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Protein
Submitted name:

BA14

Gene
N/A
Organism
Bos taurus (Bovine)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei2377 – 23771SubstrateUniRule annotation
Active sitei2407 – 24071Phosphocysteine intermediateUniRule annotation
Binding sitei2451 – 24511SubstrateUniRule annotation

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
BA14Imported
OrganismiBos taurus (Bovine)Imported
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiQ28006.

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000051288.

Structurei

3D structure databases

ProteinModelPortaliQ28006.
SMRiQ28006. Positions 1358-1459, 2169-2476.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini3 – 189187KINDInterPro annotationAdd
BLAST
Domaini572 – 872301FERMInterPro annotationAdd
BLAST
Domaini1093 – 117987PDZ (DHR)InterPro annotationAdd
BLAST
Domaini1368 – 145386PDZ (DHR)InterPro annotationAdd
BLAST
Domaini1499 – 158789PDZ (DHR)InterPro annotationAdd
BLAST
Domaini1787 – 186882PDZ (DHR)InterPro annotationAdd
BLAST
Domaini1882 – 196584PDZ (DHR)InterPro annotationAdd
BLAST
Domaini2212 – 2466255Tyrosine-protein phosphataseInterPro annotationAdd
BLAST
Domaini2388 – 245770TYR_PHOSPHATASE_2InterPro annotationAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni2407 – 24137Substrate bindingUniRule annotation

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili473 – 50028Sequence analysisAdd
BLAST
Coiled coili1763 – 179028Sequence analysisAdd
BLAST

Sequence similaritiesi

Contains 5 PDZ (DHR) domains.UniRule annotation
Contains FERM domain.SAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0789. Eukaryota.
COG5599. LUCA.
HOGENOMiHOG000115774.
HOVERGENiHBG053756.
KOiK02374.

