC48680.1.
PIRiJC5092.
UniGeneiSsc.16297.

3D structure databases

ProteinModelPortaliQ28982.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9823.ENSSSCP00000006699.

Proteomic databases

PaxDbiQ28982.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG4297. Eukaryota.
ENOG410XPJ1. LUCA.
HOGENOMiHOG000236254.
HOVERGENiHBG052375.

Family and domain databases

CDDicd00033. CCP. 4 hits.
cd03592. CLECT_selectins_like. 1 hit.
Gene3Di3.10.100.10. 1 hit.
InterProiView protein in InterPro
IPR001304. C-type_lectin-like.
IPR016186. C-type_lectin-like/link.
IPR018378. C-type_lectin_CS.
IPR016187. CTDL_fold.
IPR013032. EGF-like_CS.
IPR000742. EGF-like_dom.
IPR033991. Selectin_CTLD.
IPR002396. Selectin_superfamily.
IPR000436. Sushi_SCR_CCP_dom.
PfamiView protein in Pfam
PF00059. Lectin_C. 1 hit.
PF00084. Sushi. 4 hits.
PRINTSiPR00343. SELECTIN.
SMARTiView protein in SMART
SM00032. CCP. 4 hits.
SM00034. CLECT. 1 hit.
SUPFAMiSSF56436. SSF56436. 1 hit.
SSF57535. SSF57535. 4 hits.
PROSITEiView protein in PROSITE
PS00615. C_TYPE_LECTIN_1. 1 hit.
PS50041. C_TYPE_LECTIN_2. 1 hit.
PS00022. EGF_1. 1 hit.
PS01186. EGF_2. 1 hit.
PS50026. EGF_3. 1 hit.
PS50923. SUSHI. 4 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiQ28982_PIG
AccessioniPrimary (citable) accession number: Q28982
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: April 12, 2017
This is version 108 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.