ID   Q283U5_9VIRU            Unreviewed;       220 AA.
AC   Q283U5; A1XX53;
DT   04-APR-2006, integrated into UniProtKB/TrEMBL.
DT   04-APR-2006, sequence version 1.
DT   27-MAR-2024, entry version 66.
DE   SubName: Full=Membrane protein {ECO:0000313|EMBL:ABK35417.1};
DE   SubName: Full=p5 {ECO:0000313|EMBL:ABB69811.1, ECO:0000313|EMBL:AGY35119.1};
GN   Name=p5a {ECO:0000313|EMBL:ABB69811.1};
GN   Synonyms=P5a {ECO:0000313|EMBL:ABK35417.1};
OS   Cystovirus phi6.
OC   Viruses; Riboviria; Orthornavirae; Duplornaviricota; Vidaverviricetes;
OC   Mindivirales; Cystoviridae; Cystovirus.
OX   NCBI_TaxID=10879 {ECO:0000313|EMBL:ABB69811.1};
RN   [1] {ECO:0000313|EMBL:ABB69811.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ATCC 21781-B1 {ECO:0000313|EMBL:ABB69811.1};
RX   PubMed=16299384; DOI=10.1534/genetics.105.051136;
RA   Duffy S., Turner P.E., Burch C.L.;
RT   "Pleiotropic costs of niche expansion in the RNA bacteriophage phi 6.";
RL   Genetics 172:751-757(2006).
RN   [2] {ECO:0000313|Proteomes:UP000240345, ECO:0000313|Proteomes:UP000240936}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=A1 {ECO:0000313|EMBL:ABI20400.1}, and S1
RC   {ECO:0000313|EMBL:ABI20404.1};
RA   Dennehy J.J., O'Keefe K.J., Duffy S., Chao L., Edwards S.V., Turner P.E.;
RT   "Greater genetic diversity among asexual, not sexual, populations of
RT   bacteriophage phi6.";
RL   Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EMBL:ABK35417.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=T1 {ECO:0000313|EMBL:ABK35433.1}, T2
RC   {ECO:0000313|EMBL:ABK35437.1}, T4 {ECO:0000313|EMBL:ABK35445.1}, Tom1
RC   {ECO:0000313|EMBL:ABK35417.1}, Tom2 {ECO:0000313|EMBL:ABK35421.1},
RC   Tom3 {ECO:0000313|EMBL:ABK35425.1}, and Tom4
RC   {ECO:0000313|EMBL:ABK35429.1};
RA   Duffy S., Burch C.L., Turner P.E.;
RT   "Lack of canalization during adaptation of the dsRNA bacteriophage phi-6 to
RT   a distantly related host.";
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
RN   [4] {ECO:0000313|EMBL:AFR52907.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=22913547; DOI=10.1186/1471-2148-12-153;
RA   Turner P.E., McBride R.C., Duffy S., Montville R., Wang L.S., Yang Y.W.,
RA   Lee S.J., Kim J.;
RT   "Evolutionary genomics of host-use in bifurcating demes of RNA virus
RT   phi-6.";
RL   BMC Evol. Biol. 12:153-153(2012).
RN   [5] {ECO:0007829|PDB:4DQ5, ECO:0007829|PDB:4DQ7}
RP   X-RAY CRYSTALLOGRAPHY (1.23 ANGSTROMS) OF 48-220 IN COMPLEX WITH
RP   N-ACETYL-D-GLUCOSAMINE.
RX   PubMed=23209446; DOI=10.1371/journal.pgen.1003102;
RA   Dessau M., Goldhill D., McBride R., McBride R.L., Turner P.E., Modis Y.;
RT   "Selective pressure causes an RNA virus to trade reproductive fitness for
RT   increased structural and thermal stability of a viral enzyme.";
RL   PLoS Genet. 8:e1003102-e1003102(2012).
RN   [6] {ECO:0000313|EMBL:AGY35119.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Fast1 {ECO:0000313|EMBL:AGY35119.1}, Fast2
RC   {ECO:0000313|EMBL:AGY35123.1}, Slow1 {ECO:0000313|EMBL:AGY35127.1},
RC   and Slow2 {ECO:0000313|EMBL:AGY35131.1};
RX   PubMed=24059872; DOI=10.1186/1471-2148-13-206;
RA   Diaz-Munoz S.L., Tenaillon O., Goldhill D., Brao K., Turner P.E., Chao L.;
RT   "Electrophoretic mobility confirms reassortment bias among geographic
RT   isolates of segmented RNA phages.";
RL   BMC Evol. Biol. 13:206-206(2013).
