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Protein

Phosphotransferase

Gene

HXK2

Organism
Entamoeba histolytica
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotationImported, Transferase

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
PhosphotransferaseUniRule annotation (EC:2.7.1.-UniRule annotation)
Gene namesi
Name:HXK2Imported
ORF Names:EHI_098560Imported
OrganismiEntamoeba histolyticaImported
Taxonomic identifieri5759 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaArchamoebaeEntamoebidaeEntamoeba
Proteomesi
  • UP000001926 Componenti: Partially assembled WGS sequence

Organism-specific databases

EuPathDBiAmoebaDB:EHI_098560.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi5759.rna_EHI_098560-1.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini2 – 191190Hexokinase_1InterPro annotationAdd
BLAST
Domaini198 – 439242Hexokinase_2InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG1369. Eukaryota.
COG5026. LUCA.
KOiK00844.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PROSITEiPS51748. HEXOKINASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q27648-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQEIIDQFAI DKEKLEIIVQ RMSEELTNGL QDKPSTLKML PSYAPIPTGK
60 70 80 90 100
EVGTFMGIDV GGTNLRVLLL EIPEPGVRGE LKSVECIMPK TSTTVDQFFG
110 120 130 140 150
FIAQKIKEFV ENNNLKEKEI KAGLTFSFAV EQIAIDKGIQ QSWSKGWDVK
160 170 180 190 200
ESIGKDIVEI FHNQLAKINV NNIRIVAFIN DTVGTFANLA YDDASCGMGL
210 220 230 240 250
IFGTGTNGCY IEKTSNFAAS KLKSVCKEDY MIVNTEWGAL DIPELGYNKF
260 270 280 290 300
DKMIDDVSIN KGEHYFEKMI SGIYMGWLAR LAIRELIEKK VIFERYADAE
310 320 330 340 350
VFSGSPDDTD CDHSKKYTSR NTGIVEDTTP ELILVDEMLK SLGVNDSTLE
360 370 380 390 400
ERKMLKAITE AVVKRAAYLA AAATVCLYRK MVPYMKERTT AGVDGSVFEK
410 420 430 440
SVPFKRFYLE ALDLLQPVEK VTCQLSKDGS GLGAVIVAAA VACKQ
Length:445
Mass (Da):49,420
Last modified:November 1, 1996 - v1
Checksum:iEA230E13F00CCABF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK419612 mRNA. Translation: BAN38277.1.
X82198 mRNA. Translation: CAA57682.1.
DS571169 Genomic DNA. Translation: EAL50580.1.
RefSeqiXP_655965.1. XM_650873.1.

Genome annotation databases

EnsemblProtistsirna_EHI_098560-1; rna_EHI_098560-1; EHI_098560.
GeneIDi3410328.
KEGGiehi:EHI_098560.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK419612 mRNA. Translation: BAN38277.1.
X82198 mRNA. Translation: CAA57682.1.
DS571169 Genomic DNA. Translation: EAL50580.1.
RefSeqiXP_655965.1. XM_650873.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi5759.rna_EHI_098560-1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsirna_EHI_098560-1; rna_EHI_098560-1; EHI_098560.
GeneIDi3410328.
KEGGiehi:EHI_098560.

Organism-specific databases

EuPathDBiAmoebaDB:EHI_098560.

Phylogenomic databases

eggNOGiKOG1369. Eukaryota.
COG5026. LUCA.
KOiK00844.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PROSITEiPS51748. HEXOKINASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Molecular analysis of two hexokinase isoenzymes, pathogencity markers for the human parasite Entamoeba histolytica."
    Ortner S., Plaimauer B., Binder M., Scheiner O., Wiedermann G., Duchene M.
    Mol. Biochem. Parasitol. 73:189-198(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: SFL-3Imported.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 30459 / HM-1:IMSSImported and HM-1:IMSSImported.
  3. Lorenzi H., Amedeo P., Inman J., Schobel S., Caler E.
    Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: ATCC 30459 / HM-1:IMSSImported and HM-1:IMSSImported.
  4. "Short 5' UTR of Entamoeba genes."
    Hiranuka K., Kumagai M., Wakaguri H., Suzuki Y., Sugano S., Watanabe J., Makioka A.
    Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: HM-1:IMSSImported.

Entry informationi

Entry nameiQ27648_ENTHI
AccessioniPrimary (citable) accession number: Q27648
Secondary accession number(s): C4LXD6
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: May 11, 2016
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.