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Protein

Probable arginine kinase ZC434.8

Gene

ZC434.8

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine = ADP + N(omega)-phospho-L-arginine.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei189ATPPROSITE-ProRule annotation1
Binding sitei229SubstrateBy similarity1
Binding sitei233ATPPROSITE-ProRule annotation1
Binding sitei275SubstrateBy similarity1
Binding sitei317SubstrateBy similarity1
Binding sitei327ATPPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi125 – 129ATPPROSITE-ProRule annotation5
Nucleotide bindingi284 – 288ATPPROSITE-ProRule annotation5
Nucleotide bindingi312 – 317ATPPROSITE-ProRule annotation6

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Transferase
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-CEL-71288 Creatine metabolism

Names & Taxonomyi

Protein namesi
Recommended name:
Probable arginine kinase ZC434.8 (EC:2.7.3.3)
Short name:
AK
Gene namesi
ORF Names:ZC434.8
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome I

Organism-specific databases

WormBaseiZC434.8 ; CE06583 ; WBGene00013894

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002119891 – 360Probable arginine kinase ZC434.8Add BLAST360

Proteomic databases

EPDiQ27535
PaxDbiQ27535
PeptideAtlasiQ27535
PRIDEiQ27535

PTM databases

iPTMnetiQ27535

Expressioni

Gene expression databases

BgeeiWBGene00013894

Interactioni

Protein-protein interaction databases

BioGridi38324, 6 interactors
DIPiDIP-25633N
IntActiQ27535, 1 interactor
STRINGi6239.ZC434.8.2

Structurei

3D structure databases

ProteinModelPortaliQ27535
SMRiQ27535
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini10 – 92Phosphagen kinase N-terminalPROSITE-ProRule annotationAdd BLAST83
Domaini122 – 359Phosphagen kinase C-terminalPROSITE-ProRule annotationAdd BLAST238

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni65 – 69Substrate bindingBy similarity5

Sequence similaritiesi

Belongs to the ATP:guanido phosphotransferase family.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG3581 Eukaryota
COG3869 LUCA
GeneTreeiENSGT00550000074561
HOGENOMiHOG000232165
InParanoidiQ27535
KOiK00933
OMAiTNYKMME
OrthoDBiEOG091G0HZ0
PhylomeDBiQ27535

Family and domain databases

Gene3Di1.10.135.10, 1 hit
InterProiView protein in InterPro
IPR000749 ATP-guanido_PTrfase
IPR022415 ATP-guanido_PTrfase_AS
IPR022414 ATP-guanido_PTrfase_cat
IPR022413 ATP-guanido_PTrfase_N
IPR036802 ATP-guanido_PTrfase_N_sf
IPR014746 Gln_synth/guanido_kin_cat_dom
PANTHERiPTHR11547 PTHR11547, 1 hit
PfamiView protein in Pfam
PF00217 ATP-gua_Ptrans, 1 hit
PF02807 ATP-gua_PtransN, 1 hit
SUPFAMiSSF48034 SSF48034, 1 hit
SSF55931 SSF55931, 1 hit
PROSITEiView protein in PROSITE
PS00112 PHOSPHAGEN_KINASE, 1 hit
PS51510 PHOSPHAGEN_KINASE_C, 1 hit
PS51509 PHOSPHAGEN_KINASE_N, 1 hit

Sequencei

Sequence statusi: Complete.

Q27535-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTATPEVQKS IEEVYTKLQG ASDCSSLLKK HLTKDVVAKN KSKKTRLGAT
60 70 80 90 100
LLDVIQSGGE NLDSGVGIYA PDAESYTLFA DLFNPVIEEY HNGFKATDTQ
110 120 130 140 150
PAMDLGEKNV GELADLDPEG KFIVSTRIRC GRSLQGYPFN PCLSETNYKM
160 170 180 190 200
METRMKEIFN SITDPELKGT YYPLTGMDEE TKKKLIADHF LFKEGDRFLK
210 220 230 240 250
AANANRYWPN GRGIFHNEKK TFLVWVNEED HLRIISMQNG GNVGEVLARL
260 270 280 290 300
IKGLNLVAAK APFARHPRLG WLTFCPTNLG TTVRASVHIK LPKISAKDDF
310 320 330 340 350
KKICSDMKLQ IRGIHGEHSE SKEGIYDISN KQRLGLTEYQ AVRQMYDGLK
360
KLIELEKAAA
Length:360
Mass (Da):40,382
Last modified:November 1, 1996 - v1
Checksum:i176760B381EF26D7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z75714 Genomic DNA Translation: CAB00062.1
PIRiT27569
RefSeqiNP_492714.1, NM_060313.7
UniGeneiCel.7229

Genome annotation databases

EnsemblMetazoaiZC434.8.1; ZC434.8.1; WBGene00013894
ZC434.8.2; ZC434.8.2; WBGene00013894
GeneIDi172907
KEGGicel:CELE_ZC434.8
UCSCiZC434.8.1 c. elegans

Similar proteinsi

Entry informationi

Entry nameiKARG2_CAEEL
AccessioniPrimary (citable) accession number: Q27535
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: November 1, 1996
Last modified: May 23, 2018
This is version 112 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families

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