Q27792 (Q27792_TOXCA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Recommended name: Superoxide dismutase [Cu-Zn] RuleBase RU000393 EC=1.15.1.1 RuleBase RU000393
Organism	Toxocara canis (Canine roundworm) EMBL AAB00227.1
Taxonomic identifier	6265 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Nematoda › Chromadorea › Ascaridida › Ascaridoidea › Toxocaridae › Toxocara

Protein attributes

Sequence length	190 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Destroys radicals which are normally produced within the cells and which are toxic to biological systems By similarity. RuleBase RU000393
Catalytic activity	2 superoxide + 2 H+ = O2 + H2O2. RuleBase RU000393
Cofactor	Binds 1 copper ion per subunit By similarity. RuleBase RU000393 Binds 1 zinc ion per subunit By similarity. RuleBase RU000393
Sequence similarities	Belongs to the Cu-Zn superoxide dismutase family. RuleBase RU000393

Ontologies

Keywords
Ligand	Copper RuleBase RU000393 Metal-binding RuleBase RU000393 Zinc RuleBase RU000393
Molecular function	Oxidoreductase RuleBase RU000393
Gene Ontology (GO)
Biological_process	superoxide metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW superoxide dismutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q27792 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 740572CAE59F0B2B	FASTA	190	20,043
	10 20 30 40 50 60 MTGLLLAFIL AIFILITYAQ RPNSHYYDSI TDRRTVTKTP AIVVLKDNGV GIRFKQDHGS 70 80 90 100 110 120 TYVNGSVKGL TPGLHGFHVH QYGDTTNGCI SAGPHFNPYN QTHGAPTDSI RHVGDLGNIR 130 140 150 160 170 180 AGADGTAHIS ISDKHIKLPG PNSIIGRSVV VHADQDDLGK GVGAKKQESL KTGNAGRRVA 190 CGIVASSGAP

References

[1]	"Superoxide dismutase from Toxocara canis." Matzilevich D.A., Tripp C., Maizels R.M. Submitted (APR-1996) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U55839 mRNA. Translation: AAB00227.1.
3D structure databases
HSSP	HSSP built from PDB template 1P1V based on UniProtKB P00441.
ProteinModelPortal	Q27792.
SMR	Q27792. Positions 55-188.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
Gene3D	2.60.40.200. 1 hit.
InterPro	IPR024134. SOD_Cu/Zn_/chaperones. IPR018152. SOD_Cu/Zn_BS. IPR001424. SOD_Cu_Zn_dom. [Graphical view]
PANTHER	PTHR10003. PTHR10003. 1 hit.
Pfam	PF00080. Sod_Cu. 1 hit. [Graphical view]
PRINTS	PR00068. CUZNDISMTASE.
SUPFAM	SSF49329. SOD_Cu_Zn. 1 hit.
PROSITE	PS00087. SOD_CU_ZN_1. 1 hit. PS00332. SOD_CU_ZN_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q27792_TOXCA

Accession

Primary (citable) accession number: Q27792

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1996
Last sequence update:	November 1, 1996
Last modified:	March 6, 2013
This is version 65 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)