Family and domain databases

Gene3Di1.20.80.10. 1 hit.
2.30.29.30. 1 hit.
2.30.42.10. 5 hits.
3.90.190.10. 1 hit.
InterProiIPR019749. Band_41_domain.
IPR014352. FERM/acyl-CoA-bd_prot_3-hlx.
IPR019748. FERM_central.
IPR000299. FERM_domain.
IPR018979. FERM_N.
IPR018980. FERM_PH-like_C.
IPR011019. KIND_dom.
IPR001478. PDZ.
IPR011993. PH_dom-like.
IPR029021. Prot-tyrosine_phosphatase-like.
IPR000242. PTPase_domain.
IPR012153. PTPN13.
IPR003595. Tyr_Pase_cat.
IPR000387. TYR_PHOSPHATASE_dom.
IPR029071. Ubiquitin-rel_dom.
[Graphical view]
PANTHERiPTHR19134:SF197. PTHR19134:SF197. 2 hits.
PfamiPF09380. FERM_C. 1 hit.
PF00373. FERM_M. 1 hit.
PF09379. FERM_N. 1 hit.
PF00595. PDZ. 5 hits.
PF00102. Y_phosphatase. 1 hit.
[Graphical view]
PIRSFiPIRSF000933. Tyr-Ptase_nr13. 1 hit.
PRINTSiPR00935. BAND41.
PR00700. PRTYPHPHTASE.
SMARTiSM00295. B41. 1 hit.
SM01196. FERM_C. 1 hit.
SM00750. KIND. 1 hit.
SM00228. PDZ. 5 hits.
SM00194. PTPc. 1 hit.
SM00404. PTPc_motif. 1 hit.
[Graphical view]
SUPFAMiSSF47031. SSF47031. 1 hit.
SSF50156. SSF50156. 5 hits.
SSF50729. SSF50729. 1 hit.
SSF52799. SSF52799. 1 hit.
SSF54236. SSF54236. 1 hit.
PROSITEiPS50057. FERM_3. 1 hit.
PS51377. KIND. 1 hit.
PS50106. PDZ. 5 hits.
PS50056. TYR_PHOSPHATASE_2. 1 hit.
PS50055. TYR_PHOSPHATASE_PTP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q28006-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHVSLAEALE VRGGPLQEEE IWAVLNQSAE SLQELFRKVS IADPAALGFI
60 70 80 90 100
ISPWSLLLRS GSVSFTDENI SNQDLRAFTA PEVLQSQSLT SLSDVEKIHI
110 120 130 140 150
YSLGMTLYWG ADHEVPQSQP IKLGDHLNSI LLGMCEDVVY ARVSVRTVLD
160 170 180 190 200
ACSAHIRNSN CAPSFSYVKQ LVKLVLGSLS GTDQLSRSSE QKPDRSQAIR
210 220 230 240 250
DRLRGKGLPT GRSSTSDVLD TYKSPSCHQA FLNKGLSKSM GFLSIKDTRD
260 270 280 290 300
EEDYFKDLSS DNNSGQEDSE SSCSPYPFKS SGPEKKAVPG LDVLPKKKIW
310 320 330 340 350
ASSMDLLCTG DRDFSSGETD RYQRRLPEAV TVRTSTTPRK KEARYSDGSL
360 370 380 390 400
ALDIFGPQKM DPAFHTRDLP TSSAISSALD RIRERQKKLR VLREAMNVEE
410 420 430 440 450
PVQRYKTYHS DLFSTSSESP SIISSESDFR QVRKSETSKR FESNSGLPGV
460 470 480 490 500
DETPSQGQSQ RPRQYETPLE GNLINQEIML KRQEEEMMQL QARMALRQSR
510 520 530 540 550
LSLYPGDTIK ASMLDITRDP LREIALETAM TQRKLRNFFG PEFVKMTIEP
560 570 580 590 600
FISLDLPRSI LTKKGKSEDN RRKVNIMLLS GQRLELTCDT KTICKDVFDM
610 620 630 640 650
VVAHIGLVEH HLFALATLKD NEYFFVDSDL KLTKVAPEGW KEEPKKKSKA
660 670 680 690 700
SINFTLFFRI KFFMDDVSLI QHTLTCHQYY LQLRKDTLEE RIHCDDETSL
710 720 730 740 750
LLASLALQAE YGDYQPEVHG VSYFRLEHYL PPRVMEKLDL SYIKEELPKL
760 770 780 790 800
HNTYMGASEK ETELEFLKVC QRLTEYGVHF HRVHPEKKSQ TGILLGVCSK
810 820 830 840 850
GVLVFEVHNG VRTLVLRFPW RETKKISFSK KKITLQNTSD GIKHAFQTDN
860 870 880 890 900
SKICQYLLHL CSSQHKFQLQ MRARQSNQDA QDIERASFRS LNFQAESVRG
910 920 930 940 950
FNMGRAVSTG SLASSTLNKL AVRPLSVQAE ILKRLSCSEL SLCQPLQNSA
960 970 980 990 1000
KEKNGKTAWE EKPRGMSKSY HDLSQACLYP HRKNVNVNME PPPQTIAELV
1010 1020 1030 1040 1050
GKTLHQMARS DTESLAGVTK LNNSKSVASL NRSPERRKHE SDSSSFEDLG
1060 1070 1080 1090 1100
QAYVLGMTLH SSGNSSSQVP LKENDVLHKR WSIASSPERE ITLVNLKKDA
1110 1120 1130 1140 1150
QYGLGFQIIG GEKMGRLDLG VFISSVTPGG PADLDGCLKP GDRLISVNSV
1160 1170 1180 1190 1200
SLEGVSHHAA VEILQNAPED VTLVISQPKE KLSKVPSTPV HMANGTKNYM
1210 1220 1230 1240 1250
KKPSHLQDGT VNSSEDHCWP RGTPRHISES SFGLSGGLRE GSLSSQDSRT
1260 1270 1280 1290 1300
ESASLSQSQV NGFFASHAAD RSWQDSQRGS PSPSVISKAT EKKWTSTDSN
1310 1320 1330 1340 1350
RSKAKNTGIS DAPDYSDRGD SDMDEATYSS SQDHHIPKKE SSSSMNTSNK
1360 1370 1380 1390 1400
MNFKTFPSSP PKPGDIFEVE LAKNDNSLGI SVTGGVNTSV RHGGIYVKAV
1410 1420 1430 1440 1450
IPKGAAESDG RIHKGDRVLA VNGVSLEGAT HKQAVETLRN TGQVVHLLLE
1460 1470 1480 1490 1500
KGQSPASKEH VLQCTVSDPD TQGQAPEKMM TKMTHVKDYS FVTEENTFEV
1510 1520 1530 1540 1550
KLLKNSSGLG FSFSREDNVI PEQMNTSIVR VKKLFPGQPA AESGQIDVGD
1560 1570 1580 1590 1600
VILKVNGASL KGLSQQEVIS ALRGTSPEVS LLLCRPPPGV LPEIDPALST
1610 1620 1630 1640 1650
PLHSPAQVPL NNSKDPPQTA CAEQGTSSDE NEMSDKNRRP CTSPSRRDSY
1660 1670 1680 1690 1700
SDSSESGEDD LAKAPAKIPN MSWSSALQQT LSNMMSQAQS HHDTLRSQED
1710 1720 1730 1740 1750
PICTMFYYPQ KVPNKPEHEG SNPLPPRPLD VTPGQSCQSQ SESVPINAMD
1760 1770 1780 1790 1800
KYHTHHTSEP TRQESLTSLK NDLENHLEDF ELEVELLITL HKSEKGSLGF
1810 1820 1830 1840 1850
TVTKGNQSIG CYVHDVIQDP AKSDGRLRPG DRLIKVNDTD VTNMTHTDAV
1860 1870 1880 1890 1900
NLLRRAPRTV RLVLGRVLEL PRMPVLPHLL PDITFTCNRE ELGFSLSGGR
1910 1920 1930 1940 1950
DSLHQVVYVS DINPRSIAAT EGNLQLLDVI HYVNGVSTQG MTLEEAKRTL
1960 1970 1980 1990 2000
DMSLPSVVLK ATRDGHPVVP SSKGSALSAS KSAKANGPHI VEPCGKPSLT
2010 2020 2030 2040 2050
PNNSFSKVNG EEIIEILYPE GKCSTYQMKE SANLILYKES DGQEDENYDD
2060 2070 2080 2090 2100
PQEAEVIQSL LDVVDEEAQN LLNQNNVAGD ACVPGALKAN EKLSEERAQD
2110 2120 2130 2140 2150
TYCDGSPLPE DFTESTKMNG CEEHCEEKGK SESLIQKSEE KKTEDDEITW
2160 2170 2180 2190 2200
GSDELPIETT DHEDSNKEHP FLTNEELTTL PIIKVLPSGK YTGAKLKSVI
2210 2220 2230 2240 2250
RMLRGLLDQG IPSKELENLQ ELKPLDQCLI GQTKENRRKN RYKNILPYDA
2260 2270 2280 2290 2300
TRVPLGDEGG YINASFIKIP VGREEFVYIA CQGPLPTTVG DFWQMIWEQN
2310 2320 2330 2340 2350
SSVIAMMTQE VEGEKIKCQR YWPNVLGKST MVSNRLRLAL VRVQQLKGFV
2360 2370 2380 2390 2400
VRAMTLEDIQ TGEVRHVSHL NFTAWPDHDT PSQPDDLLTF ISYMRHVHRS
2410 2420 2430 2440 2450
GPIITHCSAG IGRSGTLICI DVVLGLISQD LEFDISDLVR CMRLQRHGMV
2460 2470 2480
QTEDQYIFCY QVILYVLTRL QAEEEQKEQP QPLK
Length:2,484
Mass (Da):276,385
Last modified:November 1, 1996 - v1
Checksum:i45A92F0D4F1ED13D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U20807 mRNA. Translation: AAA73516.1.
RefSeqiNP_777015.2. NM_174590.3.
UniGeneiBt.64781.

