Q27724 (Q27724_PLAFA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
P-type ATPase EMBL AAC47167.1

Gene names

Name:

PfATPase4 EMBL AAC47167.1

Organism

Plasmodium falciparum EMBL AAC47167.1

Taxonomic identifier

5833 [NCBI]

Taxonomic lineage

Eukaryota › Alveolata › Apicomplexa › Aconoidasida › Haemosporida › Plasmodium › Plasmodium (Laverania)

Protein attributes

Sequence length	1228 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the cation transport ATPase (P-type) family. RuleBase RU000653

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix SAAS SAAS004014
Ligand	ATP-binding SAAS SAAS004014 RuleBase RU000653 Nucleotide-binding
Molecular function	Hydrolase SAAS SAAS004014 RuleBase RU000653
PTM	Phosphoprotein SAAS SAAS004014 RuleBase RU000653
Gene Ontology (GO)
Biological process	cation transport Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q27724 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 32C3CFD324964CBE	FASTA	1,228	135,990
	10 20 30 40 50 60 MSSQNNNKQG GQDINNKKDS DDIKPSVSKE DLINSLKNDE LNKNTTMDQN DMKKNENMNI 70 80 90 100 110 120 KKNEVLNNSN NVEDGDNENS KFMNKSKEGL NNINGEKNDD NNSIVKVEES PKSIGYNYYA 130 140 150 160 170 180 SESIENLCKE FGLESINTGL NSEQVKINRD KYGENFIEKD EVVPVWLIFL SQYCSPVVLL 190 200 210 220 230 240 LLVAAVASLA LNEVVEGVAI ISIVTLNACL ATYMEKSSGD AIGKLAEMAS PQCTVLRNGQ 250 260 270 280 290 300 KVVIPSREVV VGDVVLINTG DSISADLRLF DVIELKTNES LLTGESEDIK KTIVADNLST 310 320 330 340 350 360 PFATNLCFAT TSVTSGSGKG IVISTGLDTQ VGKIASQLKK SSKGSKLTPL QVALNKLGGL 370 380 390 400 410 420 IGLIAIIVLV VIISLAVIIK YRDPAHADKD PTFVIIIIGV GFAVSSIPEG LPMVVTITLS 430 440 450 460 470 480 AGAKDMVKKN ANVRKLPAVE TLGCCSVICS DKTGTLTEGK MTAINAVTIC KNSSLSDENN 490 500 510 520 530 540 KLTKTFDFYP TKGFEPCGGL FDSNELTSEK KKEIVIAKNQ NTSYDKVLYN YGNPSNKSVI 550 560 570 580 590 600 VDKTRSLMFA AYLNSYDTTL SRDPKTLKWG IHGNMSEGPI VVAAAKVGYS FINNPNHKSY 610 620 630 640 650 660 LDNFQRLDDL EVTFNSSRKM KITFYKLKTV NVFENVYLDK PRKEYTHIAL IKGAPDRLLD 670 680 690 700 710 720 RSTHLLEETS MKKVQVSWNS TITQEERNVL IKKNLELSQK ALRVLSICIK PLTDQNIEEL 730 740 750 760 770 780 KKLEDADADE RLKYVNYDEN GGFIPMGYVA SFDPPRPGVK EAIQTCREAQ VKVIMITGDQ 790 800 810 820 830 840 KPTAVAIGKL IGLIEEKSEQ VEDINSLAIE CSELHINKNP NEPILPNDQL DEFTDKILIY 850 860 870 880 890 900 SRAQQEDKIT IVQSLKRKGY LVAMTGDGVN DAPALKAADI GVAMGINGTE VAKGASEMIL 910 920 930 940 950 960 IDDNFCTVVS AIDVGRTIFS NIQKFVCFLL GTNIGEIIYL SVAIVAQMPF PLEALQILFL 970 980 990 1000 1010 1020 NLMTDGCPAV ALSREPPNDD NMKTPPRPKK QPIMTKRWWF YGILPHTIFE ALCVLLSLAF 1030 1040 1050 1060 1070 1080 SLYICTGFYN LNGIHNLCKT VNLVDVNDAN VYHEYKYFCS SYEYRISTDY VGWVTNVSFW 1090 1100 1110 1120 1130 1140 DPQNNEAVNF WGAAKGKVEN INPLSDIVHP ELRLRMQDGC SGDLTLDENR WCRPKDNKTS 1150 1160 1170 1180 1190 1200 DGYNDELEGI LKKGFEDVTA KGSKRGRTMA FISAVWCEML RAYTVRRREP FYKVFNRNMW 1210 1220 MHLACSISAT LTFLSTCIPG ITSILNTT

References

[1]	"Analysis of a cation-transporting ATPase of Plasmodium falciparum." Dyer M., Jackson M., McWhinney C., Zhao G., Mikkelsen R. Mol. Biochem. Parasitol. 78:1-12(1996) [PubMed: 8813672] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: K1 EMBL AAC47167.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U39298 mRNA. Translation: AAC47167.1.
3D structure databases
HSSP	HSSP built from PDB template 1SU4 based on UniProtKB P04191.
ProteinModelPortal	Q27724.
ModBase	Search...
Protein family/group databases
TCDB	3.A.3.2.8. P-type ATPase (P-ATPase) superfamily.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR023306. ATPase_cation_domN. IPR008250. ATPase_P-typ_ATPase-assoc-dom. IPR006068. ATPase_P-typ_cation-transptr_C. IPR004014. ATPase_P-typ_cation-transptr_N. IPR023300. ATPase_P-typ_cyto_domA. IPR023299. ATPase_P-typ_cyto_domN. IPR000695. ATPase_P-typ_H-transp. IPR001757. ATPase_P-typ_ion-transptr. IPR018303. ATPase_P-typ_P_site. IPR023298. ATPase_P-typ_TM_dom. IPR005834. Dehalogen-like_hydro. IPR023214. HAD-like_dom. [Graphical view]
Gene3D	G3DSA:2.70.150.10. ATPase_P-typ_cyto_domA. 2 hits. G3DSA:3.40.1110.10. ATPase_P-typ_cyto_domN. 2 hits. G3DSA:1.20.1110.10. ATPase_P-typ_TM_dom. 3 hits.
Pfam	PF00689. Cation_ATPase_C. 1 hit. PF00690. Cation_ATPase_N. 1 hit. PF00122. E1-E2_ATPase. 1 hit. PF00702. Hydrolase. 1 hit. [Graphical view]
PRINTS	PR00119. CATATPASE. PR00120. HATPASE.
SMART	SM00831. Cation_ATPase_N. 1 hit. [Graphical view]
SUPFAM	SSF81660. ATPase_cation_domN. 1 hit. SSF56784. HAD-like_dom. 1 hit.
TIGRFAMs	TIGR01494. ATPase_P-type. 2 hits.
PROSITE	PS00154. ATPASE_E1_E2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q27724_PLAFA

Accession

Primary (citable) accession number: Q27724

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1996
Last sequence update:	November 1, 1996
Last modified:	December 14, 2011
This is version 77 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)