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Protein

C-type lectin domain family 3 member A

Gene

CLEC3A

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Promotes cell adhesion to laminin and fibronectin.By similarity

GO - Molecular functioni

Keywordsi

LigandLectin

Names & Taxonomyi

Protein namesi
Recommended name:
C-type lectin domain family 3 member A
Alternative name(s):
C-type lectin superfamily member 1
Cartilage-derived C-type lectin
Gene namesi
Name:CLEC3A
Synonyms:CLECSF1
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 18

Organism-specific databases

VGNCiVGNC:27428 CLEC3A

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24Sequence analysisAdd BLAST24
ChainiPRO_000001737325 – 197C-type lectin domain family 3 member AAdd BLAST173

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi68 ↔ 78PROSITE-ProRule annotation
Disulfide bondi95 ↔ 191PROSITE-ProRule annotation
Disulfide bondi167 ↔ 183PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond

Proteomic databases

PaxDbiQ28008
PRIDEiQ28008

Expressioni

Gene expression databases

BgeeiENSBTAG00000046772

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000054542

Structurei

3D structure databases

ProteinModelPortaliQ28008
SMRiQ28008
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini74 – 192C-type lectinPROSITE-ProRule annotationAdd BLAST119

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiKOG4297 Eukaryota
ENOG410XPJ1 LUCA
GeneTreeiENSGT00610000086061
HOGENOMiHOG000060248
HOVERGENiHBG108270
InParanoidiQ28008
KOiK17519
OMAiKRYICEF
OrthoDBiEOG091G0NMQ
TreeFamiTF330481

Family and domain databases

Gene3Di3.10.100.10, 1 hit
InterProiView protein in InterPro
IPR001304 C-type_lectin-like
IPR016186 C-type_lectin-like/link_sf
IPR018378 C-type_lectin_CS
IPR016187 CTDL_fold
PfamiView protein in Pfam
PF00059 Lectin_C, 1 hit
SMARTiView protein in SMART
SM00034 CLECT, 1 hit
SUPFAMiSSF56436 SSF56436, 1 hit
PROSITEiView protein in PROSITE
PS00615 C_TYPE_LECTIN_1, 1 hit
PS50041 C_TYPE_LECTIN_2, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q28008-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKNGLVIYI LVITLLLDQT SCHASKFKAR KHSKRRVKEK DGDLKTQVEK
60 70 80 90 100
LWREVNALKE MQALQTVCLR GTKFHKKCYL AAEGLKHFHE ANEDCISKGG
110 120 130 140 150
TLVVPRSADE INALRDYGKR SLPGVNDFWL GINDMVAEGK FVDINGLAIS
160 170 180 190
FLNWDQAQPN GGKRENCALF SQSAQGKWSD EACHSSKRYI CEFTIPQ
Length:197
Mass (Da):22,216
Last modified:November 1, 1996 - v1
Checksum:iAAAC4280F41AC0F4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U22298 mRNA Translation: AAC18614.1
RefSeqiNP_777058.1, NM_174633.2
UniGeneiBt.33

Genome annotation databases

EnsembliENSBTAT00000064491; ENSBTAP00000054542; ENSBTAG00000046772
GeneIDi282415
KEGGibta:282415

Similar proteinsi

Entry informationi

Entry nameiCLC3A_BOVIN
AccessioniPrimary (citable) accession number: Q28008
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 15, 2005
Last sequence update: November 1, 1996
Last modified: March 28, 2018
This is version 97 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health