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Q28959

- Q28959_PIG

UniProt

Q28959 - Q28959_PIG

Protein
Submitted name:

Prohormone convertase

Gene

PC1/3

Organism
Sus scrofa (Pig)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 85 (01 Oct 2014)
      Sequence version 1 (01 Nov 1996)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. serine-type endopeptidase activity Source: InterPro

    Keywords - Molecular functioni

    Hydrolase, Protease, Serine proteaseUniRule annotationSAAS annotation

    Protein family/group databases

    MEROPSiS08.072.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Prohormone convertaseImported
    Gene namesi
    Name:PC1/3Imported
    OrganismiSus scrofa (Pig)Imported
    Taxonomic identifieri9823 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaSuinaSuidaeSus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2727 PotentialImportedAdd
    BLAST
    Chaini28 – 753726prohormone convertaseImportedPRO_5000144515Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi9823.ENSSSCP00000015068.

    Structurei

    3D structure databases

    ProteinModelPortaliQ28959.
    SMRiQ28959. Positions 31-103, 122-597.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the peptidase S8 family.UniRule annotation

    Keywords - Domaini

    SignalImported

    Phylogenomic databases

    eggNOGiCOG1404.
    HOGENOMiHOG000192536.
    HOVERGENiHBG008705.
    KOiK01359.

    Family and domain databases

    Gene3Di2.60.120.260. 1 hit.
    3.40.50.200. 1 hit.
    InterProiIPR008979. Galactose-bd-like.
    IPR000209. Peptidase_S8/S53_dom.
    IPR023827. Peptidase_S8_Asp-AS.
    IPR022398. Peptidase_S8_His-AS.
    IPR023828. Peptidase_S8_Ser-AS.
    IPR015500. Peptidase_S8_subtilisin-rel.
    IPR022005. Proho_convert.
    IPR009020. Prot_inh_propept.
    IPR002884. PrprotnconvertsP.
    [Graphical view]
    PANTHERiPTHR10795. PTHR10795. 1 hit.
    PfamiPF01483. P_proprotein. 1 hit.
    PF00082. Peptidase_S8. 1 hit.
    PF12177. Proho_convert. 1 hit.
    [Graphical view]
    PRINTSiPR00723. SUBTILISIN.
    SUPFAMiSSF49785. SSF49785. 1 hit.
    SSF52743. SSF52743. 1 hit.
    SSF54897. SSF54897. 1 hit.
    PROSITEiPS00136. SUBTILASE_ASP. 1 hit.
    PS00137. SUBTILASE_HIS. 1 hit.
    PS00138. SUBTILASE_SER. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q28959-1 [UniParc]FASTAAdd to Basket

    « Hide

    MERRAWTLQC TAFTLFCAWC ALNSVKAKRQ FVNEWAAEIP GGPEAASAIA    50
    EELGYDLLGQ IGSLENHYLF KHKSHPRRSR RSALHITKRL SDDDRVIWAE 100
    QQYEKERSKR SLLRDSALNL FNDPMWNQQW YLQDTRMTAA LPKLDLHVIP 150
    VWQKGITGKG VVITVLDDGL EWNHTDIYAN YDPEASYDFN DNDHDPFPRY 200
    DPTNENKHGT RCAGEIAMQA NNHKCGVGVA YNSKVGGIRM LDGIVTDAIE 250
    ASSIGFNPGH VDIYSASWGP NDDGKTVEGP GRLAQKAFEY GVKQGRQGKG 300
    SIFVWASGNG GRQGDNCDCD GYTDSIYTIS ISSASQQGLS PWYAEKCSST 350
    LATSYSSGDY TDQRITSADL HDDCTETHTG TSASAPLAAG IFALALEANP 400
    NLTWRDMQHL VVWTSEYDPL ANNPGWKKNG AGLMVNSRFG FGLLNAKALV 450
    DLADPRTWSS VPEKKECVVK DNDFEPRALK ANGEVIIEIP TRACEPQENA 500
    IKSLEHVQFE ATIEYSRRGD LHVTLTSAAG TGTVLLAERE RDTSPNGFKN 550
    WDFMSVHTWG ENPIGTWTLR ITDMSGRMQN EGRIVNWKLI LHGTSSQPEH 600
    MKQPRVYTSY NTVQNDRRGV EKVVDSEEEQ PTQENLNESP LVSKSPSGSS 650
    VGGRREELAE GAPSEAMLRL LQSAFSKNSA PKQSPKKSAS VKLNIPYENF 700
    YEALEKLNQP SQLKDSEDSL YNDYVDVFYN TKPYKHRDDR LLQALVDILR 750
    EEN 753
    Length:753
    Mass (Da):84,083
    Last modified:November 1, 1996 - v1
    Checksum:i6F06D3F16AB16BE3
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U20545 mRNA. Translation: AAA85577.1.
    PIRiS59959.
    RefSeqiNP_999203.1. NM_214038.1.
    UniGeneiSsc.92884.

    Genome annotation databases

    GeneIDi397103.
    KEGGissc:397103.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U20545 mRNA. Translation: AAA85577.1 .
    PIRi S59959.
    RefSeqi NP_999203.1. NM_214038.1.
    UniGenei Ssc.92884.

    3D structure databases

    ProteinModelPortali Q28959.
    SMRi Q28959. Positions 31-103, 122-597.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 9823.ENSSSCP00000015068.

    Protein family/group databases

    MEROPSi S08.072.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 397103.
    KEGGi ssc:397103.

    Organism-specific databases

    CTDi 5122.

    Phylogenomic databases

    eggNOGi COG1404.
    HOGENOMi HOG000192536.
    HOVERGENi HBG008705.
    KOi K01359.

    Family and domain databases

    Gene3Di 2.60.120.260. 1 hit.
    3.40.50.200. 1 hit.
    InterProi IPR008979. Galactose-bd-like.
    IPR000209. Peptidase_S8/S53_dom.
    IPR023827. Peptidase_S8_Asp-AS.
    IPR022398. Peptidase_S8_His-AS.
    IPR023828. Peptidase_S8_Ser-AS.
    IPR015500. Peptidase_S8_subtilisin-rel.
    IPR022005. Proho_convert.
    IPR009020. Prot_inh_propept.
    IPR002884. PrprotnconvertsP.
    [Graphical view ]
    PANTHERi PTHR10795. PTHR10795. 1 hit.
    Pfami PF01483. P_proprotein. 1 hit.
    PF00082. Peptidase_S8. 1 hit.
    PF12177. Proho_convert. 1 hit.
    [Graphical view ]
    PRINTSi PR00723. SUBTILISIN.
    SUPFAMi SSF49785. SSF49785. 1 hit.
    SSF52743. SSF52743. 1 hit.
    SSF54897. SSF54897. 1 hit.
    PROSITEi PS00136. SUBTILASE_ASP. 1 hit.
    PS00137. SUBTILASE_HIS. 1 hit.
    PS00138. SUBTILASE_SER. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Characterization of multiple prohormone convertase PC1/3 transcripts in porcine ovary."
      Dai G., Smeekens S.P., Steiner D.F., McMurtry J.P., Kwok S.C.
      Biochim. Biophys. Acta 1264:1-6(1995) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: OvaryImported.
    2. Kwok S.C.M.
      Submitted (FEB-1995) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: OvaryImported.

    Entry informationi

    Entry nameiQ28959_PIG
    AccessioniPrimary (citable) accession number: Q28959
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 1, 1996
    Last sequence update: November 1, 1996
    Last modified: October 1, 2014
    This is version 85 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)