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DR   EMBL; DQ201338; ABB69811.1; -; Genomic_RNA.
DR   EMBL; DQ785287; ABI20400.1; -; Genomic_RNA.
DR   EMBL; DQ785288; ABI20404.1; -; Genomic_RNA.
DR   EMBL; DQ978302; ABK35417.1; -; Genomic_RNA.
DR   EMBL; DQ978303; ABK35421.1; -; Genomic_RNA.
DR   EMBL; DQ978304; ABK35425.1; -; Genomic_RNA.
DR   EMBL; DQ978305; ABK35429.1; -; Genomic_RNA.
DR   EMBL; DQ978306; ABK35433.1; -; Genomic_RNA.
DR   EMBL; DQ978307; ABK35437.1; -; Genomic_RNA.
DR   EMBL; DQ978309; ABK35445.1; -; Genomic_RNA.
DR   EMBL; JX481854; AFR52907.1; -; Genomic_RNA.
DR   EMBL; JX481857; AFR52919.1; -; Genomic_RNA.
DR   EMBL; JX481860; AFR52931.1; -; Genomic_RNA.
DR   EMBL; JX481861; AFR52935.1; -; Genomic_RNA.
DR   EMBL; JX481866; AFR52955.1; -; Genomic_RNA.
DR   EMBL; JX481867; AFR52959.1; -; Genomic_RNA.
DR   EMBL; JX481868; AFR52963.1; -; Genomic_RNA.
DR   EMBL; JX481869; AFR52967.1; -; Genomic_RNA.
DR   EMBL; JX481878; AFR53003.1; -; Genomic_RNA.
DR   EMBL; JX481879; AFR53007.1; -; Genomic_RNA.
DR   EMBL; JX481880; AFR53011.1; -; Genomic_RNA.
DR   EMBL; JX481882; AFR53019.1; -; Genomic_RNA.
DR   EMBL; JX481883; AFR53023.1; -; Genomic_RNA.
DR   EMBL; JX481885; AFR53031.1; -; Genomic_RNA.
DR   EMBL; KF615858; AGY35119.1; -; Genomic_RNA.
DR   EMBL; KF615859; AGY35123.1; -; Genomic_RNA.
DR   EMBL; KF615860; AGY35127.1; -; Genomic_RNA.
DR   EMBL; KF615861; AGY35131.1; -; Genomic_RNA.
DR   PDB; 4DQ5; X-ray; 1.40 A; A/B=48-220.
DR   PDB; 4DQ7; X-ray; 1.40 A; A/B=48-220.
DR   PDB; 4DQJ; X-ray; 1.23 A; A/B=48-220.
DR   PDBsum; 4DQ5; -.
DR   PDBsum; 4DQ7; -.
DR   PDBsum; 4DQJ; -.
DR   MEROPS; U40.001; -.
DR   Proteomes; UP000240345; Genome.
DR   Proteomes; UP000240936; Genome.
DR   Gene3D; 1.10.530.50; Peptidase U40; 1.
DR   InterPro; IPR038288; Gp5_sf.
DR   InterPro; IPR019505; Peptidase_U40.
DR   Pfam; PF10464; Peptidase_U40; 1.
PE   1: Evidence at protein level;
KW   3D-structure {ECO:0007829|PDB:4DQ5, ECO:0007829|PDB:4DQ7}.
SQ   SEQUENCE   220 AA;  24023 MW;  8827BEF9380DC74F CRC64;
     MSKDSAFAVQ YSLRALGQKV RADGVVGSET RAALDALPEN QKKAIVELQA LLPKAQSVGN
     SRVRFTTAEV DSAVARISQK IGVPASYYQF LIPIENFVVA GGFETTVSGS FRGLGQFNRQ
     TWDGLRRLGR NLPAFEEGSA QLNASLYAIG FLYLENKRAY EASFKGRVFT HEIAYLYHNQ
     GAPAAEQYLT SGRLVYPKQS EAAVAAVAAA RNQHVKESWA
//