Genome annotation databases

GeneIDi282333.
KEGGibta:282333.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U20807 mRNA. Translation: AAA73516.1.
RefSeqiNP_777015.2. NM_174590.3.
UniGeneiBt.64781.

3D structure databases

ProteinModelPortaliQ28006.
SMRiQ28006. Positions 1358-1459, 2169-2476.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000051288.

Proteomic databases

PaxDbiQ28006.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi282333.
KEGGibta:282333.

Organism-specific databases

CTDi5783.

Phylogenomic databases

eggNOGiKOG0789. Eukaryota.
COG5599. LUCA.
HOGENOMiHOG000115774.
HOVERGENiHBG053756.
KOiK02374.

Miscellaneous databases

NextBioi20806128.

Family and domain databases

Gene3Di1.20.80.10. 1 hit.
2.30.29.30. 1 hit.
2.30.42.10. 5 hits.
3.90.190.10. 1 hit.
InterProiIPR019749. Band_41_domain.
IPR014352. FERM/acyl-CoA-bd_prot_3-hlx.
IPR019748. FERM_central.
IPR000299. FERM_domain.
IPR018979. FERM_N.
IPR018980. FERM_PH-like_C.
IPR011019. KIND_dom.
IPR001478. PDZ.
IPR011993. PH_dom-like.
IPR029021. Prot-tyrosine_phosphatase-like.
IPR000242. PTPase_domain.
IPR012153. PTPN13.
IPR003595. Tyr_Pase_cat.
IPR000387. TYR_PHOSPHATASE_dom.
IPR029071. Ubiquitin-rel_dom.
[Graphical view]
PANTHERiPTHR19134:SF197. PTHR19134:SF197. 2 hits.
PfamiPF09380. FERM_C. 1 hit.
PF00373. FERM_M. 1 hit.
PF09379. FERM_N. 1 hit.
PF00595. PDZ. 5 hits.
PF00102. Y_phosphatase. 1 hit.
[Graphical view]
PIRSFiPIRSF000933. Tyr-Ptase_nr13. 1 hit.
PRINTSiPR00935. BAND41.
PR00700. PRTYPHPHTASE.
SMARTiSM00295. B41. 1 hit.
SM01196. FERM_C. 1 hit.
SM00750. KIND. 1 hit.
SM00228. PDZ. 5 hits.
SM00194. PTPc. 1 hit.
SM00404. PTPc_motif. 1 hit.
[Graphical view]
SUPFAMiSSF47031. SSF47031. 1 hit.
SSF50156. SSF50156. 5 hits.
SSF50729. SSF50729. 1 hit.
SSF52799. SSF52799. 1 hit.
SSF54236. SSF54236. 1 hit.
PROSITEiPS50057. FERM_3. 1 hit.
PS51377. KIND. 1 hit.
PS50106. PDZ. 5 hits.
PS50056. TYR_PHOSPHATASE_2. 1 hit.
PS50055. TYR_PHOSPHATASE_PTP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Tyrosine Phosphatases and the Cytoskeleton."
    Vega Q.C., Walton K.M., Dixon J.E.
    Submitted (FEB-1995) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ28006_BOVIN
AccessioniPrimary (citable) accession number: Q28006
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: May 11, 2016
This is version 120 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.