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Protein
Submitted name:

P-type ATPase

Gene

PfATPase4

Organism
Plasmodium falciparum
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

HydrolaseUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Protein family/group databases

TCDBi3.A.3.2.8. the p-type atpase (p-atpase) superfamily.

Names & Taxonomyi

Protein namesi
Submitted name:
P-type ATPaseImported
Gene namesi
Name:PfATPase4Imported
OrganismiPlasmodium falciparumImported
Taxonomic identifieri5833 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Laverania)

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei165 – 19127HelicalSequence analysisAdd
BLAST
Transmembranei197 – 21418HelicalSequence analysisAdd
BLAST
Transmembranei357 – 38125HelicalSequence analysisAdd
BLAST
Transmembranei393 – 41927HelicalSequence analysisAdd
BLAST
Transmembranei925 – 94824HelicalSequence analysisAdd
BLAST
Transmembranei998 – 102427HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Structurei

3D structure databases

ProteinModelPortaliQ27724.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini118 – 19376Cation_ATPase_NInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. [View classification]UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Family and domain databases

Gene3Di1.20.1110.10. 3 hits.
2.70.150.10. 2 hits.
3.40.1110.10. 2 hits.
InterProiIPR006068. ATPase_P-typ_cation-transptr_C.
IPR004014. ATPase_P-typ_cation-transptr_N.
IPR023299. ATPase_P-typ_cyto_domN.
IPR018303. ATPase_P-typ_P_site.
IPR023298. ATPase_P-typ_TM_dom.
IPR008250. ATPase_P-typ_transduc_dom_A.
IPR023214. HAD-like_dom.
IPR001757. P_typ_ATPase.
[Graphical view]
PfamiPF00689. Cation_ATPase_C. 1 hit.
PF00690. Cation_ATPase_N. 1 hit.
PF00122. E1-E2_ATPase. 1 hit.
[Graphical view]
PRINTSiPR00120. HATPASE.
SMARTiSM00831. Cation_ATPase_N. 1 hit.
[Graphical view]
SUPFAMiSSF56784. SSF56784. 2 hits.
SSF81660. SSF81660. 1 hit.
TIGRFAMsiTIGR01494. ATPase_P-type. 2 hits.
PROSITEiPS00154. ATPASE_E1_E2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q27724-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSQNNNKQG GQDINNKKDS DDIKPSVSKE DLINSLKNDE LNKNTTMDQN
60 70 80 90 100
DMKKNENMNI KKNEVLNNSN NVEDGDNENS KFMNKSKEGL NNINGEKNDD
110 120 130 140 150
NNSIVKVEES PKSIGYNYYA SESIENLCKE FGLESINTGL NSEQVKINRD
160 170 180 190 200
KYGENFIEKD EVVPVWLIFL SQYCSPVVLL LLVAAVASLA LNEVVEGVAI
210 220 230 240 250
ISIVTLNACL ATYMEKSSGD AIGKLAEMAS PQCTVLRNGQ KVVIPSREVV
260 270 280 290 300
VGDVVLINTG DSISADLRLF DVIELKTNES LLTGESEDIK KTIVADNLST
310 320 330 340 350
PFATNLCFAT TSVTSGSGKG IVISTGLDTQ VGKIASQLKK SSKGSKLTPL
360 370 380 390 400
QVALNKLGGL IGLIAIIVLV VIISLAVIIK YRDPAHADKD PTFVIIIIGV
410 420 430 440 450
GFAVSSIPEG LPMVVTITLS AGAKDMVKKN ANVRKLPAVE TLGCCSVICS
460 470 480 490 500
DKTGTLTEGK MTAINAVTIC KNSSLSDENN KLTKTFDFYP TKGFEPCGGL
510 520 530 540 550
FDSNELTSEK KKEIVIAKNQ NTSYDKVLYN YGNPSNKSVI VDKTRSLMFA
560 570 580 590 600
AYLNSYDTTL SRDPKTLKWG IHGNMSEGPI VVAAAKVGYS FINNPNHKSY
610 620 630 640 650
LDNFQRLDDL EVTFNSSRKM KITFYKLKTV NVFENVYLDK PRKEYTHIAL
660 670 680 690 700
IKGAPDRLLD RSTHLLEETS MKKVQVSWNS TITQEERNVL IKKNLELSQK
710 720 730 740 750
ALRVLSICIK PLTDQNIEEL KKLEDADADE RLKYVNYDEN GGFIPMGYVA
760 770 780 790 800
SFDPPRPGVK EAIQTCREAQ VKVIMITGDQ KPTAVAIGKL IGLIEEKSEQ
810 820 830 840 850
VEDINSLAIE CSELHINKNP NEPILPNDQL DEFTDKILIY SRAQQEDKIT
860 870 880 890 900
IVQSLKRKGY LVAMTGDGVN DAPALKAADI GVAMGINGTE VAKGASEMIL
910 920 930 940 950
IDDNFCTVVS AIDVGRTIFS NIQKFVCFLL GTNIGEIIYL SVAIVAQMPF
960 970 980 990 1000
PLEALQILFL NLMTDGCPAV ALSREPPNDD NMKTPPRPKK QPIMTKRWWF
1010 1020 1030 1040 1050
YGILPHTIFE ALCVLLSLAF SLYICTGFYN LNGIHNLCKT VNLVDVNDAN
1060 1070 1080 1090 1100
VYHEYKYFCS SYEYRISTDY VGWVTNVSFW DPQNNEAVNF WGAAKGKVEN
1110 1120 1130 1140 1150
INPLSDIVHP ELRLRMQDGC SGDLTLDENR WCRPKDNKTS DGYNDELEGI
1160 1170 1180 1190 1200
LKKGFEDVTA KGSKRGRTMA FISAVWCEML RAYTVRRREP FYKVFNRNMW
1210 1220
MHLACSISAT LTFLSTCIPG ITSILNTT
Length:1,228
Mass (Da):135,990
Last modified:November 1, 1996 - v1
Checksum:i32C3CFD324964CBE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U39298 mRNA. Translation: AAC47167.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U39298 mRNA. Translation: AAC47167.1.

