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Protein

Sodium/potassium-transporting ATPase subunit alpha

Gene
N/A
Organism
Ctenocephalides felis (Cat flea)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

HydrolaseUniRule annotationSAAS annotation

Keywords - Biological processi

Ion transport, Potassium transportUniRule annotation, Transport

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Metal-bindingUniRule annotation, Nucleotide-binding, Potassium

Names & Taxonomyi

Protein namesi
Recommended name:
Sodium/potassium-transporting ATPase subunit alphaUniRule annotation (EC:3.6.3.-UniRule annotation)
OrganismiCtenocephalides felis (Cat flea)Imported
Taxonomic identifieri7515 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaSiphonapteraPulicidaeArchaeopsyllinaeCtenocephalides

Subcellular locationi

  • Membrane UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei110 – 13223HelicalUniRule annotationAdd
BLAST
Transmembranei144 – 16320HelicalUniRule annotationAdd
BLAST
Transmembranei305 – 32925HelicalUniRule annotationAdd
BLAST
Transmembranei335 – 35824HelicalUniRule annotationAdd
BLAST
Transmembranei867 – 88620HelicalUniRule annotationAdd
BLAST
Transmembranei928 – 94619HelicalUniRule annotationAdd
BLAST
Transmembranei966 – 98722HelicalUniRule annotationAdd
BLAST
Transmembranei999 – 101517HelicalUniRule annotationAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Structurei

3D structure databases

ProteinModelPortaliQ27766.
SMRiQ27766. Positions 41-1037.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini56 – 13075Cation_ATPase_NInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

Family and domain databases

Gene3Di1.20.1110.10. 2 hits.
2.70.150.10. 2 hits.
3.40.1110.10. 1 hit.
InterProiIPR006068. ATPase_P-typ_cation-transptr_C.
IPR004014. ATPase_P-typ_cation-transptr_N.
IPR023299. ATPase_P-typ_cyto_domN.
IPR018303. ATPase_P-typ_P_site.
IPR023298. ATPase_P-typ_TM_dom.
IPR008250. ATPase_P-typ_transduc_dom_A.
IPR023214. HAD-like_dom.
IPR005775. P-type_ATPase_IIC.
IPR001757. P_typ_ATPase.
[Graphical view]
PfamiPF00689. Cation_ATPase_C. 1 hit.
PF00690. Cation_ATPase_N. 1 hit.
PF00122. E1-E2_ATPase. 1 hit.
[Graphical view]
SMARTiSM00831. Cation_ATPase_N. 1 hit.
[Graphical view]
SUPFAMiSSF56784. SSF56784. 3 hits.
SSF81660. SSF81660. 1 hit.
TIGRFAMsiTIGR01106. ATPase-IIC_X-K. 1 hit.
TIGR01494. ATPase_P-type. 2 hits.
PROSITEiPS00154. ATPASE_E1_E2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q27766-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDDKHGRSDS YRVATVPTID DNLTADGQYK SRRKTPTKKQ RKEGELDDLK
60 70 80 90 100
QELDIDFHKV SPEELYQRFN THPENGLSHA KAKENLERDG PNALTPPKQT
110 120 130 140 150
PEWVKFCKNL FGGFALLLWI GAILCFVAYS IQASTVEEPA DDNLYLGIVL
160 170 180 190 200
AAVVIVTGIF SYYQESKSSK IMESFKNMVP QFATVLREGE KLTLRAEDLV
210 220 230 240 250
LGDVVEVKFG SRIPADIRII ESRGFKVDKS SLTGESEPQS RGPEFTNEKP
260 270 280 290 300
LETKNLAFFS INAVEGTAKG VVISCGDNTV MGRIAGLASG LDTGETPIAK
310 320 330 340 350
EIHHFIHLIT GVAVFLGVTF FVIAIILNYH WLDAVIFLIG IIVANVPEGL
360 370 380 390 400
LATVTVCLTL TAKRMASKNC LVKNLEAVET LGSTSTICSD KTGTLTQNRM
410 420 430 440 450
TVAHMWFDNQ IIEADTTEDQ SGVVYDRTSP GFKALARIAT LCNRAEFKGG
460 470 480 490 500
QEGVPILKKE VSGDASEAAL LKCMELALGD VMSIRKRNKK VCEIPFNSTN
510 520 530 540 550
KYQVSIHETE DASDPRHVMV MKGAPERILE KCSTIFIGGK EKLLDEEMKE
560 570 580 590 600
AFNNAYLELG GLGERVLGFC DLMLPTDKFP LGFKFDSDDP NFPIENLRFV
610 620 630 640 650
GLMSMIDPPR AAVPDAVAKC RSAGIKVIMV TGDHPITAKA IAKSVGIISE
660 670 680 690 700
GNETVEDIAQ RLNIPVSEVN PREAKAAVVH GTELRELNSD QLDEILRYHT
710 720 730 740 750
EIVFARTSPQ QKLIIVEGCQ RMGAIVAVTG DGVNDSPALK KADIGVAMGI
760 770 780 790 800
AGSDVSKQAA DMILLDDNFA SIVTGVEEGR LIFDNLKKSI AYTLTSNIPE
810 820 830 840 850
ISPFLAFILC DIPLPLGTVT ILCIDLGTDM VPAISLAYEH AEADIMKRPP
860 870 880 890 900
RDPVNDKLVN SRLISMAYGQ IGMIQAAAGF FVYFVIMAEN GFLPMKLFGI
910 920 930 940 950
RKQWDSKAVN DLTDSYGQEW TYRDRKTLEY TCHTAFFVSI VVVQWADLIV
960 970 980 990 1000
CKTRRNSLLH QGMRNWALNF GLVFETALAA FLSYTPGMDK GLRMFPLKFV
1010 1020 1030
WWLPALPFMI SIFIYDETRR FYLRRNPGGW LEQETYY
Length:1,037
Mass (Da):114,833
Last modified:November 1, 1996 - v1
Checksum:iEF067B88B93E9F0C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
S66043 mRNA. Translation: AAB28239.1.
PIRiA56594.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
S66043 mRNA. Translation: AAB28239.1.
PIRiA56594.

3D structure databases

ProteinModelPortaliQ27766.
SMRiQ27766. Positions 41-1037.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di1.20.1110.10. 2 hits.
2.70.150.10. 2 hits.
3.40.1110.10. 1 hit.
InterProiIPR006068. ATPase_P-typ_cation-transptr_C.
IPR004014. ATPase_P-typ_cation-transptr_N.
IPR023299. ATPase_P-typ_cyto_domN.
IPR018303. ATPase_P-typ_P_site.
IPR023298. ATPase_P-typ_TM_dom.
IPR008250. ATPase_P-typ_transduc_dom_A.
IPR023214. HAD-like_dom.
IPR005775. P-type_ATPase_IIC.
IPR001757. P_typ_ATPase.
[Graphical view]
PfamiPF00689. Cation_ATPase_C. 1 hit.
PF00690. Cation_ATPase_N. 1 hit.
PF00122. E1-E2_ATPase. 1 hit.
[Graphical view]
SMARTiSM00831. Cation_ATPase_N. 1 hit.
[Graphical view]
SUPFAMiSSF56784. SSF56784. 3 hits.
SSF81660. SSF81660. 1 hit.
TIGRFAMsiTIGR01106. ATPase-IIC_X-K. 1 hit.
TIGR01494. ATPase_P-type. 2 hits.
PROSITEiPS00154. ATPASE_E1_E2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ27766_CTEFE
AccessioniPrimary (citable) accession number: Q27766
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: July 6, 2016
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.