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Protein
Submitted name:

17beta-estradiol dehydrogenase

Gene
N/A
Organism
Sus scrofa (Pig)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • 17-beta-hydroxysteroid dehydrogenase (NAD+) activity Source: UniProtKB

GO - Biological processi

  • androgen metabolic process Source: UniProtKB
  • estrogen metabolic process Source: UniProtKB
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
17beta-estradiol dehydrogenaseImported
OrganismiSus scrofa (Pig)Imported
Taxonomic identifieri9823 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaSuinaSuidaeSus

PTM / Processingi

Proteomic databases

PaxDbiQ28956.

Expressioni

Gene expression databases

GenevisibleiQ28956. SS.

Interactioni

Protein-protein interaction databases

STRINGi9823.ENSSSCP00000022446.

Structurei

3D structure databases

ProteinModelPortaliQ28956.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini485 – 601MaoC-likeInterPro annotationAdd BLAST117
Domaini629 – 732SCP2InterPro annotationAdd BLAST104

Phylogenomic databases

eggNOGiKOG1206. Eukaryota.
COG2030. LUCA.
HOVERGENiHBG002174.
KOiK12405.

Family and domain databases

Gene3Di3.10.129.10. 2 hits.
3.30.1050.10. 1 hit.
3.40.50.720. 1 hit.
InterProiIPR029069. HotDog_dom.
IPR002539. MaoC_dom.
IPR016040. NAD(P)-bd_dom.
IPR020904. Sc_DH/Rdtase_CS.
IPR003033. SCP2_sterol-bd_dom.
IPR002347. SDR_fam.
[Graphical view]
PfamiPF00106. adh_short. 1 hit.
PF01575. MaoC_dehydratas. 1 hit.
PF02036. SCP2. 1 hit.
[Graphical view]
PRINTSiPR00081. GDHRDH.
PR00080. SDRFAMILY.
SUPFAMiSSF51735. SSF51735. 1 hit.
SSF54637. SSF54637. 2 hits.
SSF55718. SSF55718. 1 hit.
PROSITEiPS00061. ADH_SHORT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q28956-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASMLNFYGR VVLVTGAGGG LGRTYALAFA ERGASVVVND LGGDMKGVGK
60 70 80 90 100
GSLAADKVVE EIRRKGGKAV ANYDSVEAGE KIVKAALDAF GRIDVVVNNA
110 120 130 140 150
GILRDRSFSR ISDEDWDMIQ RVHLRGSFMV TRAAWDHMKK QNFGRIIMTS
160 170 180 190 200
SAAGIYGNFG QANYSAAKLG LLGLSNSLAV EGKKNNIHCN TVAPVAGSRM
210 220 230 240 250
TQGFLPEDLI EALKPEYVAP LVLWLCHESC EENGSVFEVG AGWIGKLRWE
260 270 280 290 300
RTLGALVRQK NQPMTPEAVK ANWTKICDFD NATKPQRIQD SVSTVIEALS
310 320 330 340 350
KIDSSDGGIS ANNLSHATSA APSGLVEAVG YKFPPFSSSY TEVDTIMYAF
360 370 380 390 400
GVGASIKEPK DLKFIYEGNS DFSCLPTFGV ILAQKSLGGG GLAEIPGLSV
410 420 430 440 450
NFTKVLHGEH YLELYKPLPN AGDLKCEAVV ADVLDKRSGL VILIDVYSYS
460 470 480 490 500
GKELICYNQF SVFVMGSGGF GGKRTSDKDK VAVAIPNRPP DAILTDTTSL
510 520 530 540 550
NQAALYRLSG DWNPLHIDPD FASLAGFDRP ILHGLCTFGF SARHVLQQYA
560 570 580 590 600
DRDVLRFKAI KVRFAKPVYP GQTLQTEMWK EGNRIHFQTK VQETGDTVIS
610 620 630 640 650
NAYVDLVPTS DTLAKIPSEG GDLQSNLVFE EIGRRLQDIG QEMVKKVNAV
660 670 680 690 700
FEWHITKGEK IAAKWTIDLK NGAGKVYQGP AKGSADATFI LSDEVFMEVV
710 720 730
LGKLDPQKAF FSGRLKARGN IMLSQKLQMI LKDYAKI
Length:737
Mass (Da):80,102
Last modified:November 1, 1996 - v1
Checksum:i53D833567CC74FD9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X78201 mRNA. Translation: CAA55037.1.
RefSeqiNP_999471.1. NM_214306.1.
UniGeneiSsc.1199.

Genome annotation databases

GeneIDi397574.
KEGGissc:397574.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X78201 mRNA. Translation: CAA55037.1.
RefSeqiNP_999471.1. NM_214306.1.
UniGeneiSsc.1199.

3D structure databases

ProteinModelPortaliQ28956.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9823.ENSSSCP00000022446.

Proteomic databases

PaxDbiQ28956.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi397574.
KEGGissc:397574.

Organism-specific databases

CTDi3295.

Phylogenomic databases

eggNOGiKOG1206. Eukaryota.
COG2030. LUCA.
HOVERGENiHBG002174.
KOiK12405.

Gene expression databases

GenevisibleiQ28956. SS.

Family and domain databases

Gene3Di3.10.129.10. 2 hits.
3.30.1050.10. 1 hit.
3.40.50.720. 1 hit.
InterProiIPR029069. HotDog_dom.
IPR002539. MaoC_dom.
IPR016040. NAD(P)-bd_dom.
IPR020904. Sc_DH/Rdtase_CS.
IPR003033. SCP2_sterol-bd_dom.
IPR002347. SDR_fam.
[Graphical view]
PfamiPF00106. adh_short. 1 hit.
PF01575. MaoC_dehydratas. 1 hit.
PF02036. SCP2. 1 hit.
[Graphical view]
PRINTSiPR00081. GDHRDH.
PR00080. SDRFAMILY.
SUPFAMiSSF51735. SSF51735. 1 hit.
SSF54637. SSF54637. 2 hits.
SSF55718. SSF55718. 1 hit.
PROSITEiPS00061. ADH_SHORT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ28956_PIG
AccessioniPrimary (citable) accession number: Q28956
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: October 5, 2016
This is version 96 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.