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Protein
Submitted name:

Glibenclamide-sensitive voltage-gated potassium channel

Gene

Kv1.3-glyb

Organism
Oryctolagus cuniculus (Rabbit)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ion channel, Potassium channelSAAS annotation, Voltage-gated channelSAAS annotation

Keywords - Biological processi

Ion transport, Potassium transport, Transport

Keywords - Ligandi

Potassium

Names & Taxonomyi

Protein namesi
Submitted name:
Glibenclamide-sensitive voltage-gated potassium channelImported
Gene namesi
Name:Kv1.3-glybImported
OrganismiOryctolagus cuniculus (Rabbit)Imported
Taxonomic identifieri9986 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresLagomorphaLeporidaeOryctolagus

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei177 – 197HelicalSequence analysisAdd BLAST21
Transmembranei236 – 256HelicalSequence analysisAdd BLAST21
Transmembranei339 – 360HelicalSequence analysisAdd BLAST22
Transmembranei400 – 421HelicalSequence analysisAdd BLAST22

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Structurei

3D structure databases

ProteinModelPortaliQ28656.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini45 – 145BTB (POZ)InterPro annotationAdd BLAST101

Sequence similaritiesi

Belongs to the potassium channel family.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

HOVERGENiHBG052230.
KOiK04876.

Family and domain databases

Gene3Di1.20.120.350. 1 hit.
InterProiIPR000210. BTB/POZ_dom.
IPR027359. Channel_four-helix_dom.
IPR005821. Ion_trans_dom.
IPR003968. K_chnl_volt-dep_Kv.
IPR003972. K_chnl_volt-dep_Kv1.
IPR004050. K_chnl_volt-dep_Kv1.3.
IPR011333. SKP1/BTB/POZ.
IPR003131. T1-type_BTB.
IPR028325. VG_K_chnl.
[Graphical view]
PANTHERiPTHR11537. PTHR11537. 1 hit.
PfamiPF02214. BTB_2. 1 hit.
PF00520. Ion_trans. 1 hit.
[Graphical view]
PRINTSiPR00169. KCHANNEL.
PR01510. KV13CHANNEL.
PR01491. KVCHANNEL.
PR01496. SHAKERCHANEL.
SMARTiSM00225. BTB. 1 hit.
[Graphical view]
SUPFAMiSSF54695. SSF54695. 1 hit.

Sequencei

Sequence statusi: Complete.

Q28656-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTVVPGDHLL EPEAADGGGG PPQGGGAGCD RYEPLPAGEQ ECCGERVVIN
60 70 80 90 100
ISGVRFETQL KTLCQFPETL LGDPKRRMRY FDPVRNEYFF DRNRPSFDAI
110 120 130 140 150
LYYYQSGGRI RRPVNVPIDI FSEEIRFYQL GEEAMEKFRE DEGFLREEER
160 170 180 190 200
PLPRRDFQRQ VWLLFEYPES SGPARGIAIV SVLVILISIV IFCLETLPEF
210 220 230 240 250
RDEKDYPAAP SQDVVEAAGN GTSGAPAGAS SFSDPFFVVE TLCIIWFSFE
260 270 280 290 300
LLVRFFACPS KATFSRNIMN LIDIVAIIPY FITLGTELAE RQGNGQQAMS
310 320 330 340 350
LAILRVIRLV RVFRIFKLSR HSKGLQILGQ TLKASMRDVG LLIFFLFIGV
360 370 380 390 400
ILFSSAVYFA EADDPTSGFS SIPDAFWWAV VTMTTVGYGD MHPVTIGGKI
410 420 430 440 450
VGSLCAIAGV LTIALPVPVI VSNFNYFYHR ETEGEEQAQY MHVGSCQHLS
460 470 480 490 500
SSAEELRKAR SNSTLSKSEY MVIEEGGMNH SAFPQTPFKT GNSTATCTTN
510
NNPNSCVNIK KIFTDV
Length:516
Mass (Da):57,431
Last modified:November 1, 1998 - v2
Checksum:i795E84998BCA7CAA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U38240 Genomic DNA. Translation: AAC24718.1.
RefSeqiNP_001164600.1. NM_001171129.1.
UniGeneiOcu.7724.

Genome annotation databases

GeneIDi100328945.
KEGGiocu:100328945.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U38240 Genomic DNA. Translation: AAC24718.1.
RefSeqiNP_001164600.1. NM_001171129.1.
UniGeneiOcu.7724.

3D structure databases

ProteinModelPortaliQ28656.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi100328945.
KEGGiocu:100328945.

Organism-specific databases

CTDi3738.

Phylogenomic databases

HOVERGENiHBG052230.
KOiK04876.

Family and domain databases

Gene3Di1.20.120.350. 1 hit.
InterProiIPR000210. BTB/POZ_dom.
IPR027359. Channel_four-helix_dom.
IPR005821. Ion_trans_dom.
IPR003968. K_chnl_volt-dep_Kv.
IPR003972. K_chnl_volt-dep_Kv1.
IPR004050. K_chnl_volt-dep_Kv1.3.
IPR011333. SKP1/BTB/POZ.
IPR003131. T1-type_BTB.
IPR028325. VG_K_chnl.
[Graphical view]
PANTHERiPTHR11537. PTHR11537. 1 hit.
PfamiPF02214. BTB_2. 1 hit.
PF00520. Ion_trans. 1 hit.
[Graphical view]
PRINTSiPR00169. KCHANNEL.
PR01510. KV13CHANNEL.
PR01491. KVCHANNEL.
PR01496. SHAKERCHANEL.
SMARTiSM00225. BTB. 1 hit.
[Graphical view]
SUPFAMiSSF54695. SSF54695. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ28656_RABIT
AccessioniPrimary (citable) accession number: Q28656
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1998
Last modified: October 5, 2016
This is version 94 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.