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Protein
Submitted name:

ABC-transporter

Gene

TAP2

Organism
Gorilla gorilla (western gorilla)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi503 – 510ATPPROSITE-ProRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandATP-bindingPROSITE-ProRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
ABC-transporterImported
Gene namesi
Name:TAP2Imported
OrganismiGorilla gorilla (western gorilla)Imported
Taxonomic identifieri9593 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeGorilla

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei56 – 79HelicalSequence analysisAdd BLAST24
Transmembranei99 – 119HelicalSequence analysisAdd BLAST21
Transmembranei149 – 169HelicalSequence analysisAdd BLAST21
Transmembranei189 – 208HelicalSequence analysisAdd BLAST20

Keywords - Cellular componenti

Membrane

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliQ28438
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini153 – 435ABC transmembrane type-1InterPro annotationAdd BLAST283
Domaini468 – 702ABC transporterInterPro annotationAdd BLAST235

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG0058 Eukaryota
COG1132 LUCA
HOVERGENiHBG008358

Family and domain databases

Gene3Di1.20.1560.10, 1 hit
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR011527 ABC1_TM_dom
IPR036640 ABC1_TM_sf
IPR013305 ABC_Tap-like
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR027417 P-loop_NTPase
IPR005293 Tap2/ABCB3
PfamiView protein in Pfam
PF00664 ABC_membrane, 1 hit
PF00005 ABC_tran, 1 hit
PRINTSiPR01897 TAP2PROTEIN
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
SSF90123 SSF90123, 1 hit
TIGRFAMsiTIGR00958 3a01208, 1 hit
PROSITEiView protein in PROSITE
PS50929 ABC_TM1F, 1 hit
PS00211 ABC_TRANSPORTER_1, 1 hit
PS50893 ABC_TRANSPORTER_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q28438-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRLPDLRPWT SLLLVDAALL WLLQGPLGTL LPQGLPGLWL EGTLRLGGLW
60 70 80 90 100
GLLKLRGLLG FVGTLLLPLC LATPLTVSLR ALVAGASRAP PARVASAPWS
110 120 130 140 150
WLLVGYGAAG LSWSLWAVLS PPGAQEKEQD QVNNKVLMWR LLKLSRPDLP
160 170 180 190 200
LLVAAFFFLV LAVLGETLIP RYSGRVIDIL GGDFDPHAFA SAIFLMCLFS
210 220 230 240 250
FGSSLSAGCR GGCFTYTMSR INLRIREQLF SSLLRQDLGF FQETKTGELN
260 270 280 290 300
SRLSSDTTLM SNWLPLNANV LLRSLVKVVG LYGFMLSISP RLTLLSLLHM
310 320 330 340 350
PFTIAAEKVY NTRHQAVLRE IQDAVARAGQ VVREAVGGLQ TVRSFGAEEH
360 370 380 390 400
EVCRYKEALE QCRQLYWRRD LECALYVLVR RVLHLGVQML MLSCGLQQMQ
410 420 430 440 450
DGELTQGSLL SFMIYQESVG SYVQTLVYIY GDMLSNVGAA EKVFSYMDRQ
460 470 480 490 500
PNLPSPGTLA PTTLQGVVKF QDVSFAYPNR PDRPVLKGLT FTLRRGEVTA
510 520 530 540 550
LVGPNGSGKS TVAALLQNLY QPTGGQVLLD EKPISQYEHC YLHSQVVSVG
560 570 580 590 600
QEPVLFSGSV RNNIAYGLQS CEDDKVMAAA QAAHADDFIQ EMEHGIYTDV
610 620 630 640 650
GEKGSQLAAG QKQRLAIARA LVRDPRVLIL DEATSALDVQ CEQALQDWNS
660 670 680 690 700
RGDRTVLVIA HRLQTVQRAH QILVLQEGKL QKLAQLQEGQ DLYSRLAQQR

LMD
Length:703
Mass (Da):77,616
Last modified:November 1, 1996 - v1
Checksum:iEDE977DF95144D23
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L49032 mRNA Translation: AAB36585.1
RefSeqiNP_001266611.1, NM_001279682.1

Genome annotation databases

GeneIDi101135772

Similar proteinsi

Entry informationi

Entry nameiQ28438_9PRIM
AccessioniPrimary (citable) accession number: Q28438
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: May 23, 2018
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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