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Q28346

- RL4_CANFA

UniProt

Q28346 - RL4_CANFA

Protein

60S ribosomal protein L4

Gene

RPL4

Organism
Canis familiaris (Dog) (Canis lupus familiaris)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 71 (01 Oct 2014)
      Sequence version 2 (23 Jan 2007)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. structural constituent of ribosome Source: InterPro

    GO - Biological processi

    1. translation Source: InterPro

    Keywords - Molecular functioni

    Ribonucleoprotein, Ribosomal protein

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    60S ribosomal protein L4
    Alternative name(s):
    60S ribosomal protein L1
    Gene namesi
    Name:RPL4
    Synonyms:RPL1
    OrganismiCanis familiaris (Dog) (Canis lupus familiaris)
    Taxonomic identifieri9615 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaCanidaeCanis
    ProteomesiUP000002254: Unplaced

    Subcellular locationi

    GO - Cellular componenti

    1. ribosome Source: UniProtKB-KW

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Initiator methioninei1 – 11RemovedBy similarity
    Chaini2 – 42142060S ribosomal protein L4PRO_0000129349Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei2 – 21N-acetylalanineBy similarity
    Modified residuei14 – 141N6-acetyllysineBy similarity
    Modified residuei106 – 1061N6-acetyllysineBy similarity
    Modified residuei259 – 2591N6-acetyllysineBy similarity
    Modified residuei300 – 3001CitrullineBy similarity
    Modified residuei333 – 3331N6-acetyllysineBy similarity
    Modified residuei353 – 3531N6-acetyllysineBy similarity
    Modified residuei361 – 3611N6-acetyllysineBy similarity
    Modified residuei362 – 3621PhosphoserineBy similarity

    Post-translational modificationi

    Citrullinated by PADI4.By similarity

    Keywords - PTMi

    Acetylation, Citrullination, Phosphoprotein

    Proteomic databases

    PaxDbiQ28346.
    PRIDEiQ28346.

    Interactioni

    Subunit structurei

    Interacts with RBM3. May bind IPO9 with low affinity By similarity.By similarity

    Protein-protein interaction databases

    STRINGi9615.ENSCAFP00000025501.

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    2ZKRelectron microscopy8.70c1-421[»]
    ProteinModelPortaliQ28346.
    SMRiQ28346. Positions 7-263.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiQ28346.

    Family & Domainsi

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi307 – 418112Lys-richAdd
    BLAST

    Sequence similaritiesi

    Belongs to the ribosomal protein L4P family.Curated

    Phylogenomic databases

    eggNOGiCOG0088.
    HOGENOMiHOG000107331.
    HOVERGENiHBG001453.
    InParanoidiQ28346.

    Family and domain databases

    Gene3Di3.40.1370.10. 1 hit.
    InterProiIPR025755. Ribos_L4_C_dom.
    IPR002136. Ribosomal_L4/L1e.
    IPR013000. Ribosomal_L4/L1e_euk/arc_CS.
    IPR023574. Ribosomal_L4_dom.
    [Graphical view]
    PfamiPF14374. Ribos_L4_asso_C. 1 hit.
    PF00573. Ribosomal_L4. 1 hit.
    [Graphical view]
    SUPFAMiSSF52166. SSF52166. 1 hit.
    PROSITEiPS00939. RIBOSOMAL_L1E. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q28346-1 [UniParc]FASTAAdd to Basket

    « Hide

    MACARPLISV YSEKGESSGK NVTLPAVFKA PIRPDIVNFV HTNLRKNNRQ    50
    PYAVSELAGH QTSAESWGTG RAVARIPRVR GGGTHRSGQG AFGNMCRGGR 100
    MFAPTKTWRR WHRRVNTTQK RYAICSALAC LSLPALVMSK GHRIEEVPEL 150
    PLVVEDKVEG YKKTKEAVLL LKKLKAWNDI KKVYASQRMR AGKGKMRNRR 200
    RIQRRGPCII YNEDNGIIKA FRKHPGITLL NVSKLNILKL APGGHVGRFC 250
    IWTESAFRKL DDLYGTWRKA ASLKSNYNLP MHKMLNTDLS RILKMPRDPR 300
    ALRAPRKKIH RRVLKKNPLK NLRIMLKLNP YAKTMRRNTI LRQAKNHKLR 350
    MDKAAAALEA KSEEKGVPGK KPRRKKGKKT VGVKKPKKPV VGKKAAATKK 400
    PAADKKPAEK KPTTEEKKPA A 421
    Length:421
    Mass (Da):47,515
    Last modified:January 23, 2007 - v2
    Checksum:iAF08C4DDA50A435B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X99909 mRNA. Translation: CAA68182.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X99909 mRNA. Translation: CAA68182.1 .

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    2ZKR electron microscopy 8.70 c 1-421 [» ]
    ProteinModelPortali Q28346.
    SMRi Q28346. Positions 7-263.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 9615.ENSCAFP00000025501.

    Proteomic databases

    PaxDbi Q28346.
    PRIDEi Q28346.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    eggNOGi COG0088.
    HOGENOMi HOG000107331.
    HOVERGENi HBG001453.
    InParanoidi Q28346.

    Miscellaneous databases

    EvolutionaryTracei Q28346.

    Family and domain databases

    Gene3Di 3.40.1370.10. 1 hit.
    InterProi IPR025755. Ribos_L4_C_dom.
    IPR002136. Ribosomal_L4/L1e.
    IPR013000. Ribosomal_L4/L1e_euk/arc_CS.
    IPR023574. Ribosomal_L4_dom.
    [Graphical view ]
    Pfami PF14374. Ribos_L4_asso_C. 1 hit.
    PF00573. Ribosomal_L4. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52166. SSF52166. 1 hit.
    PROSITEi PS00939. RIBOSOMAL_L1E. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Sandholzer U.
      Submitted (AUG-1996) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 2-421.
      Strain: Mongrel.
    2. Cited for: STRUCTURE BY ELECTRON MICROSCOPY (8.7 ANGSTROMS).

    Entry informationi

    Entry nameiRL4_CANFA
    AccessioniPrimary (citable) accession number: Q28346
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1997
    Last sequence update: January 23, 2007
    Last modified: October 1, 2014
    This is version 71 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome, Reference proteome

    Documents

    1. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    2. Ribosomal proteins
      Ribosomal proteins families and list of entries
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3