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Protein
Submitted name:

CGMP-gated potassium channel

Gene

Kcn1

Organism
Oryctolagus cuniculus (Rabbit)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ion channel, Potassium channelSAAS annotation, Voltage-gated channelSAAS annotation

Keywords - Biological processi

Ion transport, Potassium transport, Transport

Keywords - Ligandi

Potassium

Names & Taxonomyi

Protein namesi
Submitted name:
CGMP-gated potassium channelImported
Gene namesi
Name:Kcn1Imported
OrganismiOryctolagus cuniculus (Rabbit)Imported
Taxonomic identifieri9986 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresLagomorphaLeporidaeOryctolagus

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei431 – 45222HelicalSequence analysisAdd
BLAST
Transmembranei485 – 50521HelicalSequence analysisAdd
BLAST
Transmembranei589 – 61022HelicalSequence analysisAdd
BLAST
Transmembranei650 – 67122HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Structurei

3D structure databases

ProteinModelPortaliQ28649.
SMRiQ28649. Positions 296-682.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini297 – 399103BTB (POZ)InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the potassium channel family.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

HOVERGENiHBG052230.

Family and domain databases

Gene3Di1.20.120.350. 1 hit.
InterProiIPR000210. BTB/POZ_dom.
IPR027359. Channel_four-helix_dom.
IPR005821. Ion_trans_dom.
IPR003968. K_chnl_volt-dep_Kv.
IPR003972. K_chnl_volt-dep_Kv1.
IPR011333. SKP1/BTB/POZ.
IPR003131. T1-type_BTB.
IPR028325. VG_K_chnl.
[Graphical view]
PfamiPF02214. BTB_2. 1 hit.
PF00520. Ion_trans. 1 hit.
[Graphical view]
PRINTSiPR00169. KCHANNEL.
PR01491. KVCHANNEL.
PR01496. SHAKERCHANEL.
SMARTiSM00225. BTB. 1 hit.
[Graphical view]
SUPFAMiSSF54695. SSF54695. 1 hit.

Sequencei

Sequence statusi: Complete.

Q28649-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKTFPINTLN LDQKYSNGKT HSNSDVIIFP PSIIPQSSSF DVSSNMPRSY
60 70 80 90 100
LQVRGLRLRL AGAAGWPVSL HFRFFLPPGN PSWVCLSTPH HLVPGVVVRV
110 120 130 140 150
VRNRLSLWRN ATSSFSLPWC LETPFCQGEI SCPGPCSLFA ISSCVQDVKI
160 170 180 190 200
QGVNYFQRNK VAKTAMMFLP KVKVSQCSIR RDTCPECLLL HGSQQAAKTE
210 220 230 240 250
GLHAAFPTPL KWMCVAGKKW RLLWSIFDNS DEIQEESAYA TNFDPASPRG
260 270 280 290 300
RPGSGTFPNW KILVSDNTTH ETTFSKLPGD YTDPPGPEPV ALNEGNQRVI
310 320 330 340 350
INIAGLRFET QLRTLNQFPE TLLGAREKRM QFFDSMRNEY FFDRNRPSFD
360 370 380 390 400
GILYYYQSGG KIRRPANVPI DVFADEISFY ELAVRPWTSS GKTKASSKTL
410 420 430 440 450
RIPLPTNDFH RQFWLLFEYP VKGAPHAART VAVVSVLVVV ISITIFCLVT
460 470 480 490 500
LARVPGGQGA EGSSETPASA TNKTAFPQTM FTDPFFMVES TCIVWFTLEL
510 520 530 540 550
VLRFVVCPSK TAFYRNIMNI IDIISIIPYF ATLITELVQE TEPSAQQNMS
560 570 580 590 600
LAILRIIRLV RVFRIFKLSR HSKGLQILGQ TLKASMRELG LLIFFLFIGV
610 620 630 640 650
ILFSSAVYFA EVDEPESHFS SIPDGFWWAV VTMTTVGYGD MCPITPGGKI
660 670 680 690 700
VGTLCAIAGV LTIALPVPVI VSNFNYFYHR ETENEEKQNI PGEIDKILNS
710 720
VGSRMGSTDS LSKTNGGCSP EKPRK
Length:725
Mass (Da):80,965
Last modified:November 1, 1996 - v1
Checksum:i09C538F7BFE4ED8D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U38182 mRNA. Translation: AAA92054.1.
UniGeneiOcu.2055.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U38182 mRNA. Translation: AAA92054.1.
UniGeneiOcu.2055.

3D structure databases

ProteinModelPortaliQ28649.
SMRiQ28649. Positions 296-682.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOVERGENiHBG052230.

Family and domain databases

Gene3Di1.20.120.350. 1 hit.
InterProiIPR000210. BTB/POZ_dom.
IPR027359. Channel_four-helix_dom.
IPR005821. Ion_trans_dom.
IPR003968. K_chnl_volt-dep_Kv.
IPR003972. K_chnl_volt-dep_Kv1.
IPR011333. SKP1/BTB/POZ.
IPR003131. T1-type_BTB.
IPR028325. VG_K_chnl.
[Graphical view]
PfamiPF02214. BTB_2. 1 hit.
PF00520. Ion_trans. 1 hit.
[Graphical view]
PRINTSiPR00169. KCHANNEL.
PR01491. KVCHANNEL.
PR01496. SHAKERCHANEL.
SMARTiSM00225. BTB. 1 hit.
[Graphical view]
SUPFAMiSSF54695. SSF54695. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ28649_RABIT
AccessioniPrimary (citable) accession number: Q28649
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: September 7, 2016
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.