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Protein

Phosphotransferase

Gene

HXK1

Organism
Entamoeba histolytica
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseUniRule annotationSAAS annotationImported, Transferase
Biological processGlycolysisUniRule annotationSAAS annotation
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

SABIO-RKiQ27647.

Names & Taxonomyi

Protein namesi
Recommended name:
PhosphotransferaseUniRule annotation (EC:2.7.1.-UniRule annotation)
Gene namesi
Name:HXK1Imported
ORF Names:EHI_098290Imported
OrganismiEntamoeba histolyticaImported
Taxonomic identifieri5759 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaArchamoebaeEntamoebidaeEntamoeba
Proteomesi
  • UP000001926 Componenti: Partially assembled WGS sequence

Organism-specific databases

EuPathDBiAmoebaDB:EHI_098290.

Subcellular locationi

GO - Cellular componenti

Interactioni

Protein-protein interaction databases

STRINGi5759.rna_EHI_098290-1.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 191Hexokinase_1InterPro annotationAdd BLAST190
Domaini198 – 439Hexokinase_2InterPro annotationAdd BLAST242

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG1369. Eukaryota.
COG5026. LUCA.
KOiK00844.
OMAiMIPTFVT.

Family and domain databases

InterProiView protein in InterPro
IPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiView protein in Pfam
PF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
PROSITEiView protein in PROSITE
PS51748. HEXOKINASE_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q27647-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQEIIDQFAI DKEKMEIIVS KLLEEMENGL QDKPSTLQML PTYAPIPTGK
60 70 80 90 100
EVGTFMGIDV GGTNLRVLLL EIPEPGVRGE LKSVECIMPK TSTTVDQFFG
110 120 130 140 150
FIAQKIKEFV ENNNLKEKEI KAGLTFSFAV EQIAIDKGIQ QSWSKGWDVK
160 170 180 190 200
ESIGKDIVEI FHNQLAKINV NNIRIVAFIN DTVGTFANLA YDDASCGMGL
210 220 230 240 250
IFGTGTNGCY IEKTSNFAAS KLKSVYKEDY MIVNTEWGGL QFPELGLNRF
260 270 280 290 300
DDMINDVSVN KDQQRYEKMI SGIYMGWLAR LAIRELIEKK VIFERYADAE
310 320 330 340 350
VFSNSPDDTQ FNDKKKYSSR HTEIVEDTSP ELSRVDTILK SLGVNDSTLE
360 370 380 390 400
ERKILKAITE AVVKRAAYLS AAATVALYRK MVPYMKERTT AGIDGTVYEK
410 420 430 440
SVPFKRFYLE AIRLLQPKEN FTCQLSKDGS GLGAVIVAAA VACKH
Length:445
Mass (Da):49,830
Last modified:November 1, 1996 - v1
Checksum:iC5B888693A00826D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK418850 mRNA. Translation: BAN37591.1.
X82197 mRNA. Translation: CAA57681.1.
DS571169 Genomic DNA. Translation: EAL48234.1.
RefSeqiXP_653620.1. XM_648528.2.

Genome annotation databases

EnsemblProtistsiGAT93385; GAT93385; CL6EHI_098290.
rna_EHI_098290-1; rna_EHI_098290-1; EHI_098290.
GeneIDi3407925.
KEGGiehi:EHI_098290.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK418850 mRNA. Translation: BAN37591.1.
X82197 mRNA. Translation: CAA57681.1.
DS571169 Genomic DNA. Translation: EAL48234.1.
RefSeqiXP_653620.1. XM_648528.2.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi5759.rna_EHI_098290-1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiGAT93385; GAT93385; CL6EHI_098290.
rna_EHI_098290-1; rna_EHI_098290-1; EHI_098290.
GeneIDi3407925.
KEGGiehi:EHI_098290.

Organism-specific databases

EuPathDBiAmoebaDB:EHI_098290.

Phylogenomic databases

eggNOGiKOG1369. Eukaryota.
COG5026. LUCA.
KOiK00844.
OMAiMIPTFVT.

Enzyme and pathway databases

SABIO-RKiQ27647.

Family and domain databases

InterProiView protein in InterPro
IPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiView protein in Pfam
PF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
PROSITEiView protein in PROSITE
PS51748. HEXOKINASE_2. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ27647_ENTHI
AccessioniPrimary (citable) accession number: Q27647
Secondary accession number(s): C4LXB2
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: June 7, 2017
This is version 90 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.