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Q27648

- Q27648_ENTHI

UniProt

Q27648 - Q27648_ENTHI

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Protein
Submitted name:

Hexokinase

Gene

HXK2

Organism
Entamoeba histolytica
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. hexokinase activity Source: UniProtKB-EC

GO - Biological processi

  1. glycolytic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseSAAS annotationImported, Transferase

Keywords - Biological processi

GlycolysisSAAS annotation

Keywords - Ligandi

ATP-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

SABIO-RKQ27648.

Names & Taxonomyi

Protein namesi
Submitted name:
HexokinaseImported (EC:2.7.1.1Imported)
Submitted name:
Hexokinase 2Imported
Gene namesi
Name:HXK2Imported
ORF Names:EHI_098560Imported
OrganismiEntamoeba histolyticaImported
Taxonomic identifieri5759 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaArchamoebaeEntamoebidaeEntamoeba
ProteomesiUP000001926: Partially assembled WGS sequence

Organism-specific databases

EuPathDBiAmoebaDB:EHI_098560.

Interactioni

Protein-protein interaction databases

STRINGi294381.C4LXD6.

Structurei

3D structure databases

ProteinModelPortaliQ27648.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotation

Phylogenomic databases

InParanoidiQ27648.
KOiK00844.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.

Sequencei

Sequence statusi: Complete.

Q27648-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MQEIIDQFAI DKEKLEIIVQ RMSEELTNGL QDKPSTLKML PSYAPIPTGK
60 70 80 90 100
EVGTFMGIDV GGTNLRVLLL EIPEPGVRGE LKSVECIMPK TSTTVDQFFG
110 120 130 140 150
FIAQKIKEFV ENNNLKEKEI KAGLTFSFAV EQIAIDKGIQ QSWSKGWDVK
160 170 180 190 200
ESIGKDIVEI FHNQLAKINV NNIRIVAFIN DTVGTFANLA YDDASCGMGL
210 220 230 240 250
IFGTGTNGCY IEKTSNFAAS KLKSVCKEDY MIVNTEWGAL DIPELGYNKF
260 270 280 290 300
DKMIDDVSIN KGEHYFEKMI SGIYMGWLAR LAIRELIEKK VIFERYADAE
310 320 330 340 350
VFSGSPDDTD CDHSKKYTSR NTGIVEDTTP ELILVDEMLK SLGVNDSTLE
360 370 380 390 400
ERKMLKAITE AVVKRAAYLA AAATVCLYRK MVPYMKERTT AGVDGSVFEK
410 420 430 440
SVPFKRFYLE ALDLLQPVEK VTCQLSKDGS GLGAVIVAAA VACKQ
Length:445
Mass (Da):49,420
Last modified:November 1, 1996 - v1
Checksum:iEA230E13F00CCABF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK419612 mRNA. Translation: BAN38277.1.
X82198 mRNA. Translation: CAA57682.1.
DS571169 Genomic DNA. Translation: EAL50580.1.
RefSeqiXP_655965.1. XM_650873.1.

Genome annotation databases

EnsemblProtistsirna_EHI_098560-1; rna_EHI_098560-1; EHI_098560.
GeneIDi3410328.
KEGGiehi:EHI_098560.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK419612 mRNA. Translation: BAN38277.1 .
X82198 mRNA. Translation: CAA57682.1 .
DS571169 Genomic DNA. Translation: EAL50580.1 .
RefSeqi XP_655965.1. XM_650873.1.

3D structure databases

ProteinModelPortali Q27648.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 294381.C4LXD6.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblProtistsi rna_EHI_098560-1 ; rna_EHI_098560-1 ; EHI_098560 .
GeneIDi 3410328.
KEGGi ehi:EHI_098560.

Organism-specific databases

EuPathDBi AmoebaDB:EHI_098560.

Phylogenomic databases

InParanoidi Q27648.
KOi K00844.

Enzyme and pathway databases

SABIO-RK Q27648.

Family and domain databases

InterProi IPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view ]
PANTHERi PTHR19443. PTHR19443. 1 hit.
Pfami PF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view ]
PRINTSi PR00475. HEXOKINASE.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Molecular analysis of two hexokinase isoenzymes, pathogencity markers for the human parasite Entamoeba histolytica."
    Ortner S., Plaimauer B., Binder M., Scheiner O., Wiedermann G., Duchene M.
    Mol. Biochem. Parasitol. 73:189-198(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: SFL-3Imported.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 30459 / HM-1:IMSSImported.
  3. Lorenzi H., Amedeo P., Inman J., Schobel S., Caler E.
    Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: ATCC 30459 / HM-1:IMSSImported.
  4. "Short 5' UTR of Entamoeba genes."
    Hiranuka K., Kumagai M., Wakaguri H., Suzuki Y., Sugano S., Watanabe J., Makioka A.
    Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: HM-1:IMSSImported.

Entry informationi

Entry nameiQ27648_ENTHI
AccessioniPrimary (citable) accession number: Q27648
Secondary accession number(s): C4LXD6
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: November 26, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3