3D structure databases

ProteinModelPortaliQ27724.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

TCDBi3.A.3.2.8. the p-type atpase (p-atpase) superfamily.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di1.20.1110.10. 3 hits.
2.70.150.10. 2 hits.
3.40.1110.10. 2 hits.
InterProiIPR006068. ATPase_P-typ_cation-transptr_C.
IPR004014. ATPase_P-typ_cation-transptr_N.
IPR023299. ATPase_P-typ_cyto_domN.
IPR018303. ATPase_P-typ_P_site.
IPR023298. ATPase_P-typ_TM_dom.
IPR008250. ATPase_P-typ_transduc_dom_A.
IPR023214. HAD-like_dom.
IPR001757. P_typ_ATPase.
[Graphical view]
PfamiPF00689. Cation_ATPase_C. 1 hit.
PF00690. Cation_ATPase_N. 1 hit.
PF00122. E1-E2_ATPase. 1 hit.
[Graphical view]
PRINTSiPR00120. HATPASE.
SMARTiSM00831. Cation_ATPase_N. 1 hit.
[Graphical view]
SUPFAMiSSF56784. SSF56784. 2 hits.
SSF81660. SSF81660. 1 hit.
TIGRFAMsiTIGR01494. ATPase_P-type. 2 hits.
PROSITEiPS00154. ATPASE_E1_E2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Analysis of a cation-transporting ATPase of Plasmodium falciparum."
    Dyer M., Jackson M., McWhinney C., Zhao G., Mikkelsen R.
    Mol. Biochem. Parasitol. 78:1-12(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: K1Imported.

Entry informationi

Entry nameiQ27724_PLAFA
AccessioniPrimary (citable) accession number: Q27724
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: May 11, 2016
This is version 105 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.