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Q27I49

- Q27I49_PIG

UniProt

Q27I49 - Q27I49_PIG

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Protein
Submitted name: Suppressor of variegation 3-9-like protein 2
Gene
LOC100738592, SUV39H2, Suv39h2
Organism
Sus scrofa (Pig)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

Catalytic activityi

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].SAAS annotations

GO - Molecular functioni

  1. histone-lysine N-methyltransferase activity Source: InterPro
  2. zinc ion binding Source: InterPro
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Keywords - Molecular functioni

    MethyltransferaseUniRule annotationSAAS annotations, Transferase

    Keywords - Ligandi

    S-adenosyl-L-methionineSAAS annotations

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Suppressor of variegation 3-9-like protein 2Imported
    Submitted name:
    Uncharacterized proteinImported
    Gene namesi
    Name:LOC100738592Imported
    Synonyms:SUV39H2Imported, Suv39h2Imported
    OrganismiSus scrofa (Pig)Imported
    Taxonomic identifieri9823 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaSuinaSuidaeSus
    ProteomesiUP000008227: Chromosome 10, UP000008227: Unplaced

    Subcellular locationi

    Nucleus By similarity

    GO - Cellular componenti

    1. chromosome Source: UniProtKB-KW
    2. nucleus Source: UniProtKB-SubCell
    Complete GO annotation...

    Keywords - Cellular componenti

    ChromosomeSAAS annotations, NucleusUniRule annotationSAAS annotations

    Interactioni

    Protein-protein interaction databases

    STRINGi9823.ENSSSCP00000011784.

    Structurei

    3D structure databases

    ProteinModelPortaliQ27I49.
    SMRiQ27I49. Positions 64-350.

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 SET domain.UniRule annotation
    Contains 1 post-SET domain.
    Contains 1 pre-SET domain.
    Contains SET domain.SAAS annotations
    Contains post-SET domain.SAAS annotations
    Contains pre-SET domain.SAAS annotations

    Phylogenomic databases

    GeneTreeiENSGT00750000117355.
    HOVERGENiHBG055621.
    KOiK11419.
    OMAiAWCVPCL.
    OrthoDBiEOG7RJPR0.
    TreeFamiTF106452.

    Family and domain databases

    InterProiIPR023780. Chromo_domain.
    IPR000953. Chromo_domain/shadow.
    IPR016197. Chromodomain-like.
    IPR023779. Chromodomain_CS.
    IPR011381. Histone_H3-K9_MeTrfase.
    IPR003616. Post-SET_dom.
    IPR007728. Pre-SET_dom.
    IPR001214. SET_dom.
    [Graphical view]
    PfamiPF00385. Chromo. 1 hit.
    PF05033. Pre-SET. 1 hit.
    PF00856. SET. 1 hit.
    [Graphical view]
    PIRSFiPIRSF009343. SUV39_SET. 1 hit.
    SMARTiSM00298. CHROMO. 1 hit.
    SM00508. PostSET. 1 hit.
    SM00317. SET. 1 hit.
    [Graphical view]
    SUPFAMiSSF54160. SSF54160. 1 hit.
    PROSITEiPS00598. CHROMO_1. 1 hit.
    PS50013. CHROMO_2. 1 hit.
    PS50868. POST_SET. 1 hit.
    PS50867. PRE_SET. 1 hit.
    PS51579. SAM_MT43_SUVAR39_3. 1 hit.
    PS50280. SET. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q27I49-1 [UniParc]FASTAAdd to Basket

    « Hide

    MEYYLVKWKG WPDSTNTWEP LQNLKCPLLL QQFCNDKHNY LSQVKKGKAI    50
    TLKENHRALK PAIAEYIVKK AKQRIALQRW QDELNRRKNH KGMIFVENTV 100
    DLEGPPSDFY YINEYKPAPG ISLVNEATFG CSCTDCFHEK CCPAEAGVLL 150
    AYNKNQQIKI PPGTPIYECN SRCQCGPDCP NRIVQKGTQY SLCIFRTSNG 200
    CGWGVKTLVK IKRMSFVMEY VGEVITSEEA ERRGQLYDNK GITYLFDLDY 250
    ESDEFTVDAA RYGNVSHFVN HSCDPNLQVF NVFIDNLDTR LPRIALFSTR 300
    TINAGEELTF DYQMKGSGDI SSDSIDHSPA KKRARTVCKC GAVTCRGYLN 350
    Length:350
    Mass (Da):39,889
    Last modified:April 4, 2006 - v1
    Checksum:i841C83C1FDBE67D0
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CU929591 Genomic DNA. No translation available.
    DQ400534 mRNA. Translation: ABD62994.1.
    EU219913 mRNA. Translation: ABX10188.1.
    RefSeqiNP_001034836.1. NM_001039747.1.
    XP_005658692.1. XM_005658635.1.
    XP_005668176.1. XM_005668119.1.
    UniGeneiSsc.24424.

