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Q27543 (K6PF_CALFI) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 60. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
6-phosphofructokinase

Short name=Phosphofructokinase
EC=2.7.1.11
Alternative name(s):
Phosphohexokinase
Gene names
Name:PFK
OrganismCalanus finmarchicus (Calanus tonsus)
Taxonomic identifier6837 [NCBI]
Taxonomic lineageEukaryotaMetazoaEcdysozoaArthropodaCrustaceaMaxillopodaCopepodaCalanoidaCalanidaeCalanus

Protein attributes

Sequence length184 AA.
Sequence statusFragment.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

ATP + D-fructose 6-phosphate = ADP + D-fructose 1,6-bisphosphate.

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 3/4.

Sequence similarities

Belongs to the phosphofructokinase family. Two domains subfamily.

Ontologies

Keywords
   Biological processGlycolysis
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
Gene Ontology (GO)
   Biological_processfructose 6-phosphate metabolic process

Inferred from electronic annotation. Source: InterPro

glycolysis

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_component6-phosphofructokinase complex

Inferred from electronic annotation. Source: InterPro

   Molecular_function6-phosphofructokinase activity

Inferred from electronic annotation. Source: UniProtKB-EC

ATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain‹1 – ›184›1846-phosphofructokinase
PRO_0000112028

Regions

Nucleotide binding77 – 815ATP By similarity
Nucleotide binding94 – 11017ATP By similarity

Sites

Active site501Proton acceptor By similarity
Binding site851Substrate By similarity
Binding site1761Substrate By similarity
Binding site1821Substrate By similarity

Experimental info

Non-terminal residue11
Non-terminal residue1841

Sequences

Sequence LengthMass (Da)Tools
Q27543 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: E9B71F095A5DF2AD

FASTA18420,208
        10         20         30         40         50         60 
GGDGSLTGAN RFKGEWSSLV KELLETGKIT KEVAEKHSHL NIVGMVGSID NDFCGTDMTI 

        70         80         90        100        110        120 
GTDSALHRIV EVADNIIPTA YSHQRAFVLE VMGRHCGYLA LVAGIVTEAD FVFAPEWPPE 

       130        140        150        160        170        180 
EDWPEKLCKK LELERQSGQR LNIIIVAEGA IDRQGNPITA EGVKKIIVDR LEMDTRTTVL 


GHIQ 

« Hide

References

[1]"Nuclear genes from the copepod Calanus finmarchicus."
Crawford D.L.
Mol. Mar. Biol. Biotechnol. 4:241-247(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U21244 mRNA. Translation: AAA85287.1.

3D structure databases

ProteinModelPortalQ27543.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayUPA00109; UER00182.

Family and domain databases

InterProIPR022953. Phosphofructokinase.
IPR000023. Phosphofructokinase_dom.
[Graphical view]
PfamPF00365. PFK. 1 hit.
[Graphical view]
PRINTSPR00476. PHFRCTKINASE.
SUPFAMSSF53784. SSF53784. 1 hit.
ProtoNetSearch...

Entry information

Entry nameK6PF_CALFI
AccessionPrimary (citable) accession number: Q27543
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: April 16, 2014
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways