Q27919 (Q27919_ACAVI) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: Chitinase EMBL AAB68959.1
Organism	Acanthocheilonema viteae (Filarial nematode worm) (Dipetalonema viteae) EMBL AAB68959.1
Taxonomic identifier	6277 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Nematoda › Chromadorea › Spirurida › Filarioidea › Onchocercidae › Acanthocheilonema

Protein attributes

Sequence length	524 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the glycosyl hydrolase 18 family. RuleBase RU004453

Ontologies

Keywords
Molecular function	Glycosidase RuleBase RU000489 Hydrolase
Gene Ontology (GO)
Biological process	chitin catabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	extracellular region Inferred from electronic annotation. Source: InterPro
Molecular function	cation binding Inferred from electronic annotation. Source: InterPro chitin binding Inferred from electronic annotation. Source: InterPro chitinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q27919 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: D0FF315DEDFEFDB1	FASTA	524	58,321
	10 20 30 40 50 60 MNWIMITLFI ILANAITVVN GYVRGCYYTN WAQYRQGEGK FLPEDIPIGL CTHILYAFAK 70 80 90 100 110 120 VDEKGTSMAF EWNDEDTEWS KGMYSRVIKL RENDPTLKIL LSYGGYNFGS STFAAIAKSA 130 140 150 160 170 180 EKRKHFIQSA TTFLRKHKFD GFDLDWEYPT GVAEEHAKLV EEMKAAFVEE AKESGKQQLL 190 200 210 220 230 240 LTAAVSAGKM TIDESYNVQS LGKSLDLLFL MSYDLHGSWE KNVDLHGELR PTERETSGTG 250 260 270 280 290 300 VCNTEFAANY WAEKGMPKQK IIIGIPAYSR GWTLSNPSET AIGAEGDRPS SPSTTNPAGG 310 320 330 340 350 360 TAAYWEICKY VKEGGKETVD KKSVGAYMVK GDQWHGYDNE ETIKIKMKWL KEEDYGGAFM 370 380 390 400 410 420 WTLDFDDFKG TSCGKGPYPL LNAINNGLES EQTPSTRAVP ETTEDTEVEA MTEAPGTAND 430 440 450 460 470 480 TEMETAEMPE TTEDIEIETS TETSSTTAAP ETTEGTEVET TTSVVKPGEE CPEPDGLFPH 490 500 510 520 HSDCHLFINC ANNYPHIMEC PVGTFFDDTI KVCNYMRNAP DTCK

References

[1]	"Transmission-blocking antibodies recognize microfilarial chitinase in brugian lymphatic filariasis." Fuhrman J.A., Lane W.S., Smith R.F., Piessens W.F., Perler F.B. Proc. Natl. Acad. Sci. U.S.A. 89:1548-1552(1992) [PubMed: 1542646] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	"Chitinase genes expressed by infective larvae of the filarial nematodes, Acanthocheilonema viteae and Onchocerca volvulus." Wu Y., Adam R., Williams S.A., Bianco A.E. Mol. Biochem. Parasitol. 75:207-219(1996) [PubMed: 8992319] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L42010 mRNA. Translation: AAB68959.1.
3D structure databases
HSSP	HSSP built from PDB template 1LG2 based on UniProtKB Q13231.
ProteinModelPortal	Q27919.
ModBase	Search...
Protein family/group databases
CAZy	CBM14. Carbohydrate-Binding Module Family 14. GH18. Glycoside Hydrolase Family 18.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR002557. Chitin-bd_dom. IPR011583. Chitinase_II. IPR001223. Glyco_hydro18cat. IPR001579. Glyco_hydro_18_chit_AS. IPR013781. Glyco_hydro_subgr_catalytic. IPR017853. Glycoside_hydrolase_SF. [Graphical view]
Gene3D	G3DSA:2.170.140.10. Chitin-bd_dom. 1 hit. G3DSA:3.20.20.80. Glyco_hydro_cat. 2 hits.
Pfam	PF01607. CBM_14. 1 hit. PF00704. Glyco_hydro_18. 1 hit. [Graphical view]
SMART	SM00494. ChtBD2. 1 hit. SM00636. Glyco_18. 1 hit. [Graphical view]
SUPFAM	SSF57625. Chitin_bind_PerA. 1 hit. SSF51445. Glyco_hydro_cat. 1 hit.
PROSITE	PS50940. CHIT_BIND_II. 1 hit. PS01095. CHITINASE_18. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q27919_ACAVI

Accession

Primary (citable) accession number: Q27919

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1996
Last sequence update:	November 1, 1996
Last modified:	September 21, 2011
This is version 60 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)