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Q27648

- Q27648_ENTHI

UniProt

Q27648 - Q27648_ENTHI

Protein
Submitted name:

Hexokinase

Gene

HXK2

Organism
Entamoeba histolytica
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 66 (01 Oct 2014)
      Sequence version 1 (01 Nov 1996)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. hexokinase activity Source: UniProtKB-EC

    GO - Biological processi

    1. glycolytic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    KinaseSAAS annotationImported, Transferase

    Keywords - Biological processi

    GlycolysisSAAS annotation

    Keywords - Ligandi

    ATP-bindingSAAS annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    HexokinaseImported (EC:2.7.1.1Imported)
    Submitted name:
    Hexokinase 2Imported
    Gene namesi
    Name:HXK2Imported
    ORF Names:EHI_098560Imported
    OrganismiEntamoeba histolyticaImported
    Taxonomic identifieri5759 [NCBI]
    Taxonomic lineageiEukaryotaAmoebozoaArchamoebaeEntamoebidaeEntamoeba
    ProteomesiUP000001926: Partially assembled WGS sequence

    Organism-specific databases

    EuPathDBiAmoebaDB:EHI_098560.

    Interactioni

    Protein-protein interaction databases

    STRINGi294381.C4LXD6.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the hexokinase family.UniRule annotation

    Phylogenomic databases

    KOiK00844.

    Family and domain databases

    InterProiIPR001312. Hexokinase.
    IPR022673. Hexokinase_C.
    IPR022672. Hexokinase_N.
    [Graphical view]
    PANTHERiPTHR19443. PTHR19443. 1 hit.
    PfamiPF00349. Hexokinase_1. 1 hit.
    PF03727. Hexokinase_2. 1 hit.
    [Graphical view]
    PRINTSiPR00475. HEXOKINASE.

    Sequencei

    Sequence statusi: Complete.

    Q27648-1 [UniParc]FASTAAdd to Basket

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    MQEIIDQFAI DKEKLEIIVQ RMSEELTNGL QDKPSTLKML PSYAPIPTGK    50
    EVGTFMGIDV GGTNLRVLLL EIPEPGVRGE LKSVECIMPK TSTTVDQFFG 100
    FIAQKIKEFV ENNNLKEKEI KAGLTFSFAV EQIAIDKGIQ QSWSKGWDVK 150
    ESIGKDIVEI FHNQLAKINV NNIRIVAFIN DTVGTFANLA YDDASCGMGL 200
    IFGTGTNGCY IEKTSNFAAS KLKSVCKEDY MIVNTEWGAL DIPELGYNKF 250
    DKMIDDVSIN KGEHYFEKMI SGIYMGWLAR LAIRELIEKK VIFERYADAE 300
    VFSGSPDDTD CDHSKKYTSR NTGIVEDTTP ELILVDEMLK SLGVNDSTLE 350
    ERKMLKAITE AVVKRAAYLA AAATVCLYRK MVPYMKERTT AGVDGSVFEK 400
    SVPFKRFYLE ALDLLQPVEK VTCQLSKDGS GLGAVIVAAA VACKQ 445
    Length:445
    Mass (Da):49,420
    Last modified:November 1, 1996 - v1
    Checksum:iEA230E13F00CCABF
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK419612 mRNA. Translation: BAN38277.1.
    X82198 mRNA. Translation: CAA57682.1.
    DS571169 Genomic DNA. Translation: EAL50580.1.
    RefSeqiXP_655965.1. XM_650873.1.

    Genome annotation databases

    EnsemblProtistsirna_EHI_098560-1; rna_EHI_098560-1; EHI_098560.
    GeneIDi3410328.
    KEGGiehi:EHI_098560.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK419612 mRNA. Translation: BAN38277.1 .
    X82198 mRNA. Translation: CAA57682.1 .
    DS571169 Genomic DNA. Translation: EAL50580.1 .
    RefSeqi XP_655965.1. XM_650873.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 294381.C4LXD6.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblProtistsi rna_EHI_098560-1 ; rna_EHI_098560-1 ; EHI_098560 .
    GeneIDi 3410328.
    KEGGi ehi:EHI_098560.

    Organism-specific databases

    EuPathDBi AmoebaDB:EHI_098560.

    Phylogenomic databases

    KOi K00844.

    Family and domain databases

    InterProi IPR001312. Hexokinase.
    IPR022673. Hexokinase_C.
    IPR022672. Hexokinase_N.
    [Graphical view ]
    PANTHERi PTHR19443. PTHR19443. 1 hit.
    Pfami PF00349. Hexokinase_1. 1 hit.
    PF03727. Hexokinase_2. 1 hit.
    [Graphical view ]
    PRINTSi PR00475. HEXOKINASE.
    ProtoNeti Search...

    Publicationsi

    1. "Molecular analysis of two hexokinase isoenzymes, pathogencity markers for the human parasite Entamoeba histolytica."
      Ortner S., Plaimauer B., Binder M., Scheiner O., Wiedermann G., Duchene M.
      Mol. Biochem. Parasitol. 73:189-198(1995) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: SFL-3Imported.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 30459 / HM-1:IMSSImported.
    3. Lorenzi H., Amedeo P., Inman J., Schobel S., Caler E.
      Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases
      Cited for: GENOME REANNOTATION.
      Strain: ATCC 30459 / HM-1:IMSSImported.
    4. "Short 5' UTR of Entamoeba genes."
      Hiranuka K., Kumagai M., Wakaguri H., Suzuki Y., Sugano S., Watanabe J., Makioka A.
      Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: HM-1:IMSSImported.

    Entry informationi

    Entry nameiQ27648_ENTHI
    AccessioniPrimary (citable) accession number: Q27648
    Secondary accession number(s): C4LXD6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 1, 1996
    Last sequence update: November 1, 1996
    Last modified: October 1, 2014
    This is version 66 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3