    Genome annotation databases

    EnsembliENSSSCT00000012092; ENSSSCP00000011784; ENSSSCG00000011048.
    ENSSSCT00000031746; ENSSSCP00000025189; ENSSSCG00000023928.
    GeneIDi100738592.
    664651.
    KEGGissc:100738592.
    ssc:664651.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CU929591 Genomic DNA. No translation available.
    DQ400534 mRNA. Translation: ABD62994.1 .
    EU219913 mRNA. Translation: ABX10188.1 .
    RefSeqi NP_001034836.1. NM_001039747.1.
    XP_005658692.1. XM_005658635.1.
    XP_005668176.1. XM_005668119.1.
    UniGenei Ssc.24424.

    3D structure databases

    ProteinModelPortali Q27I49.
    SMRi Q27I49. Positions 64-350.
    ModBasei Search...

    Protein-protein interaction databases

    STRINGi 9823.ENSSSCP00000011784.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSSSCT00000012092 ; ENSSSCP00000011784 ; ENSSSCG00000011048 .
    ENSSSCT00000031746 ; ENSSSCP00000025189 ; ENSSSCG00000023928 .
    GeneIDi 100738592.
    664651.
    KEGGi ssc:100738592.
    ssc:664651.

    Organism-specific databases

    CTDi 79723.

    Phylogenomic databases

    GeneTreei ENSGT00750000117355.
    HOVERGENi HBG055621.
    KOi K11419.
    OMAi AWCVPCL.
    OrthoDBi EOG7RJPR0.
    TreeFami TF106452.

    Family and domain databases

    InterProi IPR023780. Chromo_domain.
    IPR000953. Chromo_domain/shadow.
    IPR016197. Chromodomain-like.
    IPR023779. Chromodomain_CS.
    IPR011381. Histone_H3-K9_MeTrfase.
    IPR003616. Post-SET_dom.
    IPR007728. Pre-SET_dom.
    IPR001214. SET_dom.
    [Graphical view ]
    Pfami PF00385. Chromo. 1 hit.
    PF05033. Pre-SET. 1 hit.
    PF00856. SET. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF009343. SUV39_SET. 1 hit.
    SMARTi SM00298. CHROMO. 1 hit.
    SM00508. PostSET. 1 hit.
    SM00317. SET. 1 hit.
    [Graphical view ]
    SUPFAMi SSF54160. SSF54160. 1 hit.
    PROSITEi PS00598. CHROMO_1. 1 hit.
    PS50013. CHROMO_2. 1 hit.
    PS50868. POST_SET. 1 hit.
    PS50867. PRE_SET. 1 hit.
    PS51579. SAM_MT43_SUVAR39_3. 1 hit.
    PS50280. SET. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    « Hide 'large scale' publications
    1. "Sus scrofa suppressor of variegation 3-9 homolog 2 (Drosophila)."
      Jiang S., Peng J.
      Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
    2. "Cloning, characterization and prokaryotic expression of porcine suppressor of variegation 3-9 homolog 2 (Suv39h2) gene."
      Liu L., Jiang S.
      Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
    3. Porcine genome sequencing project
      Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    4. Ensembl
      Submitted (MAY-2011) to UniProtKB
      Cited for: IDENTIFICATION.
    5. Ensembl
      Submitted (MAY-2012) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiQ27I49_PIG
    AccessioniPrimary (citable) accession number: Q27I49
    Secondary accession number(s): F1RW84
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 4, 2006
    Last sequence update: April 4, 2006
    Last modified: June 11, 2014
    This is version 62 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    External Data

    Dasty 3

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