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Q27710 (CATA_ONCVE) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 60. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Catalase
EC=1.11.1.6
Gene names
Name:cat
OrganismOnchocerca volvulus endobacterium
Taxonomic identifier77551 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Anaplasmataceae › Wolbachieae › Wolbachia

Protein attributes

Sequence length482 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.

Catalytic activity

2 H2O2 = O2 + 2 H2O.

Cofactor

Heme group.

Sequence similarities

Belongs to the catalase family.

Ontologies

Keywords
   Biological processHydrogen peroxide
   LigandHeme
Iron
Metal-binding
   Molecular functionOxidoreductase
Peroxidase
Gene Ontology (GO)
   Biological processhydrogen peroxide catabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functioncatalase activity

Inferred from electronic annotation. Source: EC

heme binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 482482Catalase
PRO_0000084993

Sites

Active site551 By similarity
Active site1281 By similarity
Metal binding3381Iron (heme axial ligand) By similarity

Sequences

Sequence LengthMass (Da)Tools
Q27710 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: B1DA5F49BA39F776

FASTA48253,700
        10         20         30         40         50         60 
MSQNKTLTTA SGPPVADNQN SRSAGPRGPL LLDDFHLIEK LAHFNRENIP ERRVHAKGSG 

        70         80         90        100        110        120 
AYGTFTVTQD ITQYTSAKLF DSVGKQTPTF LRFSTVGGER GSADTERDPR GFALKFYTEE 

       130        140        150        160        170        180 
GNWDIVGNNT PVFFIRDPLK FPDFIHTQKR LPQSNLKSAQ MMWDFWSHSP EALHQVTILF 

       190        200        210        220        230        240 
SDRGIPDGYR HMHGFGSHTY SLINAKGERH WVKWHYKTKQ GIKNLAPADA ARLAGTDPDY 

       250        260        270        280        290        300 
AQRDLFGAIE RGDFPKWRVC IQIMTEAQAN AHYENPFDVT KTWSQKEFPL IEVGELELNR 

       310        320        330        340        350        360 
NPLNYFAEVE QAAFGPSNMV PGVGLSPDRM LQGRVFAYAD AHRYRVGTNH QQLPVNAPRS 

       370        380        390        400        410        420 
PVNSYQRDGS MAFGSNGGAA PNYEPNSYAD APKQAPQYAE PALALSGAAD RYDHREDTDY 

       430        440        450        460        470        480 
YSHAGALFRL MNDEQKALLI NNIAGAMAGV SSDVVQRQLQ YFFKADPAYG EGIASALGVS 


LN

« Hide

References

[1]Henkle-Duehrsen K.J.
Submitted (OCT-1994) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"Gene structure, activity and localization of a catalase from intracellular bacteria in Onchocerca volvulus."
Henkle-Duehrsen K.J., Eckelt V.H.O., Wildenburg G., Blaxter M.L., Walter R.D.
Submitted (MAY-1998) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		X82176 mRNA. Translation: CAA57666.1.
AF069070 Genomic DNA. Translation: AAC79431.1.
PIRS49465.

3D structure databases

ProteinModelPortalQ27710.
SMRQ27710. Positions 4-482.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR018028. Catalase.
IPR020835. Catalase-like_dom.
IPR024708. Catalase_AS.
IPR024711. Catalase_clade1/3.
IPR011614. Catalase_core.
IPR002226. Catalase_haem_BS.
IPR010582. Catalase_immune_responsive.
[Graphical view]
Gene3DG3DSA:2.40.180.10. Catalase_N. 1 hit.
PANTHERPTHR11465. Catalase. 1 hit.
PfamPF00199. Catalase. 1 hit.
PF06628. Catalase-rel. 1 hit.
[Graphical view]
PIRSFPIRSF038928. Catalase_clade1-3. 1 hit.
PRINTSPR00067. CATALASE.
SMARTSM01060. Catalase. 1 hit.
[Graphical view]
SUPFAMSSF56634. Catalase_N. 1 hit.
PROSITEPS00437. CATALASE_1. 1 hit.
PS00438. CATALASE_2. 1 hit.
PS51402. CATALASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCATA_ONCVE
AccessionPrimary (citable) accession number: Q27710
Secondary accession number(s): O85499
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: November 1, 1996
Last modified: January 25, 2012
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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