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Protein
Submitted name:

E-selectin

Gene
N/A
Organism
Sus scrofa (Pig)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

LectinImported

Names & Taxonomyi

Protein namesi
Submitted name:
E-selectinImported
OrganismiSus scrofa (Pig)Imported
Taxonomic identifieri9823 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaSuinaSuidaeSus

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei430 – 45223HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2222Sequence analysisAdd
BLAST
Chaini23 – 482460Sequence analysisPRO_5004203900Add
BLAST

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

PaxDbiQ28982.

Interactioni

Protein-protein interaction databases

STRINGi9823.ENSSSCP00000006699.

Structurei

3D structure databases

ProteinModelPortaliQ28982.
SMRiQ28982. Positions 23-179.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini20 – 140121C-type lectinInterPro annotationAdd
BLAST
Domaini140 – 17637EGF-likeInterPro annotationAdd
BLAST
Domaini179 – 23759Sushi (CCP/SCR)InterPro annotationAdd
BLAST
Domaini251 – 30050Sushi (CCP/SCR)InterPro annotationAdd
BLAST
Domaini301 – 36363Sushi (CCP/SCR)InterPro annotationAdd
BLAST
Domaini364 – 42259Sushi (CCP/SCR)InterPro annotationAdd
BLAST

Sequence similaritiesi

Contains C-type lectin domain.SAAS annotation

Keywords - Domaini

EGF-like domainSAAS annotation, RepeatSAAS annotation, SignalSequence analysis, SushiSAAS annotation, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG4297. Eukaryota.
ENOG410XPJ1. LUCA.
HOGENOMiHOG000236254.
HOVERGENiHBG052375.

Family and domain databases

Gene3Di3.10.100.10. 1 hit.
InterProiIPR001304. C-type_lectin.
IPR016186. C-type_lectin-like.
IPR018378. C-type_lectin_CS.
IPR016187. C-type_lectin_fold.
IPR013032. EGF-like_CS.
IPR000742. EGF-like_dom.
IPR002396. Selectin_superfamily.
IPR000436. Sushi_SCR_CCP_dom.
[Graphical view]
PfamiPF00059. Lectin_C. 1 hit.
PF00084. Sushi. 4 hits.
[Graphical view]
PRINTSiPR00343. SELECTIN.
SMARTiSM00032. CCP. 4 hits.
SM00034. CLECT. 1 hit.
[Graphical view]
SUPFAMiSSF56436. SSF56436. 1 hit.
SSF57535. SSF57535. 4 hits.
PROSITEiPS00615. C_TYPE_LECTIN_1. 1 hit.
PS50041. C_TYPE_LECTIN_2. 1 hit.
PS00022. EGF_1. 1 hit.
PS01186. EGF_2. 1 hit.
PS50026. EGF_3. 1 hit.
PS50923. SUSHI. 4 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q28982-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIASQFLSAL PLVLLLLRES GAWSYSASTE TMTFDDASAY CQQRYTHLVA
60 70 80 90 100
IQNHAEIEYL NSTFNYSASY YWIGIRKING TWTWIGTKKA LTPEATNWAP
110 120 130 140 150
GEPNNKQSNE DCVEIYIKRD KDSGKWNDER CSKKKLALCY TAACTPTSCS
160 170 180 190 200
GHGECIETIN SSTCQCYPGF RGLQCEQVVE CDALENPVNG VVTCPQSLPW
210 220 230 240 250
NTTCAFECKE GFELIGPEHL QCTSSGSWDG KKPTCKAVTC DTVGHPQNGD
260 270 280 290 300
VSCNHSSIGE FAYKSTCHFT CAEGFGLQGP AQIECTAQGQ WTQQAPVCKA
310 320 330 340 350
VKCPAVSQPK NGLVKFTHSP TGEFTYKSSC AFSCEEGFEL RGSAQLACTS
360 370 380 390 400
QGQWTQEVPS CQVVQCSSLE VPREINMSCS GEPVFGAVCT FACPEGWMLN
410 420 430 440 450
GSVALTCGAT GHWSGMLPTC EAPAESKIPL AMGLAAGGVS FMTSASFLLW
460 470 480
LLKRLRKRAK NLFLPAAPNA FNPMDPTKCL LT
Length:482
Mass (Da):52,341
Last modified:November 1, 1996 - v1
Checksum:i97DC5D70BF115944
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U37521 Genomic DNA. Translation: AAC48680.1.
PIRiJC5092.
UniGeneiSsc.16297.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U37521 Genomic DNA. Translation: AAC48680.1.
PIRiJC5092.
UniGeneiSsc.16297.

3D structure databases

ProteinModelPortaliQ28982.
SMRiQ28982. Positions 23-179.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9823.ENSSSCP00000006699.

Proteomic databases

PaxDbiQ28982.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG4297. Eukaryota.
ENOG410XPJ1. LUCA.
HOGENOMiHOG000236254.
HOVERGENiHBG052375.

Family and domain databases

Gene3Di3.10.100.10. 1 hit.
InterProiIPR001304. C-type_lectin.
IPR016186. C-type_lectin-like.
IPR018378. C-type_lectin_CS.
IPR016187. C-type_lectin_fold.
IPR013032. EGF-like_CS.
IPR000742. EGF-like_dom.
IPR002396. Selectin_superfamily.
IPR000436. Sushi_SCR_CCP_dom.
[Graphical view]
PfamiPF00059. Lectin_C. 1 hit.
PF00084. Sushi. 4 hits.
[Graphical view]
PRINTSiPR00343. SELECTIN.
SMARTiSM00032. CCP. 4 hits.
SM00034. CLECT. 1 hit.
[Graphical view]
SUPFAMiSSF56436. SSF56436. 1 hit.
SSF57535. SSF57535. 4 hits.
PROSITEiPS00615. C_TYPE_LECTIN_1. 1 hit.
PS50041. C_TYPE_LECTIN_2. 1 hit.
PS00022. EGF_1. 1 hit.
PS01186. EGF_2. 1 hit.
PS50026. EGF_3. 1 hit.
PS50923. SUSHI. 4 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The intron-exon structure of the porcine E-selectin-encoding gene."
    Winkler H., Brostjan C., Csizmadia V., Natarajan G., Anrather J., Bach F.H.
    Gene 176:67-72(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ28982_PIG
AccessioniPrimary (citable) accession number: Q28982
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: May 11, 2016
This is version 102 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.