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Q27647

- Q27647_ENTHI

UniProt

Q27647 - Q27647_ENTHI

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Protein
Submitted name:

Hexokinase

Gene

HXK1

Organism
Entamoeba histolytica
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. hexokinase activity Source: UniProtKB-EC

GO - Biological processi

  1. glycolytic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseSAAS annotationImported, Transferase

Keywords - Biological processi

GlycolysisSAAS annotation

Keywords - Ligandi

ATP-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

SABIO-RKQ27647.

Names & Taxonomyi

Protein namesi
Submitted name:
HexokinaseImported (EC:2.7.1.1Imported)
Submitted name:
Hexokinase 1Imported
Gene namesi
Name:HXK1Imported
ORF Names:EHI_098290Imported
OrganismiEntamoeba histolyticaImported
Taxonomic identifieri5759 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaArchamoebaeEntamoebidaeEntamoeba
ProteomesiUP000001926: Partially assembled WGS sequence

Organism-specific databases

EuPathDBiAmoebaDB:EHI_098290.

Interactioni

Protein-protein interaction databases

STRINGi294381.C4LXB2.

Structurei

3D structure databases

ProteinModelPortaliQ27647.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotation

Phylogenomic databases

InParanoidiQ27647.
KOiK00844.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.

Sequencei

Sequence statusi: Complete.

Q27647 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MQEIIDQFAI DKEKMEIIVS KLLEEMENGL QDKPSTLQML PTYAPIPTGK
60 70 80 90 100
EVGTFMGIDV GGTNLRVLLL EIPEPGVRGE LKSVECIMPK TSTTVDQFFG
110 120 130 140 150
FIAQKIKEFV ENNNLKEKEI KAGLTFSFAV EQIAIDKGIQ QSWSKGWDVK
160 170 180 190 200
ESIGKDIVEI FHNQLAKINV NNIRIVAFIN DTVGTFANLA YDDASCGMGL
210 220 230 240 250
IFGTGTNGCY IEKTSNFAAS KLKSVYKEDY MIVNTEWGGL QFPELGLNRF
260 270 280 290 300
DDMINDVSVN KDQQRYEKMI SGIYMGWLAR LAIRELIEKK VIFERYADAE
310 320 330 340 350
VFSNSPDDTQ FNDKKKYSSR HTEIVEDTSP ELSRVDTILK SLGVNDSTLE
360 370 380 390 400
ERKILKAITE AVVKRAAYLS AAATVALYRK MVPYMKERTT AGIDGTVYEK
410 420 430 440
SVPFKRFYLE AIRLLQPKEN FTCQLSKDGS GLGAVIVAAA VACKH
Length:445
Mass (Da):49,830
Last modified:November 1, 1996 - v1
Checksum:iC5B888693A00826D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK418850 mRNA. Translation: BAN37591.1.
X82197 mRNA. Translation: CAA57681.1.
DS571169 Genomic DNA. Translation: EAL48234.1.
RefSeqiXP_653620.1. XM_648528.2.

Genome annotation databases

EnsemblProtistsirna_EHI_098290-1; rna_EHI_098290-1; EHI_098290.
GeneIDi3407925.
KEGGiehi:EHI_098290.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK418850 mRNA. Translation: BAN37591.1 .
X82197 mRNA. Translation: CAA57681.1 .
DS571169 Genomic DNA. Translation: EAL48234.1 .
RefSeqi XP_653620.1. XM_648528.2.

3D structure databases

ProteinModelPortali Q27647.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 294381.C4LXB2.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblProtistsi rna_EHI_098290-1 ; rna_EHI_098290-1 ; EHI_098290 .
GeneIDi 3407925.
KEGGi ehi:EHI_098290.

Organism-specific databases

EuPathDBi AmoebaDB:EHI_098290.

Phylogenomic databases

InParanoidi Q27647.
KOi K00844.

Enzyme and pathway databases

SABIO-RK Q27647.

Family and domain databases

InterProi IPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view ]
PANTHERi PTHR19443. PTHR19443. 1 hit.
Pfami PF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view ]
PRINTSi PR00475. HEXOKINASE.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Molecular analysis of two hexokinase isoenzymes, pathogencity markers for the human parasite Entamoeba histolytica."
    Ortner S., Plaimauer B., Binder M., Scheiner O., Wiedermann G., Duchene M.
    Mol. Biochem. Parasitol. 73:189-198(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: SFL-3Imported.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 30459 / HM-1:IMSSImported.
  3. Lorenzi H., Amedeo P., Inman J., Schobel S., Caler E.
    Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: ATCC 30459 / HM-1:IMSSImported.
  4. "Short 5' UTR of Entamoeba genes."
    Hiranuka K., Kumagai M., Wakaguri H., Suzuki Y., Sugano S., Watanabe J., Makioka A.
    Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: HM-1:IMSSImported.

Entry informationi

Entry nameiQ27647_ENTHI
AccessioniPrimary (citable) accession number: Q27647
Secondary accession number(s): C4LXB2
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: October 29, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3