ID   K6PF_CALFI              Reviewed;         184 AA.
AC   Q27543;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   16-JUN-2009, entry version 43.
DE   RecName: Full=6-phosphofructokinase;
DE            Short=Phosphofructokinase;
DE            EC=2.7.1.11;
DE   AltName: Full=Phosphohexokinase;
DE   Flags: Fragment;
GN   Name=PFK;
OS   Calanus finmarchicus.
OC   Eukaryota; Metazoa; Arthropoda; Crustacea; Maxillopoda; Copepoda;
OC   Calanoida; Calanidae; Calanus.
OX   NCBI_TaxID=6837;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   MEDLINE=95400449; PubMed=7670600;
RA   Crawford D.L.;
RT   "Nuclear genes from the copepod Calanus finmarchicus.";
RL   Mol. Mar. Biol. Biotechnol. 4:241-247(1995).
CC   -!- CATALYTIC ACTIVITY: ATP + D-fructose 6-phosphate = ADP + D-
CC       fructose 1,6-bisphosphate.
CC   -!- PATHWAY: Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-
CC       phosphate and glycerone phosphate from D-glucose: step 3/4.
CC   -!- SIMILARITY: Belongs to the phosphofructokinase family. Two domains
CC       subfamily.
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DR   EMBL; U21244; AAA85287.1; -; mRNA.
DR   HSSP; P00512; 3PFK.
DR   BRENDA; 2.7.1.11; 297876.
DR   GO; GO:0005945; C:6-phosphofructokinase complex; IEA:InterPro.
DR   GO; GO:0003872; F:6-phosphofructokinase activity; IEA:EC.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
DR   InterPro; IPR000023; Phosphofructokinase.
DR   InterPro; IPR015912; Phosphofructokinase_CS.
DR   Pfam; PF00365; PFK; 1.
DR   PRINTS; PR00476; PHFRCTKINASE.
DR   ProDom; PD000707; Ppfruckinase; 1.
DR   PROSITE; PS00433; PHOSPHOFRUCTOKINASE; PARTIAL.
PE   2: Evidence at transcript level;
KW   ATP-binding; Glycolysis; Kinase; Nucleotide-binding; Transferase.
FT   CHAIN        <1   >184       6-phosphofructokinase.
FT                                /FTId=PRO_0000112028.
FT   NP_BIND      77     81       ATP (By similarity).
FT   NP_BIND      94    110       ATP (By similarity).
FT   ACT_SITE     50     50       Proton acceptor (By similarity).
FT   BINDING      85     85       Substrate (By similarity).
FT   BINDING     176    176       Substrate (By similarity).
FT   BINDING     182    182       Substrate (By similarity).
FT   NON_TER       1      1
FT   NON_TER     184    184
SQ   SEQUENCE   184 AA;  20208 MW;  E9B71F095A5DF2AD CRC64;
     GGDGSLTGAN RFKGEWSSLV KELLETGKIT KEVAEKHSHL NIVGMVGSID NDFCGTDMTI
     GTDSALHRIV EVADNIIPTA YSHQRAFVLE VMGRHCGYLA LVAGIVTEAD FVFAPEWPPE
     EDWPEKLCKK LELERQSGQR LNIIIVAEGA IDRQGNPITA EGVKKIIVDR LEMDTRTTVL
     GHIQ
//