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Protein

Beta-galactosidase

Gene

bgal-1

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseUniRule annotationSAAS annotation, Hydrolase

Enzyme and pathway databases

ReactomeiR-CEL-1660662. Glycosphingolipid metabolism.
R-CEL-2022857. Keratan sulfate degradation.
R-CEL-2024096. HS-GAG degradation.

Protein family/group databases

CAZyiGH35. Glycoside Hydrolase Family 35.

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-galactosidaseUniRule annotation (EC:3.2.1.23UniRule annotation)
Gene namesi
Name:bgal-1Imported
ORF Names:CELE_T19B10.3Imported, T19B10.3Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome V

Organism-specific databases

WormBaseiT19B10.3; CE37992; WBGene00011832; bgal-1.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2020Sequence analysisAdd
BLAST
Chaini21 – 653633Beta-galactosidaseSequence analysisPRO_5004203548Add
BLAST

Proteomic databases

EPDiQ27526.
PaxDbiQ27526.
PRIDEiQ27526.

Interactioni

Protein-protein interaction databases

STRINGi6239.T19B10.3.

Structurei

3D structure databases

ProteinModelPortaliQ27526.
SMRiQ27526. Positions 46-629.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini50 – 369320Glyco_hydro_35InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the glycosyl hydrolase 35 family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG0496. Eukaryota.
COG1874. LUCA.
GeneTreeiENSGT00390000006586.
HOGENOMiHOG000221607.
InParanoidiQ27526.
KOiK12309.
OMAiDFGTDTN.
OrthoDBiEOG7GXPCD.
PhylomeDBiQ27526.

Family and domain databases

Gene3Di2.60.120.260. 1 hit.
3.20.20.80. 1 hit.
InterProiIPR026283. B-gal_1-like.
IPR008979. Galactose-bd-like.
IPR031330. Gly_Hdrlase_35_cat.
IPR019801. Glyco_hydro_35_CS.
IPR013781. Glyco_hydro_catalytic_dom.
IPR001944. Glycoside_Hdrlase_35.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR23421. PTHR23421. 1 hit.
PfamiPF01301. Glyco_hydro_35. 1 hit.
[Graphical view]
PIRSFiPIRSF006336. B-gal. 1 hit.
PRINTSiPR00742. GLHYDRLASE35.
SUPFAMiSSF49785. SSF49785. 1 hit.
SSF51445. SSF51445. 1 hit.
PROSITEiPS01182. GLYCOSYL_HYDROL_F35. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q27526-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MELWKSCIFL FLNFCIQSEG IVRTSYGNWN IPKIGDRNIP SFLIDESKNQ
60 70 80 90 100
FLLDGLPFRY ISGSIHYFRI PRDRWDERLG KVRALGFNAI QYYIPWNMHE
110 120 130 140 150
LEEGNHDFSG LLDFAEFSMM AFHKYGLWTI LRVGPYICGE LENGGLPWWL
160 170 180 190 200
LNKNVTKQRS SDRVFTREVE NWFEILLPRV KPLLRKNGGP VLMLQIENEY
210 220 230 240 250
GSYDACDQQY LRFLRDLTRS LVGDDVLLFT TDGSAESLLK CGTVEGVFPT
260 270 280 290 300
VDFGPTDDAK EIENNFKLQR KFAPNGPLVN SEYYPGWLVL WGQKKQNLPS
310 320 330 340 350
PQTIINGSQT MYSLGASFNY YMIHGGTNFG FWNGAETEAP CITSYDYDAP
360 370 380 390 400
ISESGDVTTK YLEIRKWIKG LTDWPTPPLD VPGNSPKGRF GKIKMRLVHS
410 420 430 440 450
VEKLKTLTSL GDPGDCVETD KPISFETLKH PLGLVAYQAK INSCGNLTIP
460 470 480 490 500
SFGDFVHVYL NGKYIDTLTR RYYNLTRNSV IIEGCLENEE NRLFMLVENQ
510 520 530 540 550
GRKTFETIND RKGILSDVFM NGQAIQFWTQ CGIKLPLQED FYFRKAMRNN
560 570 580 590 600
YRKNVKSNQK QGVFIGILSV DAPTDTWLDT TGWGKGIAIV NGRNFGRYWP
610 620 630 640 650
TKGPQMTLYI PAEFLKIGEN SVMMVELEGA EEACTSTSSC IADFIDHPVF

DFQ
Length:653
Mass (Da):74,631
Last modified:March 1, 2005 - v2
Checksum:i24F5C7D712A905C4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284605 Genomic DNA. Translation: CAA98542.2.
PIRiT24978.
RefSeqiNP_505849.2. NM_073448.7.
UniGeneiCel.37613.

Genome annotation databases

EnsemblMetazoaiT19B10.3; T19B10.3; WBGene00011832.
GeneIDi188583.
KEGGicel:CELE_T19B10.3.
UCSCiT19B10.3. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284605 Genomic DNA. Translation: CAA98542.2.
PIRiT24978.
RefSeqiNP_505849.2. NM_073448.7.
UniGeneiCel.37613.

3D structure databases

ProteinModelPortaliQ27526.
SMRiQ27526. Positions 46-629.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.T19B10.3.

Protein family/group databases

CAZyiGH35. Glycoside Hydrolase Family 35.

Proteomic databases

EPDiQ27526.
PaxDbiQ27526.
PRIDEiQ27526.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiT19B10.3; T19B10.3; WBGene00011832.
GeneIDi188583.
KEGGicel:CELE_T19B10.3.
UCSCiT19B10.3. c. elegans.

Organism-specific databases

CTDi188583.
WormBaseiT19B10.3; CE37992; WBGene00011832; bgal-1.

Phylogenomic databases

eggNOGiKOG0496. Eukaryota.
COG1874. LUCA.
GeneTreeiENSGT00390000006586.
HOGENOMiHOG000221607.
InParanoidiQ27526.
KOiK12309.
OMAiDFGTDTN.
OrthoDBiEOG7GXPCD.
PhylomeDBiQ27526.

Enzyme and pathway databases

ReactomeiR-CEL-1660662. Glycosphingolipid metabolism.
R-CEL-2022857. Keratan sulfate degradation.
R-CEL-2024096. HS-GAG degradation.

Family and domain databases

Gene3Di2.60.120.260. 1 hit.
3.20.20.80. 1 hit.
InterProiIPR026283. B-gal_1-like.
IPR008979. Galactose-bd-like.
IPR031330. Gly_Hdrlase_35_cat.
IPR019801. Glyco_hydro_35_CS.
IPR013781. Glyco_hydro_catalytic_dom.
IPR001944. Glycoside_Hdrlase_35.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR23421. PTHR23421. 1 hit.
PfamiPF01301. Glyco_hydro_35. 1 hit.
[Graphical view]
PIRSFiPIRSF006336. B-gal. 1 hit.
PRINTSiPR00742. GLHYDRLASE35.
SUPFAMiSSF49785. SSF49785. 1 hit.
SSF51445. SSF51445. 1 hit.
PROSITEiPS01182. GLYCOSYL_HYDROL_F35. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    Caenorhabditis elegans Sequencing Consortium
    Sulson J.E., Waterston R.
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2Imported.

Entry informationi

Entry nameiQ27526_CAEEL
AccessioniPrimary (citable) accession number: Q27526
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: March 1, 2005
Last modified: June 8, 2016
This is version 125 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.