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Protein
Submitted name:

p-selectin

Gene
N/A
Organism
Oryctolagus cuniculus (Rabbit)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandLectinImported

Names & Taxonomyi

Protein namesi
Submitted name:
p-selectinImported
OrganismiOryctolagus cuniculus (Rabbit)Imported
Taxonomic identifieri9986 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresLagomorphaLeporidaeOryctolagus

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei591 – 614HelicalSequence analysisAdd BLAST24

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi185 ↔ 194PROSITE-ProRule annotation
Disulfide bondi230 ↔ 257PROSITE-ProRule annotation
Disulfide bondi292 ↔ 319PROSITE-ProRule annotation
Disulfide bondi357 ↔ 384PROSITE-ProRule annotation
Disulfide bondi419 ↔ 446PROSITE-ProRule annotation
Disulfide bondi491 ↔ 518PROSITE-ProRule annotation
Disulfide bondi553 ↔ 580PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliQ28657.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini39 – 159C-type lectinInterPro annotationAdd BLAST121
Domaini159 – 195EGF-likeInterPro annotationAdd BLAST37
Domaini211 – 259Sushi (CCP/SCR)InterPro annotationAdd BLAST49
Domaini260 – 321Sushi (CCP/SCR)InterPro annotationAdd BLAST62
Domaini335 – 386Sushi (CCP/SCR)InterPro annotationAdd BLAST52
Domaini387 – 448Sushi (CCP/SCR)InterPro annotationAdd BLAST62
Domaini459 – 520Sushi (CCP/SCR)InterPro annotationAdd BLAST62
Domaini521 – 582Sushi (CCP/SCR)InterPro annotationAdd BLAST62

Keywords - Domaini

EGF-like domainPROSITE-ProRule annotationSAAS annotation, RepeatSAAS annotation, SushiPROSITE-ProRule annotation, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

HOVERGENiHBG052375.
KOiK06496.

Family and domain databases

CDDicd00033. CCP. 6 hits.
cd03592. CLECT_selectins_like. 1 hit.
Gene3Di3.10.100.10. 1 hit.
InterProiView protein in InterPro
IPR001304. C-type_lectin-like.
IPR016186. C-type_lectin-like/link.
IPR018378. C-type_lectin_CS.
IPR016187. CTDL_fold.
IPR013032. EGF-like_CS.
IPR000742. EGF-like_dom.
IPR033991. Selectin_CTLD.
IPR002396. Selectin_superfamily.
IPR000436. Sushi_SCR_CCP_dom.
PfamiView protein in Pfam
PF00008. EGF. 1 hit.
PF00059. Lectin_C. 1 hit.
PF00084. Sushi. 6 hits.
PRINTSiPR00343. SELECTIN.
SMARTiView protein in SMART
SM00032. CCP. 6 hits.
SM00034. CLECT. 1 hit.
SM00181. EGF. 2 hits.
SUPFAMiSSF56436. SSF56436. 1 hit.
SSF57535. SSF57535. 6 hits.
PROSITEiView protein in PROSITE
PS00615. C_TYPE_LECTIN_1. 1 hit.
PS50041. C_TYPE_LECTIN_2. 1 hit.
PS00022. EGF_1. 1 hit.
PS01186. EGF_2. 1 hit.
PS50026. EGF_3. 1 hit.
PS50923. SUSHI. 6 hits.

Sequencei

Sequence statusi: Complete.

Q28657-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASCPKAIWN WRFQRAVFRT VQLLCFSVLI FEVINQKEVS AWTYHYSNKT
60 70 80 90 100
YSWNYSRAFC QKYYTDLVAI QNKNEIDYLN ETIPYYNSYY WIGIRKDQQI
110 120 130 140 150
NGTWVGNKNL TEEAENWADN EPNNKRNNQD CVEIYIKSLS APGKWNDEPC
160 170 180 190 200
WKRKRALCYR ASCQDMSCSK QGECIETIGN YTCSCYPGFY GPECEYVREW
210 220 230 240 250
ASLDLPQHVH MNCSHPLGNF SFNSHCSFHC ADGYALNGPS ELECLASGIW
260 270 280 290 300
TNSPPQCVAV QCPALKSPEQ GSMSCVQSAE AFQHQSSCSF SCEEGFELVG
310 320 330 340 350
PEVVHCTALG VWTAPTPVCK ALQCQDLPTS TKARVNCSHP FGDFRYQSIW
360 370 380 390 400
SFHVVHCDEG SFLVGASVLQ CLDTGNWDAP FPECQAVTCA ALPNPQNGEK
410 420 430 440 450
TCVQPLGGSS YESTCWFTCH EGFPLSGPER LDCTPSGHWT GSPPTCEEVD
460 470 480 490 500
TVSAPAPGVQ CPTLIAPKEG TMSCQHHVRN FGLNTTCHFG CKAGFTLLGD
510 520 530 540 550
SALQCRPSRQ WTAAAPTCRA VKCAKLPVTE PIVMNCSNPW GNFSYGSTCS
560 570 580 590 600
FHCPEGQLLN GSERTVCQEN VQWSTTMPTC QAGPLTIQET LTYVGGAAAG
610 620 630 640
TTGLVTGSIL LALLRRRCRQ KDDGKSPLNP QSHLGTYGVF TNAAFDPSP
Length:649
Mass (Da):71,756
Last modified:November 1, 1996 - v1
Checksum:iECCD8C847B84BC31
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U39446 mRNA. Translation: AAA81385.1.
RefSeqiNP_001076224.1. NM_001082755.1.
UniGeneiOcu.2038.

Genome annotation databases

GeneIDi100009534.
KEGGiocu:100009534.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U39446 mRNA. Translation: AAA81385.1.
RefSeqiNP_001076224.1. NM_001082755.1.
UniGeneiOcu.2038.

3D structure databases

ProteinModelPortaliQ28657.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi100009534.
KEGGiocu:100009534.

Organism-specific databases

CTDi6403.

Phylogenomic databases

HOVERGENiHBG052375.
KOiK06496.

Family and domain databases

CDDicd00033. CCP. 6 hits.
cd03592. CLECT_selectins_like. 1 hit.
Gene3Di3.10.100.10. 1 hit.
InterProiView protein in InterPro
IPR001304. C-type_lectin-like.
IPR016186. C-type_lectin-like/link.
IPR018378. C-type_lectin_CS.
IPR016187. CTDL_fold.
IPR013032. EGF-like_CS.
IPR000742. EGF-like_dom.
IPR033991. Selectin_CTLD.
IPR002396. Selectin_superfamily.
IPR000436. Sushi_SCR_CCP_dom.
PfamiView protein in Pfam
PF00008. EGF. 1 hit.
PF00059. Lectin_C. 1 hit.
PF00084. Sushi. 6 hits.
PRINTSiPR00343. SELECTIN.
SMARTiView protein in SMART
SM00032. CCP. 6 hits.
SM00034. CLECT. 1 hit.
SM00181. EGF. 2 hits.
SUPFAMiSSF56436. SSF56436. 1 hit.
SSF57535. SSF57535. 6 hits.
PROSITEiView protein in PROSITE
PS00615. C_TYPE_LECTIN_1. 1 hit.
PS50041. C_TYPE_LECTIN_2. 1 hit.
PS00022. EGF_1. 1 hit.
PS01186. EGF_2. 1 hit.
PS50026. EGF_3. 1 hit.
PS50923. SUSHI. 6 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiQ28657_RABIT
AccessioniPrimary (citable) accession number: Q28657
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: April 12, 2017
This is version 99 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.