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Q28629 (Q28629_RABIT) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 100. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein attributes

Sequence length376 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Cell surface adhesion protein. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia By similarity. PIRNR PIRNR002421

Sequence similarities

Belongs to the selectin/LECAM family. PIRNR PIRNR002421

Contains C-type lectin domain. SAAS SAAS001304

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 3838 Potential EMBL AAA67896.1
Chain39 – 376338L-selectin EMBL AAA67896.1
PRO_5000144599

Sequences

Sequence LengthMass (Da)Tools
Q28629 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 59F6AD530F490947

FASTA37642,346
        10         20         30         40         50         60 
MIFPWKCQSP QRGLWNVFKL WVWATLCCDF LAYHGTNCWT YHYSEKPMNW ERARKFCREN 

        70         80         90        100        110        120 
YTDLVAIQNK GEIEYLEKTL PFSRSYYWIG IRKIGNIWTW VGTNKSLTAE AENWGEGEPN 

       130        140        150        160        170        180 
NKKTKEDCVE IYIKRLRDSG KWNDDSCQKR KAALCYTASC HPGSCSGHGE CVEVINNYTC 

       190        200        210        220        230        240 
SCDVGYYGPQ CQFVMQCEPL EAPELGTMAC THPLGEFSFS SQCGFSCLEG TNLTGIEETT 

       250        260        270        280        290        300 
CGPLGNWSSL RPTCQVIQCE PLTAPDLGTI DCSHPRAVFG FTSTCTFSCS EGAELIGMKK 

       310        320        330        340        350        360 
TVCGSSGIWS SPTPKCQKVD RSFSMIKEGD YNPLFIPVAV MVTAFSGLAF IIWLARRLKK 

       370 
GKKSQKSKDD ILIHPL 

« Hide

References

« Hide 'large scale' references
[1]"cDNA for rabbit L-selectin."
Qian J., Marks R.M.
Submitted (MAY-1995) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Tissue: Kidney EMBL AAA67896.1.
[2]"Cloning of the cDNA for rabbit L-selectin and expression of recombinant protein with a kinase target site to facilitate radiolabeling."
Qian J., Huang X., Marks R.M.
Biochem. Biophys. Res. Commun. 225:406-412(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
[3]"Genome Sequence of Oryctolagus cuniculus (European rabbit)."
The Genome Sequencing Platform
Di Palma F., Heiman D., Young S., Gnerre S., Johnson J., Lander E.S., Lindblad-Toh K.
Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Thorbecke Ensembl ENSOCUP00000017151.
[4]"A high-resolution map of human evolutionary constraint using 29 mammals."
Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S., Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B., Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J. expand/collapse author list , Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M., Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M., Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D., Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J., Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S., Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A., Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R., Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R., Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C., Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E., Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N., Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.
Nature 478:476-482(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Thorbecke.
[5]Ensembl
Submitted (SEP-2011) to UniProtKB
Cited for: IDENTIFICATION.
Strain: Thorbecke Ensembl ENSOCUP00000017151.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AAGW02000040 Genomic DNA. No translation available.
AAGW02000041 Genomic DNA. No translation available.
U26535 mRNA. Translation: AAA67896.1.
PIRJC4892.
RefSeqNP_001075821.1. NM_001082352.1.
UniGeneOcu.2027.

3D structure databases

ProteinModelPortalQ28629.
SMRQ28629. Positions 39-194.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING9986.ENSOCUP00000017151.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSOCUT00000029156; ENSOCUP00000017151; ENSOCUG00000017432.
GeneID100009204.

Organism-specific databases

CTD6402.

Phylogenomic databases

eggNOGNOG258998.
GeneTreeENSGT00750000117319.
HOGENOMHOG000236254.
HOVERGENHBG052375.
TreeFamTF326910.

Family and domain databases

Gene3D3.10.100.10. 1 hit.
InterProIPR001304. C-type_lectin.
IPR016186. C-type_lectin-like.
IPR018378. C-type_lectin_CS.
IPR016187. C-type_lectin_fold.
IPR000742. EG-like_dom.
IPR013032. EGF-like_CS.
IPR016348. L-selectin.
IPR002396. Selectin_superfamily.
IPR000436. Sushi_SCR_CCP.
[Graphical view]
PfamPF00008. EGF. 1 hit.
PF00059. Lectin_C. 1 hit.
PF00084. Sushi. 2 hits.
[Graphical view]
PIRSFPIRSF002421. L-selectin. 1 hit.
PRINTSPR00343. SELECTIN.
SMARTSM00032. CCP. 2 hits.
SM00034. CLECT. 1 hit.
SM00181. EGF. 1 hit.
[Graphical view]
SUPFAMSSF56436. SSF56436. 1 hit.
SSF57535. SSF57535. 2 hits.
PROSITEPS00615. C_TYPE_LECTIN_1. 1 hit.
PS50041. C_TYPE_LECTIN_2. 1 hit.
PS00022. EGF_1. 1 hit.
PS01186. EGF_2. 1 hit.
PS50026. EGF_3. 1 hit.
PS50923. SUSHI. 2 hits.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ28629_RABIT
AccessionPrimary (citable) accession number: Q28629
Secondary accession number(s): G1TJM3
Entry history
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: July 9, 2014
This is version 100 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)