Q27720 (Q27720_PLAFA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: ATPase 2 EMBL AAA67064.1
Organism	Plasmodium falciparum EMBL AAA67064.1
Taxonomic identifier	5833 [NCBI]
Taxonomic lineage	Eukaryota › Alveolata › Apicomplexa › Aconoidasida › Haemosporida › Plasmodium › Plasmodium (Laverania)

Protein attributes

Sequence length	1501 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Catalytic activity

ATP + H2O + phospholipid(In) = ADP + phosphate + phospholipid(Out). SAAS SAAS023299

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix SAAS SAAS023306
Ligand	ATP-binding SAAS SAAS023306 Magnesium SAAS SAAS023299 Nucleotide-binding
Molecular function	Hydrolase SAAS SAAS023299
Gene Ontology (GO)
Biological process	cation transport Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism Inferred from electronic annotation. Source: InterPro magnesium ion binding Inferred from electronic annotation. Source: InterPro phospholipid-translocating ATPase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q27720 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 809451D6DB42168D	FASTA	1,501	172,849
	10 20 30 40 50 60 MYEQFHKISN VYFFFIGILQ VIPQFTATNG IPTVFFPLLI VLTANAIKDA FEDWNRHKTD 70 80 90 100 110 120 KIENNRMCYG IVSEEEKKIY QEKSNKKNIF KKLKRYFFGN RKICNTENYY DEDDMCDDEI 130 140 150 160 170 180 TDINDYINNY EDNLENIEGT VKKRWKDIKA GDIILCRRSE FFCADILLLC TSHKNGIAFV 190 200 210 220 230 240 ETSSLDGETN LKVKEANTFL FNILGNDRNS AIDNVKNLKG FILSDKPNKD LSTMYGTIYF 250 260 270 280 290 300 EKDKKIDVEN IGIQELLKKT TEEIEYRKKR LSSVDLSKSS SAIGSNLCNN NNKSDSKSDI 310 320 330 340 350 360 KNYNKDDDDF DDMDENNILK NDNYIRIPFD EKQFVLRGCK LKNTDWIMGI VIYVGRETKI 370 380 390 400 410 420 QMNSSKSIKK TSKLEILTNK MTIIIWVIQM IICLISAYYN AIIVSSSRKN RFRYLPFNLE 430 440 450 460 470 480 KAKKPYIVGI ISFFSWVVIT GNFVPISLIV TMSFVKVVQA YFISCDKNMI HKVQADVPSF 490 500 510 520 530 540 GEQKEIPNIP KDDISSDADV IKRMRTKKIA DSSLLHIDEN QTEEDNMDMK SDCIAFKNNS 550 560 570 580 590 600 SHQNINGNNK QYSSSSLGII SNAPKREISS RVISFKDSKE KNYIYFNAVP RTSSLIEELG 610 620 630 640 650 660 QIEYIFSDKT GTLTCNIMEF RKCAINGISY GKGLTEIKRN ILKKKNLEIP VEPTMKFKKK 670 680 690 700 710 720 TPHVNIIDND IINHLKDPNH FNHVNLINFF LHLAINHAVI CEKDKEGVTT YSSSSPDEEA 730 740 750 760 770 780 LVNAAKHFDI TFLYRREGKY GISIFGKIYE IDTLATIEFT SKRKMSSVIC RIPVINPDYN 790 800 810 820 830 840 HPTDAKSSNM DKKKNNMDDH LVVGKNEEKE ETDDLNVYPP KKEAHSKLNN NNNNNNNIRI 850 860 870 880 890 900 DNLYDDKNNF NIIYNHNEGR TPEVITCKNS KNSKIMLFCK GAGSIILKKL AKRTDIDEIT 910 920 930 940 950 960 IEHMETYADE GLRTLCIAQR ELSEESFAEW YHLYKEASLS IKDREEKLES VAEYIENDLI 970 980 990 1000 1010 1020 LQGITGIEDK LQEGVSSTIE DLRMAGIHIW MLTGDKIETA MNIGIAANLI DNYSEQFIYT 1030 1040 1050 1060 1070 1080 EEYIESEEAL IKKIDDDILM VEKSLNIPHY NFDDENNNVE DEKRKTFFRN NFIKNFFCAK 1090 1100 1110 1120 1130 1140 NKSGLLLNPD KYNMLINTLN YVLVVDGSVI DLLLSEKMER KFFYLADKCS SVICGRVSPY 1150 1160 1170 1180 1190 1200 QKGAIVSSAN RLLNKITLAI GDGANDRNMI NTANIGIGIR GQEGVQAFNS SDYGISQFRF 1210 1220 1230 1240 1250 1260 LKNLLLVHGR LSYRRISKLV VYMFYKNMVL IFPLFIFGSI SLYSGQKIYF EFLLHLFNVL 1270 1280 1290 1300 1310 1320 FTAIPVVIHA VLDQDISLNT AMEKPNLYKL GIHHYYFNIR TFISWVMNSL FHGSVVFLIP 1330 1340 1350 1360 1370 1380 LYFLSYYNIP TSDGIPYDIW TVGCATYFLT VLIVNFKILF ETYYLNILPI SGIALSIFSF 1390 1400 1410 1420 1430 1440 VLLVTAFSFM CVGSIHLLGT IVYLVQSLRF WLVVILGLFT ALLRDYVFKV YKRNFNPEIY 1450 1460 1470 1480 1490 1500 HLLLDQENAK IGMNDVIDQL KLNEFDKDDD IRIEKSKSLG YAFSEADPAC IQLIRKQDNM I

References

[1]	"Molecular cloning and sequence of two novel P-type adenosinetriphosphatases from Plasmodium falciparum." Trottein F., Cowman A.F. Eur. J. Biochem. 227:214-225(1995) [PubMed: 7851389] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U16955 Genomic DNA. Translation: AAA67064.1.
3D structure databases
ProteinModelPortal	Q27720.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
eggNOG	KOG0206.
Family and domain databases
InterPro	IPR023306. ATPase_cation_domN. IPR008250. ATPase_P-typ_ATPase-assoc-dom. IPR023300. ATPase_P-typ_cyto_domA. IPR023299. ATPase_P-typ_cyto_domN. IPR001757. ATPase_P-typ_ion-transptr. IPR018303. ATPase_P-typ_P_site. IPR006539. ATPase_P-typ_Plipid-transl. IPR023214. HAD-like_dom. [Graphical view]
Gene3D	G3DSA:2.70.150.10. ATPase_P-typ_cyto_domA. 3 hits. G3DSA:3.40.1110.10. ATPase_P-typ_cyto_domN. 3 hits. G3DSA:3.40.50.1000. HAD-like_dom. 3 hits.
Pfam	PF00122. E1-E2_ATPase. 2 hits. [Graphical view]
SUPFAM	SSF81660. ATPase_cation_domN. 1 hit. SSF56784. HAD-like_dom. 1 hit.
TIGRFAMs	TIGR01652. ATPase-Plipid. 1 hit. TIGR01494. ATPase_P-type. 1 hit.
PROSITE	PS00154. ATPASE_E1_E2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q27720_PLAFA

Accession

Primary (citable) accession number: Q27720

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1996
Last sequence update:	November 1, 1996
Last modified:	December 14, 2011
This is version 58 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)