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Protein
Submitted name:

High affinity thiamine transport protein 1

Gene

SLC19A2

Organism
Felis catus (Cat) (Felis silvestris catus)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
High affinity thiamine transport protein 1Imported
Submitted name:
Solute carrier family 19 member 2Imported
Gene namesi
Name:SLC19A2Imported
OrganismiFelis catus (Cat) (Felis silvestris catus)
Taxonomic identifieri9685 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraFeliformiaFelidaeFelinaeFelis
Proteomesi
  • UP000011712 Componenti: Chromosome F1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei27 – 44HelicalSequence analysisAdd BLAST18
Transmembranei74 – 93HelicalSequence analysisAdd BLAST20
Transmembranei100 – 121HelicalSequence analysisAdd BLAST22
Transmembranei127 – 147HelicalSequence analysisAdd BLAST21
Transmembranei159 – 180HelicalSequence analysisAdd BLAST22
Transmembranei186 – 206HelicalSequence analysisAdd BLAST21
Transmembranei288 – 305HelicalSequence analysisAdd BLAST18
Transmembranei325 – 347HelicalSequence analysisAdd BLAST23
Transmembranei359 – 381HelicalSequence analysisAdd BLAST23
Transmembranei387 – 406HelicalSequence analysisAdd BLAST20
Transmembranei413 – 436HelicalSequence analysisAdd BLAST24
Transmembranei448 – 469HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSFCAG00000007711.

Interactioni

Protein-protein interaction databases

STRINGi9685.ENSFCAP00000007142.

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3810. Eukaryota.
ENOG410XT34. LUCA.
GeneTreeiENSGT00510000046382.
HOVERGENiHBG054198.
KOiK14610.
OMAiLVRYKPV.
OrthoDBiEOG091G0BSJ.

Family and domain databases

InterProiView protein in InterPro
IPR002666. Folate_carrier.
IPR020846. MFS_dom.
IPR028338. ThTr-1.
PANTHERiPTHR10686. PTHR10686. 1 hit.
PfamiView protein in Pfam
PF01770. Folate_carrier. 1 hit.
PIRSFiPIRSF028739. Folate_carrier. 1 hit.
PIRSF500794. Thiamine_transporter_1. 1 hit.
SUPFAMiSSF103473. SSF103473. 2 hits.
TIGRFAMsiTIGR00806. rfc. 1 hit.

Sequencei

Sequence statusi: Complete.

Q27PN5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDVPGPVSRR AAAATALLRT ARVPRECWFL PTALLCAYGF FASLRPSEPF
60 70 80 90 100
LTPYLLGPDK NLTEREVFNE IYPVWTYSYL VLLFPVFLAT DYLRYKPVIL
110 120 130 140 150
LQGLSLIVTW FMLLYAQGLL AIQFLEFFYG IATATEIAYY SYIYSVVDLT
160 170 180 190 200
MYQKVTSYCR SATLVGFTVG SVLGQILVSV AGWSLFSLNV ISLTCVSVAF
210 220 230 240 250
AVAWFLPMPQ KSLFFHHVPS TCQRTNGIKA QNGGFVTNTT AANHLPGWED
260 270 280 290 300
PESKMPLNTE EPEPTPERLL VLKVLWDDFL MCYSSRPLLC WSVWWALSTC
310 320 330 340 350
GYFQVVNYAQ GLWETVMPSR DAAIYNGGVE AVSTLLGAVA VFVVGYIKIS
360 370 380 390 400
WSTWGEMMLS LFSLLIAAAV YIMDTVQNIW VCYTSYVVFR IIYMLLITIA
410 420 430 440 450
TFQIAANLSM ERYALVFGVN TFIALVLQTL LTLIVVDASG LGLEITTQFL
460 470 480 490
IYAGYFALIA VVFLASGSVS IMKKCRKQED EESSSRVTTL
Length:490
Mass (Da):54,802
Last modified:April 4, 2006 - v1
Checksum:i9E79AB14225E132E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AANG02144303 Genomic DNA. No translation available.
AANG02144304 Genomic DNA. No translation available.
DQ391281 mRNA. Translation: ABD61002.1.
RefSeqiNP_001035045.1. NM_001039956.1.

Genome annotation databases

EnsembliENSFCAT00000007713; ENSFCAP00000007142; ENSFCAG00000007711.
GeneIDi664737.
KEGGifca:664737.

Similar proteinsi

Entry informationi

Entry nameiQ27PN5_FELCA
AccessioniPrimary (citable) accession number: Q27PN5
Entry historyiIntegrated into UniProtKB/TrEMBL: April 4, 2006
Last sequence update: April 4, 2006
Last modified: August 30, 2017
This is version 58 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported