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Protein
Submitted name:

Vascular cell adhesion molecule

Gene
N/A
Organism
Sus scrofa (Pig)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Vascular cell adhesion moleculeImported
OrganismiSus scrofa (Pig)Imported
Taxonomic identifieri9823 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaSuinaSuidaeSus

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei499 – 51921HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2020Sequence analysisAdd
BLAST
Chaini21 – 538518Sequence analysisPRO_5004203642Add
BLAST

Proteomic databases

PaxDbiQ28939.

Expressioni

Gene expression databases

GenevisibleiQ28939. SS.

Interactioni

Protein-protein interaction databases

STRINGi9823.ENSSSCP00000007316.

Structurei

3D structure databases

ProteinModelPortaliQ28939.
SMRiQ28939. Positions 26-221.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini2 – 112111Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST
Domaini224 – 30582Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST
Domaini310 – 39485Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST
Domaini399 – 48385Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST

Keywords - Domaini

Immunoglobulin domainUniRule annotationSAAS annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IIKS. Eukaryota.
ENOG4111F4V. LUCA.
HOGENOMiHOG000004820.
HOVERGENiHBG053965.
KOiK06527.

Family and domain databases

Gene3Di2.60.40.10. 5 hits.
InterProiIPR003987. ICAM_VCAM_N.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR008424. Ig_C2-set.
IPR013098. Ig_I-set.
IPR003599. Ig_sub.
IPR003598. Ig_sub2.
IPR013151. Immunoglobulin.
IPR003989. VCAM-1.
[Graphical view]
PfamiPF05790. C2-set. 1 hit.
PF07679. I-set. 1 hit.
PF00047. ig. 1 hit.
[Graphical view]
PRINTSiPR01472. ICAMVCAM1.
PR01474. VCAM1.
SMARTiSM00409. IG. 4 hits.
SM00408. IGc2. 4 hits.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 5 hits.
PROSITEiPS50835. IG_LIKE. 4 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q28939-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPRNIVVIFG ASNILWMVFA VSQNVKVEIF PEDKMIAQIG DSASLTCSAP
60 70 80 90 100
DCESSLSFSW RTQIDSPLNG KVKTNGTRST LVMNPVSFEN EHSYLCTVSC
110 120 130 140 150
GNLKGERGIQ VEIYSFPKDP EIHWSSLPEV GKPVTVRCLV PDVYPVEKLE
160 170 180 190 200
IELLKDNHSM VSQNFLELID IKSKETKSLE FTFTPTEEDI GKAIVCQATL
210 220 230 240 250
IIDGQPSVKT TPEKMQVYIS PKDPVISVNP STSLQEGDSM MMTCTSEGLP
260 270 280 290 300
APQISWSKKL DNGDQQLLSG NATLTLIAMR MEDSGIYVCE GVNPVGTNRK
310 320 330 340 350
EVELTVQVAP RDTTISVNPS STLEEGSSVN MTCSSDGFPA PKILWSKKLR
360 370 380 390 400
DGNLEPLSEN TTLTLTSTKM EDSGIYVCEG INQAGINRKE VELIIQAAPK
410 420 430 440 450
DLQLTAFPSE SVKEGDTVII SCTCGNVPPT LIILKKKAET GDTVLKSTDG
460 470 480 490 500
AYTIHRARLA DAGVYECESK NEIGLQLRSI TLDVKGRESN KDYFSSELLV
510 520 530
LYCASSLIIP AIGVIIYFAR KANMRGSYSL VDAQKSKV
Length:538
Mass (Da):58,795
Last modified:November 1, 1996 - v1
Checksum:iEC29D11B224F7261
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U08351 mRNA. Translation: AAA21542.1.
PIRiJC2457.
RefSeqiNP_999056.1. NM_213891.1.
UniGeneiSsc.14522.

Genome annotation databases

GeneIDi396925.
KEGGissc:396925.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U08351 mRNA. Translation: AAA21542.1.
PIRiJC2457.
RefSeqiNP_999056.1. NM_213891.1.
UniGeneiSsc.14522.

3D structure databases

ProteinModelPortaliQ28939.
SMRiQ28939. Positions 26-221.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9823.ENSSSCP00000007316.

Proteomic databases

PaxDbiQ28939.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi396925.
KEGGissc:396925.

Organism-specific databases

CTDi7412.

Phylogenomic databases

eggNOGiENOG410IIKS. Eukaryota.
ENOG4111F4V. LUCA.
HOGENOMiHOG000004820.
HOVERGENiHBG053965.
KOiK06527.

Gene expression databases

GenevisibleiQ28939. SS.

Family and domain databases

Gene3Di2.60.40.10. 5 hits.
InterProiIPR003987. ICAM_VCAM_N.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR008424. Ig_C2-set.
IPR013098. Ig_I-set.
IPR003599. Ig_sub.
IPR003598. Ig_sub2.
IPR013151. Immunoglobulin.
IPR003989. VCAM-1.
[Graphical view]
PfamiPF05790. C2-set. 1 hit.
PF07679. I-set. 1 hit.
PF00047. ig. 1 hit.
[Graphical view]
PRINTSiPR01472. ICAMVCAM1.
PR01474. VCAM1.
SMARTiSM00409. IG. 4 hits.
SM00408. IGc2. 4 hits.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 5 hits.
PROSITEiPS50835. IG_LIKE. 4 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Cloning and expression kinetics of porcine vascular cell adhesion molecule."
    Tsang Y.T.M., Haskard D.O., Robinson M.K.
    Biochem. Biophys. Res. Commun. 201:805-812(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: AortaImported.
  2. Tsang Y.T.M.
    Submitted (APR-1994) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: AortaImported.

Entry informationi

Entry nameiQ28939_PIG
AccessioniPrimary (citable) accession number: Q28939
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: May 11, 2016
This is version 107 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.