Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Superoxide dismutase [Fe]

Gene

SODB

Organism
Plasmodium falciparum (isolate HB3)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

Catalytic activityi

2 superoxide + 2 H+ = O2 + H2O2.1 Publication

Cofactori

Fe cationBy similarityNote: Binds 1 Fe cation per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi27IronBy similarity1
Metal bindingi74IronBy similarity1
Metal bindingi158IronBy similarity1
Metal bindingi162IronBy similarity1

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductase
LigandIron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Superoxide dismutase [Fe] (EC:1.15.1.1)
Alternative name(s):
FeSOD
Gene namesi
Name:SODB
OrganismiPlasmodium falciparum (isolate HB3)
Taxonomic identifieri137071 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Laverania)

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002901121 – 198Superoxide dismutase [Fe]Add BLAST198

Interactioni

Subunit structurei

Homodimer.1 Publication

Structurei

Secondary structure

1198
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Turni12 – 18Combined sources7
Helixi21 – 29Combined sources9
Helixi31 – 43Combined sources13
Turni47 – 50Combined sources4
Helixi53 – 59Combined sources7
Helixi62 – 79Combined sources18
Helixi92 – 101Combined sources10
Helixi104 – 117Combined sources14
Beta strandi120 – 128Combined sources9
Beta strandi134 – 140Combined sources7
Turni145 – 149Combined sources5
Beta strandi152 – 158Combined sources7
Helixi161 – 163Combined sources3
Helixi165 – 168Combined sources4
Helixi172 – 179Combined sources8
Turni180 – 182Combined sources3
Helixi185 – 196Combined sources12

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2GOJX-ray2.00A/B2-198[»]
ProteinModelPortaliQ27740
SMRiQ27740
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ27740

Family & Domainsi

Sequence similaritiesi

Family and domain databases

Gene3Di1.10.287.990, 1 hit
2.40.500.20, 1 hit
InterProiView protein in InterPro
IPR001189 Mn/Fe_SOD
IPR019833 Mn/Fe_SOD_BS
IPR019832 Mn/Fe_SOD_C
IPR019831 Mn/Fe_SOD_N
IPR036324 Mn/Fe_SOD_N_sf
IPR036314 SOD_C_sf
PfamiView protein in Pfam
PF02777 Sod_Fe_C, 1 hit
PF00081 Sod_Fe_N, 1 hit
PIRSFiPIRSF000349 SODismutase, 1 hit
PRINTSiPR01703 MNSODISMTASE
SUPFAMiSSF46609 SSF46609, 1 hit
SSF54719 SSF54719, 1 hit
PROSITEiView protein in PROSITE
PS00088 SOD_MN, 1 hit

Sequencei

Sequence statusi: Complete.

Q27740-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVITLPKLKY ALNALSPHIS EETLNFHYNK HHAGYVNKLN TLIKDTPFAE
60 70 80 90 100
KSLLDIVKES SGAIFNNAAQ IWNHTFYWDS MGPDCGGEPH GEIKEKIQED
110 120 130 140 150
FGSFNNFKEQ FSNILCGHFG SGWGWLALNN NNKLVILQTH DAGNPIKDNT
160 170 180 190
GIPILTCDIW EHAYYIDYRN DRASYVKAWW NLVNWNFANE NLKKAMKK
Length:198
Mass (Da):22,734
Last modified:November 1, 1996 - v1
Checksum:i0C768B66E6044D3B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z49819 mRNA Translation: CAA89971.1
PIRiS55499

Similar proteinsi

Entry informationi

Entry nameiSODF_PLAFX
AccessioniPrimary (citable) accession number: Q27740
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 12, 2007
Last sequence update: November 1, 1996
Last modified: March 28, 2018
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health