Q27766 (Q27766_CTEFE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: Sodium pump alpha subunit EMBL AAB28239.1
Organism	Ctenocephalides felis (Cat flea) EMBL AAB28239.1
Taxonomic identifier	7515 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Siphonaptera › Pulicidae › Archaeopsyllinae › Ctenocephalides

Protein attributes

Sequence length	1037 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the cation transport ATPase (P-type) family. RuleBase RU000653

Ontologies

Keywords
Biological process	Ion transport SAAS SAAS006069 Transport
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix SAAS SAAS004014
Ligand	ATP-binding SAAS SAAS004014 RuleBase RU000653 Nucleotide-binding
Molecular function	Hydrolase RuleBase RU000653 SAAS SAAS004014
PTM	Phosphoprotein SAAS SAAS004014 RuleBase RU000653
Gene Ontology (GO)
Biological process	ATP biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: InterPro monovalent inorganic cation transmembrane transporter activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q27766 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: EF067B88B93E9F0C	FASTA	1,037	114,833
	10 20 30 40 50 60 MDDKHGRSDS YRVATVPTID DNLTADGQYK SRRKTPTKKQ RKEGELDDLK QELDIDFHKV 70 80 90 100 110 120 SPEELYQRFN THPENGLSHA KAKENLERDG PNALTPPKQT PEWVKFCKNL FGGFALLLWI 130 140 150 160 170 180 GAILCFVAYS IQASTVEEPA DDNLYLGIVL AAVVIVTGIF SYYQESKSSK IMESFKNMVP 190 200 210 220 230 240 QFATVLREGE KLTLRAEDLV LGDVVEVKFG SRIPADIRII ESRGFKVDKS SLTGESEPQS 250 260 270 280 290 300 RGPEFTNEKP LETKNLAFFS INAVEGTAKG VVISCGDNTV MGRIAGLASG LDTGETPIAK 310 320 330 340 350 360 EIHHFIHLIT GVAVFLGVTF FVIAIILNYH WLDAVIFLIG IIVANVPEGL LATVTVCLTL 370 380 390 400 410 420 TAKRMASKNC LVKNLEAVET LGSTSTICSD KTGTLTQNRM TVAHMWFDNQ IIEADTTEDQ 430 440 450 460 470 480 SGVVYDRTSP GFKALARIAT LCNRAEFKGG QEGVPILKKE VSGDASEAAL LKCMELALGD 490 500 510 520 530 540 VMSIRKRNKK VCEIPFNSTN KYQVSIHETE DASDPRHVMV MKGAPERILE KCSTIFIGGK 550 560 570 580 590 600 EKLLDEEMKE AFNNAYLELG GLGERVLGFC DLMLPTDKFP LGFKFDSDDP NFPIENLRFV 610 620 630 640 650 660 GLMSMIDPPR AAVPDAVAKC RSAGIKVIMV TGDHPITAKA IAKSVGIISE GNETVEDIAQ 670 680 690 700 710 720 RLNIPVSEVN PREAKAAVVH GTELRELNSD QLDEILRYHT EIVFARTSPQ QKLIIVEGCQ 730 740 750 760 770 780 RMGAIVAVTG DGVNDSPALK KADIGVAMGI AGSDVSKQAA DMILLDDNFA SIVTGVEEGR 790 800 810 820 830 840 LIFDNLKKSI AYTLTSNIPE ISPFLAFILC DIPLPLGTVT ILCIDLGTDM VPAISLAYEH 850 860 870 880 890 900 AEADIMKRPP RDPVNDKLVN SRLISMAYGQ IGMIQAAAGF FVYFVIMAEN GFLPMKLFGI 910 920 930 940 950 960 RKQWDSKAVN DLTDSYGQEW TYRDRKTLEY TCHTAFFVSI VVVQWADLIV CKTRRNSLLH 970 980 990 1000 1010 1020 QGMRNWALNF GLVFETALAA FLSYTPGMDK GLRMFPLKFV WWLPALPFMI SIFIYDETRR 1030 FYLRRNPGGW LEQETYY

References

[1]	"Cloning and sequence analysis of the alpha subunit of the cat flea sodium pump." Reeves S.A., Yamanaka M.K. Insect Biochem. Mol. Biol. 23:809-814(1993) [PubMed: 8397036] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	S66043 mRNA. Translation: AAB28239.1.
PIR	A56594.
3D structure databases
HSSP	HSSP built from PDB template 1MO7 based on UniProtKB P06685.
ProteinModelPortal	Q27766.
SMR	Q27766. Positions 41-1037.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR023306. ATPase_cation_domN. IPR008250. ATPase_P-typ_ATPase-assoc-dom. IPR005775. ATPase_P-typ_cation-ex_asu_euk. IPR006069. ATPase_P-typ_cation-exchng_asu. IPR006068. ATPase_P-typ_cation-transptr_C. IPR004014. ATPase_P-typ_cation-transptr_N. IPR023300. ATPase_P-typ_cyto_domA. IPR023299. ATPase_P-typ_cyto_domN. IPR001757. ATPase_P-typ_ion-transptr. IPR018303. ATPase_P-typ_P_site. IPR023298. ATPase_P-typ_TM_dom. IPR005834. Dehalogen-like_hydro. IPR023214. HAD-like_dom. [Graphical view]
Gene3D	G3DSA:2.70.150.10. ATPase_P-typ_cyto_domA. 1 hit. G3DSA:3.40.1110.10. ATPase_P-typ_cyto_domN. 1 hit. G3DSA:1.20.1110.10. ATPase_P-typ_TM_dom. 2 hits.
Pfam	PF00689. Cation_ATPase_C. 1 hit. PF00690. Cation_ATPase_N. 1 hit. PF00122. E1-E2_ATPase. 1 hit. PF00702. Hydrolase. 1 hit. [Graphical view]
PRINTS	PR00119. CATATPASE. PR00121. NAKATPASE.
SMART	SM00831. Cation_ATPase_N. 1 hit. [Graphical view]
SUPFAM	SSF81660. ATPase_cation_domN. 1 hit. SSF56784. HAD-like_dom. 1 hit.
TIGRFAMs	TIGR01106. ATPase-IIC_X-K. 1 hit. TIGR01494. ATPase_P-type. 2 hits.
PROSITE	PS00154. ATPASE_E1_E2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q27766_CTEFE

Accession

Primary (citable) accession number: Q27766

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1996
Last sequence update:	November 1, 1996
Last modified:	June 28, 2011
This is version 68 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)