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Protein

Serine/threonine-protein phosphatase

Gene

CELE_T25B9.2

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

HydrolaseUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein phosphataseUniRule annotation (EC:3.1.3.16UniRule annotation)
Gene namesi
ORF Names:CELE_T25B9.2Imported, T25B9.2Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome IV

Organism-specific databases

WormBaseiT25B9.2; CE43296; WBGene00012008.

PTM / Processingi

Proteomic databases

PaxDbiQ27528.

Interactioni

Protein-protein interaction databases

STRINGi6239.T25B9.2.

Structurei

3D structure databases

ProteinModelPortaliQ27528.
SMRiQ27528. Positions 8-326.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini149 – 1546SER_THR_PHOSPHATASEInterPro annotation

Sequence similaritiesi

Belongs to the PPP phosphatase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0374. Eukaryota.
COG0639. LUCA.
GeneTreeiENSGT00530000062911.
HOGENOMiHOG000172697.
InParanoidiQ27528.
OMAiTARYDQK.
OrthoDBiEOG7R835G.
PhylomeDBiQ27528.

Family and domain databases

Gene3Di3.60.21.10. 2 hits.
InterProiIPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
IPR006186. Ser/Thr-sp_prot-phosphatase.
[Graphical view]
PfamiPF00149. Metallophos. 1 hit.
[Graphical view]
PRINTSiPR00114. STPHPHTASE.
SMARTiSM00156. PP2Ac. 1 hit.
[Graphical view]
SUPFAMiSSF56300. SSF56300. 2 hits.
PROSITEiPS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q27528-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDLFCAAELA ELCHRARELI WSEPIFLKLE APICVMGDIH GQFDDLLAML
60 70 80 90 100
DMNGWPLSSQ EFEALKDITV RSRETGKRPQ SEPHSTQPES SNDVKPPVAA
110 120 130 140 150
PKSVNKEVTT GYKRYLFLGD YVDRGPFSME VVILLTALKL AYPDRIYLLR
160 170 180 190 200
GNHESRSVNT SYGFYREVNY RYDAQLYECF QNMFNVFPFC AVINNTIMCM
210 220 230 240 250
HGGISEHLTS FNQFSVFKRP LEIPDVGVLT DLTWADPDPT EKGYKPSARG
260 270 280 290 300
ASFVFGPPAL RAFLKKLDLQ MVIRGHQVVE DGYEFFDGRR LVTIFSAPNY
310 320 330 340
CGQNDNTAAV FSIDKKLKIS INVFRPESRD KKRGFEKERK AKK
Length:343
Mass (Da):39,142
Last modified:December 16, 2008 - v2
Checksum:i67A2666DF0A337D2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA. Translation: CAA94374.2.
RefSeqiNP_501992.2. NM_069591.2.
UniGeneiCel.29195.

Genome annotation databases

EnsemblMetazoaiT25B9.2; T25B9.2; WBGene00012008.
GeneIDi188880.
KEGGicel:CELE_T25B9.2.
UCSCiT25B9.2. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA. Translation: CAA94374.2.
RefSeqiNP_501992.2. NM_069591.2.
UniGeneiCel.29195.

3D structure databases

ProteinModelPortaliQ27528.
SMRiQ27528. Positions 8-326.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.T25B9.2.

Proteomic databases

PaxDbiQ27528.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiT25B9.2; T25B9.2; WBGene00012008.
GeneIDi188880.
KEGGicel:CELE_T25B9.2.
UCSCiT25B9.2. c. elegans.

Organism-specific databases

CTDi188880.
WormBaseiT25B9.2; CE43296; WBGene00012008.

Phylogenomic databases

eggNOGiKOG0374. Eukaryota.
COG0639. LUCA.
GeneTreeiENSGT00530000062911.
HOGENOMiHOG000172697.
InParanoidiQ27528.
OMAiTARYDQK.
OrthoDBiEOG7R835G.
PhylomeDBiQ27528.

Family and domain databases

Gene3Di3.60.21.10. 2 hits.
InterProiIPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
IPR006186. Ser/Thr-sp_prot-phosphatase.
[Graphical view]
PfamiPF00149. Metallophos. 1 hit.
[Graphical view]
PRINTSiPR00114. STPHPHTASE.
SMARTiSM00156. PP2Ac. 1 hit.
[Graphical view]
SUPFAMiSSF56300. SSF56300. 2 hits.
PROSITEiPS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    Caenorhabditis elegans Sequencing Consortium
    Sulson J.E., Waterston R.
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2Imported.

Entry informationi

Entry nameiQ27528_CAEEL
AccessioniPrimary (citable) accession number: Q27528
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: December 16, 2008
Last modified: March 16, 2016
This is version 109 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.